| Full name: LDL receptor related protein 10 | Alias Symbol: DKFZP564C1940|MGC8675|LRP9|MST087|MSTP087 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 26020 | HGNC ID: HGNC:14553 | Ensembl Gene: ENSG00000197324 | OMIM ID: 609921 |
| Drug and gene relationship at DGIdb | |||
Expression of LRP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRP10 | 26020 | 201412_at | -0.9072 | 0.0402 | |
| GSE20347 | LRP10 | 26020 | 201412_at | -1.7316 | 0.0000 | |
| GSE23400 | LRP10 | 26020 | 201412_at | -1.2068 | 0.0000 | |
| GSE26886 | LRP10 | 26020 | 201412_at | -1.4586 | 0.0000 | |
| GSE29001 | LRP10 | 26020 | 201412_at | -1.5089 | 0.0000 | |
| GSE38129 | LRP10 | 26020 | 201412_at | -1.4043 | 0.0000 | |
| GSE45670 | LRP10 | 26020 | 201412_at | -0.4626 | 0.0082 | |
| GSE53622 | LRP10 | 26020 | 68647 | -1.3484 | 0.0000 | |
| GSE53624 | LRP10 | 26020 | 68647 | -1.3455 | 0.0000 | |
| GSE63941 | LRP10 | 26020 | 201412_at | -1.4131 | 0.0207 | |
| GSE77861 | LRP10 | 26020 | 201412_at | -1.1123 | 0.0065 | |
| GSE97050 | LRP10 | 26020 | A_24_P99216 | -0.0545 | 0.8476 | |
| SRP007169 | LRP10 | 26020 | RNAseq | -2.6504 | 0.0000 | |
| SRP008496 | LRP10 | 26020 | RNAseq | -2.6101 | 0.0000 | |
| SRP064894 | LRP10 | 26020 | RNAseq | -1.1009 | 0.0000 | |
| SRP133303 | LRP10 | 26020 | RNAseq | -0.9364 | 0.0000 | |
| SRP159526 | LRP10 | 26020 | RNAseq | -1.5308 | 0.0005 | |
| SRP193095 | LRP10 | 26020 | RNAseq | -1.1990 | 0.0000 | |
| SRP219564 | LRP10 | 26020 | RNAseq | -1.3100 | 0.0000 | |
| TCGA | LRP10 | 26020 | RNAseq | -0.2510 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by LRP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRP10 | 26020 | 9 | 2 | 19 | |
| GSE20123 | LRP10 | 26020 | 9 | 2 | 19 | |
| GSE43470 | LRP10 | 26020 | 7 | 2 | 34 | |
| GSE46452 | LRP10 | 26020 | 17 | 2 | 40 | |
| GSE47630 | LRP10 | 26020 | 11 | 10 | 19 | |
| GSE54993 | LRP10 | 26020 | 3 | 11 | 56 | |
| GSE54994 | LRP10 | 26020 | 18 | 5 | 30 | |
| GSE60625 | LRP10 | 26020 | 0 | 2 | 9 | |
| GSE74703 | LRP10 | 26020 | 6 | 2 | 28 | |
| GSE74704 | LRP10 | 26020 | 4 | 1 | 15 | |
| TCGA | LRP10 | 26020 | 26 | 16 | 54 |
Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.
Somatic mutations of LRP10:
Generating mutation plots.
Highly correlated genes for LRP10:
Showing top 20/1765 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRP10 | VSIG10L | 0.862561 | 6 | 0 | 6 |
| LRP10 | FCHO2 | 0.860632 | 7 | 0 | 7 |
| LRP10 | BNIPL | 0.839366 | 6 | 0 | 6 |
| LRP10 | GDPD3 | 0.838472 | 10 | 0 | 10 |
| LRP10 | CYSRT1 | 0.834293 | 6 | 0 | 6 |
| LRP10 | KALRN | 0.83011 | 7 | 0 | 7 |
| LRP10 | CRISP3 | 0.825678 | 10 | 0 | 10 |
| LRP10 | NLRX1 | 0.825506 | 10 | 0 | 10 |
| LRP10 | SFTA2 | 0.823081 | 4 | 0 | 4 |
| LRP10 | MXD1 | 0.822133 | 10 | 0 | 10 |
| LRP10 | EPS8L1 | 0.819783 | 10 | 0 | 10 |
| LRP10 | SLC16A6 | 0.81635 | 11 | 0 | 11 |
| LRP10 | SPINK5 | 0.816149 | 10 | 0 | 10 |
| LRP10 | SPAG17 | 0.816117 | 4 | 0 | 4 |
| LRP10 | GYS2 | 0.815279 | 10 | 0 | 10 |
| LRP10 | PDCD6IP | 0.812993 | 11 | 0 | 11 |
| LRP10 | SMIM5 | 0.812782 | 6 | 0 | 6 |
| LRP10 | TMPRSS11E | 0.812609 | 10 | 0 | 10 |
| LRP10 | RMND5B | 0.81177 | 11 | 0 | 11 |
| LRP10 | SCNN1B | 0.811362 | 11 | 0 | 10 |
For details and further investigation, click here
