| Full name: cytochrome P450 family 27 subfamily C member 1 | Alias Symbol: FLJ16008 | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 339761 | HGNC ID: HGNC:33480 | Ensembl Gene: ENSG00000186684 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CYP27C1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP27C1 | 339761 | 1568868_at | 1.9591 | 0.1165 | |
| GSE26886 | CYP27C1 | 339761 | 1568868_at | 1.0864 | 0.0093 | |
| GSE45670 | CYP27C1 | 339761 | 1568868_at | 1.8542 | 0.0002 | |
| GSE53622 | CYP27C1 | 339761 | 4566 | 1.3063 | 0.0000 | |
| GSE53624 | CYP27C1 | 339761 | 4566 | 1.1839 | 0.0000 | |
| GSE63941 | CYP27C1 | 339761 | 1568868_at | -0.1324 | 0.8641 | |
| GSE77861 | CYP27C1 | 339761 | 1568868_at | 0.1404 | 0.2624 | |
| GSE97050 | CYP27C1 | 339761 | A_33_P3264662 | 0.3822 | 0.2066 | |
| SRP007169 | CYP27C1 | 339761 | RNAseq | 1.1180 | 0.0895 | |
| SRP064894 | CYP27C1 | 339761 | RNAseq | 2.0766 | 0.0000 | |
| SRP133303 | CYP27C1 | 339761 | RNAseq | 1.2181 | 0.0001 | |
| SRP193095 | CYP27C1 | 339761 | RNAseq | 0.7919 | 0.0000 | |
| SRP219564 | CYP27C1 | 339761 | RNAseq | 1.1012 | 0.0615 | |
| TCGA | CYP27C1 | 339761 | RNAseq | 1.3304 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by CYP27C1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP27C1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP27C1 | 339761 | 4 | 3 | 23 | |
| GSE20123 | CYP27C1 | 339761 | 4 | 3 | 23 | |
| GSE43470 | CYP27C1 | 339761 | 2 | 1 | 40 | |
| GSE46452 | CYP27C1 | 339761 | 1 | 3 | 55 | |
| GSE47630 | CYP27C1 | 339761 | 6 | 0 | 34 | |
| GSE54993 | CYP27C1 | 339761 | 0 | 6 | 64 | |
| GSE54994 | CYP27C1 | 339761 | 11 | 0 | 42 | |
| GSE60625 | CYP27C1 | 339761 | 0 | 3 | 8 | |
| GSE74703 | CYP27C1 | 339761 | 2 | 1 | 33 | |
| GSE74704 | CYP27C1 | 339761 | 2 | 1 | 17 | |
| TCGA | CYP27C1 | 339761 | 22 | 8 | 66 |
Total number of gains: 54; Total number of losses: 29; Total Number of normals: 405.
Somatic mutations of CYP27C1:
Generating mutation plots.
Highly correlated genes for CYP27C1:
Showing top 20/1093 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP27C1 | PPP6R3 | 0.808239 | 3 | 0 | 3 |
| CYP27C1 | MSRB1 | 0.796399 | 3 | 0 | 3 |
| CYP27C1 | ABCB6 | 0.796323 | 3 | 0 | 3 |
| CYP27C1 | CCT6A | 0.795074 | 3 | 0 | 3 |
| CYP27C1 | GINS4 | 0.78891 | 3 | 0 | 3 |
| CYP27C1 | XAB2 | 0.787952 | 3 | 0 | 3 |
| CYP27C1 | STK17A | 0.786532 | 5 | 0 | 5 |
| CYP27C1 | PXMP2 | 0.78602 | 3 | 0 | 3 |
| CYP27C1 | ITPK1 | 0.779107 | 3 | 0 | 3 |
| CYP27C1 | SLC39A1 | 0.777636 | 4 | 0 | 4 |
| CYP27C1 | IRF9 | 0.775856 | 3 | 0 | 3 |
| CYP27C1 | POFUT1 | 0.769104 | 3 | 0 | 3 |
| CYP27C1 | ZMIZ2 | 0.767529 | 3 | 0 | 3 |
| CYP27C1 | MGAT2 | 0.765397 | 4 | 0 | 4 |
| CYP27C1 | C1orf226 | 0.753814 | 3 | 0 | 3 |
| CYP27C1 | RUNX3 | 0.751979 | 3 | 0 | 3 |
| CYP27C1 | CERCAM | 0.751133 | 4 | 0 | 4 |
| CYP27C1 | ZNF114 | 0.748856 | 4 | 0 | 4 |
| CYP27C1 | PLAGL2 | 0.748056 | 3 | 0 | 3 |
| CYP27C1 | CENPBD1 | 0.741673 | 3 | 0 | 3 |
For details and further investigation, click here
