MGLL

 

Full name: monoglyceride lipase Alias Symbol: HU-K5|MGL
Type: protein-coding gene Cytoband: 3q21.3
Entrez ID: 11343 HGNC ID: HGNC:17038 Ensembl Gene: ENSG00000074416 OMIM ID: 609699
Drug and gene relationship at DGIdb

 

Expression of MGLL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MGLL 11343 211026_s_at -2.3969 0.0171
GSE20347 MGLL 11343 211026_s_at -3.2338 0.0000
GSE23400 MGLL 11343 211026_s_at -1.9209 0.0000
GSE26886 MGLL 11343 225102_at -3.2597 0.0000
GSE29001 MGLL 11343 211026_s_at -2.8396 0.0000
GSE38129 MGLL 11343 211026_s_at -2.8463 0.0000
GSE45670 MGLL 11343 211026_s_at -1.6439 0.0011
GSE53622 MGLL 11343 19378 -2.9364 0.0000
GSE53624 MGLL 11343 19378 -3.0425 0.0000
GSE63941 MGLL 11343 225102_at -2.9785 0.0035
GSE77861 MGLL 11343 211026_s_at -1.8465 0.0132
GSE97050 MGLL 11343 A_24_P226008 -1.6078 0.0828
SRP007169 MGLL 11343 RNAseq -3.4574 0.0000
SRP008496 MGLL 11343 RNAseq -3.5013 0.0000
SRP064894 MGLL 11343 RNAseq -2.3902 0.0000
SRP133303 MGLL 11343 RNAseq -2.7011 0.0000
SRP159526 MGLL 11343 RNAseq -2.7797 0.0000
SRP193095 MGLL 11343 RNAseq -2.3373 0.0000
SRP219564 MGLL 11343 RNAseq -2.0489 0.0001
TCGA MGLL 11343 RNAseq -0.4058 0.0013

Upregulated datasets: 0; Downregulated datasets: 18.  


 

Survival by MGLL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MGLL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MGLL 11343 17 0 13
GSE20123 MGLL 11343 17 0 13
GSE43470 MGLL 11343 19 0 24
GSE46452 MGLL 11343 14 5 40
GSE47630 MGLL 11343 17 4 19
GSE54993 MGLL 11343 2 7 61
GSE54994 MGLL 11343 31 3 19
GSE60625 MGLL 11343 0 6 5
GSE74703 MGLL 11343 17 0 19
GSE74704 MGLL 11343 13 0 7
TCGA MGLL 11343 56 6 34

Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.  


 

Somatic mutations of MGLL:

 

Generating mutation plots.

 

Highly correlated genes for MGLL:

 

Showing top 20/1682 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MGLLSH3BGRL20.884257707
MGLLSPINK70.882243606
MGLLCYSRT10.881431606
MGLLVSIG10L0.877472606
MGLLKRT780.876032707
MGLLSNORA680.871269404
MGLLSCNN1B0.86613810010
MGLLGDPD30.85779810010
MGLLSASH10.85752312012
MGLLFAM214A0.85747606
MGLLPPP1R3C0.85664412012
MGLLCRISP30.85630511011
MGLLMALL0.84717410010
MGLLTMPRSS11E0.84393110010
MGLLPLEKHM10.84221611011
MGLLCLIC30.841403909
MGLLEHD30.83819512012
MGLLGYS20.83726110010
MGLLCLCA40.83551610010
MGLLCAST0.83510711011

For details and further investigation, click here