| Full name: membrane bound transcription factor peptidase, site 2 | Alias Symbol: S2P | ||
| Type: protein-coding gene | Cytoband: Xp22.12 | ||
| Entrez ID: 51360 | HGNC ID: HGNC:15455 | Ensembl Gene: ENSG00000012174 | OMIM ID: 300294 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MBTPS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBTPS2 | 51360 | 226760_at | 0.0980 | 0.8394 | |
| GSE20347 | MBTPS2 | 51360 | 206473_at | -0.0433 | 0.5169 | |
| GSE23400 | MBTPS2 | 51360 | 206473_at | -0.0983 | 0.0023 | |
| GSE26886 | MBTPS2 | 51360 | 226760_at | 0.0718 | 0.8179 | |
| GSE29001 | MBTPS2 | 51360 | 206473_at | -0.0595 | 0.7212 | |
| GSE38129 | MBTPS2 | 51360 | 206473_at | -0.0926 | 0.0573 | |
| GSE45670 | MBTPS2 | 51360 | 226760_at | 0.1143 | 0.5750 | |
| GSE53622 | MBTPS2 | 51360 | 19812 | 0.2269 | 0.0036 | |
| GSE53624 | MBTPS2 | 51360 | 19812 | 0.3603 | 0.0003 | |
| GSE63941 | MBTPS2 | 51360 | 226760_at | -0.9658 | 0.1209 | |
| GSE77861 | MBTPS2 | 51360 | 226760_at | 0.3855 | 0.1901 | |
| GSE97050 | MBTPS2 | 51360 | A_23_P114095 | 0.2589 | 0.3463 | |
| SRP007169 | MBTPS2 | 51360 | RNAseq | 0.2277 | 0.6390 | |
| SRP008496 | MBTPS2 | 51360 | RNAseq | 0.2812 | 0.3028 | |
| SRP064894 | MBTPS2 | 51360 | RNAseq | 0.1875 | 0.4009 | |
| SRP133303 | MBTPS2 | 51360 | RNAseq | 0.6514 | 0.0075 | |
| SRP159526 | MBTPS2 | 51360 | RNAseq | 0.5263 | 0.0593 | |
| SRP193095 | MBTPS2 | 51360 | RNAseq | 0.2261 | 0.0726 | |
| SRP219564 | MBTPS2 | 51360 | RNAseq | 0.6816 | 0.1456 | |
| TCGA | MBTPS2 | 51360 | RNAseq | -0.0674 | 0.2665 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MBTPS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MBTPS2:
No record found for this gene.
Somatic mutations of MBTPS2:
Generating mutation plots.
Highly correlated genes for MBTPS2:
Showing top 20/295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBTPS2 | ZNRF3 | 0.768679 | 3 | 0 | 3 |
| MBTPS2 | SPPL2A | 0.755523 | 3 | 0 | 3 |
| MBTPS2 | DHRSX | 0.746658 | 3 | 0 | 3 |
| MBTPS2 | BAG4 | 0.740493 | 4 | 0 | 3 |
| MBTPS2 | ANKS6 | 0.739371 | 3 | 0 | 3 |
| MBTPS2 | LATS1 | 0.736888 | 4 | 0 | 4 |
| MBTPS2 | FH | 0.733686 | 3 | 0 | 3 |
| MBTPS2 | NAE1 | 0.726461 | 4 | 0 | 3 |
| MBTPS2 | ADCYAP1 | 0.72399 | 3 | 0 | 3 |
| MBTPS2 | MRPL36 | 0.720488 | 3 | 0 | 3 |
| MBTPS2 | CLEC2B | 0.720383 | 3 | 0 | 3 |
| MBTPS2 | SH2D3C | 0.718753 | 5 | 0 | 5 |
| MBTPS2 | SEMA3A | 0.712231 | 3 | 0 | 3 |
| MBTPS2 | SULT2A1 | 0.712126 | 3 | 0 | 3 |
| MBTPS2 | GMCL1 | 0.710102 | 4 | 0 | 4 |
| MBTPS2 | SLC6A15 | 0.697213 | 3 | 0 | 3 |
| MBTPS2 | FAM98B | 0.692702 | 5 | 0 | 4 |
| MBTPS2 | METTL23 | 0.689263 | 3 | 0 | 3 |
| MBTPS2 | POLA1 | 0.689173 | 5 | 0 | 5 |
| MBTPS2 | TMEM38B | 0.688886 | 3 | 0 | 3 |
For details and further investigation, click here
