| Full name: TNF alpha induced protein 8 | Alias Symbol: GG2-1|MDC-3.13|SCC-S2 | ||
| Type: protein-coding gene | Cytoband: 5q23.1 | ||
| Entrez ID: 25816 | HGNC ID: HGNC:17260 | Ensembl Gene: ENSG00000145779 | OMIM ID: 612111 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFAIP8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFAIP8 | 25816 | 210260_s_at | -0.0561 | 0.9601 | |
| GSE20347 | TNFAIP8 | 25816 | 210260_s_at | -0.1104 | 0.6075 | |
| GSE23400 | TNFAIP8 | 25816 | 210260_s_at | 0.2163 | 0.0307 | |
| GSE26886 | TNFAIP8 | 25816 | 210260_s_at | -0.5257 | 0.0249 | |
| GSE29001 | TNFAIP8 | 25816 | 208296_x_at | 0.5071 | 0.0618 | |
| GSE38129 | TNFAIP8 | 25816 | 210260_s_at | -0.1571 | 0.4579 | |
| GSE45670 | TNFAIP8 | 25816 | 210260_s_at | 0.1518 | 0.4597 | |
| GSE53622 | TNFAIP8 | 25816 | 43144 | -0.1241 | 0.1311 | |
| GSE53624 | TNFAIP8 | 25816 | 43144 | 0.0786 | 0.2864 | |
| GSE63941 | TNFAIP8 | 25816 | 210260_s_at | -0.3587 | 0.5488 | |
| GSE77861 | TNFAIP8 | 25816 | 210260_s_at | -0.2059 | 0.6824 | |
| GSE97050 | TNFAIP8 | 25816 | A_32_P219520 | 0.3724 | 0.2724 | |
| SRP007169 | TNFAIP8 | 25816 | RNAseq | 0.0376 | 0.9309 | |
| SRP008496 | TNFAIP8 | 25816 | RNAseq | 0.3448 | 0.2183 | |
| SRP064894 | TNFAIP8 | 25816 | RNAseq | 0.2376 | 0.2064 | |
| SRP133303 | TNFAIP8 | 25816 | RNAseq | 0.0721 | 0.7844 | |
| SRP159526 | TNFAIP8 | 25816 | RNAseq | -0.5790 | 0.3546 | |
| SRP193095 | TNFAIP8 | 25816 | RNAseq | -0.2383 | 0.0917 | |
| SRP219564 | TNFAIP8 | 25816 | RNAseq | 0.2526 | 0.5770 | |
| TCGA | TNFAIP8 | 25816 | RNAseq | 0.3115 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNFAIP8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFAIP8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFAIP8 | 25816 | 1 | 13 | 16 | |
| GSE20123 | TNFAIP8 | 25816 | 1 | 13 | 16 | |
| GSE43470 | TNFAIP8 | 25816 | 5 | 6 | 32 | |
| GSE46452 | TNFAIP8 | 25816 | 0 | 27 | 32 | |
| GSE47630 | TNFAIP8 | 25816 | 0 | 21 | 19 | |
| GSE54993 | TNFAIP8 | 25816 | 9 | 1 | 60 | |
| GSE54994 | TNFAIP8 | 25816 | 2 | 14 | 37 | |
| GSE60625 | TNFAIP8 | 25816 | 0 | 0 | 11 | |
| GSE74703 | TNFAIP8 | 25816 | 3 | 5 | 28 | |
| GSE74704 | TNFAIP8 | 25816 | 1 | 7 | 12 | |
| TCGA | TNFAIP8 | 25816 | 2 | 43 | 51 |
Total number of gains: 24; Total number of losses: 150; Total Number of normals: 314.
Somatic mutations of TNFAIP8:
Generating mutation plots.
Highly correlated genes for TNFAIP8:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFAIP8 | STOML2 | 0.750825 | 3 | 0 | 3 |
| TNFAIP8 | PRIM1 | 0.730349 | 3 | 0 | 3 |
| TNFAIP8 | CDC123 | 0.718933 | 3 | 0 | 3 |
| TNFAIP8 | RPP40 | 0.715375 | 3 | 0 | 3 |
| TNFAIP8 | CCDC25 | 0.710688 | 3 | 0 | 3 |
| TNFAIP8 | CDKN1B | 0.692872 | 3 | 0 | 3 |
| TNFAIP8 | ZNF217 | 0.692868 | 3 | 0 | 3 |
| TNFAIP8 | IPMK | 0.691876 | 3 | 0 | 3 |
| TNFAIP8 | CDC27 | 0.690589 | 3 | 0 | 3 |
| TNFAIP8 | HSPA9 | 0.689636 | 4 | 0 | 3 |
| TNFAIP8 | SNX4 | 0.689234 | 3 | 0 | 3 |
| TNFAIP8 | NECAP1 | 0.68807 | 3 | 0 | 3 |
| TNFAIP8 | WDR41 | 0.686677 | 4 | 0 | 3 |
| TNFAIP8 | CLPX | 0.684499 | 4 | 0 | 4 |
| TNFAIP8 | FBXO8 | 0.68266 | 3 | 0 | 3 |
| TNFAIP8 | HSBP1 | 0.679681 | 4 | 0 | 4 |
| TNFAIP8 | LYSMD3 | 0.678659 | 4 | 0 | 3 |
| TNFAIP8 | NAGA | 0.678327 | 3 | 0 | 3 |
| TNFAIP8 | ECHDC1 | 0.677812 | 3 | 0 | 3 |
| TNFAIP8 | CYP4X1 | 0.674188 | 3 | 0 | 3 |
For details and further investigation, click here
