| Full name: ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | Alias Symbol: ST3GALII|ST3GalA.2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 6483 | HGNC ID: HGNC:10863 | Ensembl Gene: ENSG00000157350 | OMIM ID: 607188 |
| Drug and gene relationship at DGIdb | |||
Expression of ST3GAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST3GAL2 | 6483 | 217650_x_at | 0.1278 | 0.6702 | |
| GSE20347 | ST3GAL2 | 6483 | 217650_x_at | 0.3606 | 0.0009 | |
| GSE23400 | ST3GAL2 | 6483 | 217650_x_at | 0.0326 | 0.4437 | |
| GSE26886 | ST3GAL2 | 6483 | 217650_x_at | 0.6989 | 0.0000 | |
| GSE29001 | ST3GAL2 | 6483 | 217650_x_at | 0.3441 | 0.0059 | |
| GSE38129 | ST3GAL2 | 6483 | 217650_x_at | 0.1584 | 0.0834 | |
| GSE45670 | ST3GAL2 | 6483 | 217650_x_at | 0.1217 | 0.3554 | |
| GSE53622 | ST3GAL2 | 6483 | 104975 | 0.7526 | 0.0000 | |
| GSE53624 | ST3GAL2 | 6483 | 104975 | 0.7753 | 0.0000 | |
| GSE63941 | ST3GAL2 | 6483 | 217650_x_at | -1.1674 | 0.0006 | |
| GSE77861 | ST3GAL2 | 6483 | 229336_at | 0.0222 | 0.8276 | |
| GSE97050 | ST3GAL2 | 6483 | A_24_P48177 | 0.1763 | 0.3833 | |
| SRP007169 | ST3GAL2 | 6483 | RNAseq | 1.8428 | 0.0001 | |
| SRP008496 | ST3GAL2 | 6483 | RNAseq | 2.0197 | 0.0000 | |
| SRP064894 | ST3GAL2 | 6483 | RNAseq | 0.8372 | 0.0000 | |
| SRP133303 | ST3GAL2 | 6483 | RNAseq | 0.4035 | 0.0024 | |
| SRP159526 | ST3GAL2 | 6483 | RNAseq | 0.9601 | 0.0066 | |
| SRP193095 | ST3GAL2 | 6483 | RNAseq | 0.8164 | 0.0000 | |
| SRP219564 | ST3GAL2 | 6483 | RNAseq | 0.4378 | 0.4059 | |
| TCGA | ST3GAL2 | 6483 | RNAseq | 0.1307 | 0.1721 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ST3GAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST3GAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST3GAL2 | 6483 | 6 | 1 | 23 | |
| GSE20123 | ST3GAL2 | 6483 | 6 | 1 | 23 | |
| GSE43470 | ST3GAL2 | 6483 | 2 | 8 | 33 | |
| GSE46452 | ST3GAL2 | 6483 | 38 | 1 | 20 | |
| GSE47630 | ST3GAL2 | 6483 | 11 | 8 | 21 | |
| GSE54993 | ST3GAL2 | 6483 | 2 | 4 | 64 | |
| GSE54994 | ST3GAL2 | 6483 | 8 | 11 | 34 | |
| GSE60625 | ST3GAL2 | 6483 | 4 | 0 | 7 | |
| GSE74703 | ST3GAL2 | 6483 | 2 | 5 | 29 | |
| GSE74704 | ST3GAL2 | 6483 | 3 | 0 | 17 | |
| TCGA | ST3GAL2 | 6483 | 27 | 12 | 57 |
Total number of gains: 109; Total number of losses: 51; Total Number of normals: 328.
Somatic mutations of ST3GAL2:
Generating mutation plots.
Highly correlated genes for ST3GAL2:
Showing top 20/1039 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST3GAL2 | TK2 | 0.82843 | 3 | 0 | 3 |
| ST3GAL2 | C11orf96 | 0.826184 | 3 | 0 | 3 |
| ST3GAL2 | MRC2 | 0.811998 | 3 | 0 | 3 |
| ST3GAL2 | CRLF1 | 0.7941 | 3 | 0 | 3 |
| ST3GAL2 | STK17A | 0.788641 | 3 | 0 | 3 |
| ST3GAL2 | NPHP3 | 0.788561 | 3 | 0 | 3 |
| ST3GAL2 | GNG2 | 0.775523 | 3 | 0 | 3 |
| ST3GAL2 | SLC16A4 | 0.764786 | 3 | 0 | 3 |
| ST3GAL2 | SLC39A3 | 0.75609 | 3 | 0 | 3 |
| ST3GAL2 | PTOV1 | 0.755466 | 3 | 0 | 3 |
| ST3GAL2 | PDE7B | 0.735932 | 3 | 0 | 3 |
| ST3GAL2 | CYP27A1 | 0.733727 | 3 | 0 | 3 |
| ST3GAL2 | TMEM263 | 0.727885 | 5 | 0 | 5 |
| ST3GAL2 | PRKACA | 0.727701 | 3 | 0 | 3 |
| ST3GAL2 | ZNF579 | 0.725229 | 3 | 0 | 3 |
| ST3GAL2 | FAM20C | 0.724703 | 5 | 0 | 5 |
| ST3GAL2 | SLC39A13 | 0.721281 | 6 | 0 | 5 |
| ST3GAL2 | PKIG | 0.719043 | 3 | 0 | 3 |
| ST3GAL2 | FADS1 | 0.717708 | 3 | 0 | 3 |
| ST3GAL2 | LRRC8C | 0.717258 | 3 | 0 | 3 |
For details and further investigation, click here
