| Full name: small ubiquitin like modifier 3 | Alias Symbol: SMT3A | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 6612 | HGNC ID: HGNC:11124 | Ensembl Gene: ENSG00000184900 | OMIM ID: 602231 |
| Drug and gene relationship at DGIdb | |||
Expression of SUMO3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUMO3 | 6612 | 200740_s_at | 0.5715 | 0.0961 | |
| GSE20347 | SUMO3 | 6612 | 200740_s_at | 0.6100 | 0.0000 | |
| GSE23400 | SUMO3 | 6612 | 200740_s_at | 0.6804 | 0.0000 | |
| GSE26886 | SUMO3 | 6612 | 200740_s_at | -0.3870 | 0.0161 | |
| GSE29001 | SUMO3 | 6612 | 200740_s_at | 0.7481 | 0.0019 | |
| GSE38129 | SUMO3 | 6612 | 200740_s_at | 0.7785 | 0.0000 | |
| GSE45670 | SUMO3 | 6612 | 200740_s_at | 0.3450 | 0.0246 | |
| GSE53622 | SUMO3 | 6612 | 4216 | 0.4459 | 0.0000 | |
| GSE53624 | SUMO3 | 6612 | 4216 | 0.5307 | 0.0000 | |
| GSE63941 | SUMO3 | 6612 | 200740_s_at | 0.3809 | 0.2950 | |
| GSE77861 | SUMO3 | 6612 | 200740_s_at | -0.0899 | 0.7831 | |
| GSE97050 | SUMO3 | 6612 | A_23_P102937 | 0.1616 | 0.5794 | |
| SRP007169 | SUMO3 | 6612 | RNAseq | -0.0660 | 0.8276 | |
| SRP008496 | SUMO3 | 6612 | RNAseq | 0.4595 | 0.0954 | |
| SRP064894 | SUMO3 | 6612 | RNAseq | 0.8130 | 0.0005 | |
| SRP133303 | SUMO3 | 6612 | RNAseq | 0.3511 | 0.0044 | |
| SRP159526 | SUMO3 | 6612 | RNAseq | 0.8828 | 0.0000 | |
| SRP193095 | SUMO3 | 6612 | RNAseq | 0.3962 | 0.0046 | |
| SRP219564 | SUMO3 | 6612 | RNAseq | 0.2803 | 0.3851 | |
| TCGA | SUMO3 | 6612 | RNAseq | 0.1411 | 0.0028 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SUMO3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUMO3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUMO3 | 6612 | 2 | 9 | 19 | |
| GSE20123 | SUMO3 | 6612 | 2 | 9 | 19 | |
| GSE43470 | SUMO3 | 6612 | 0 | 13 | 30 | |
| GSE46452 | SUMO3 | 6612 | 1 | 21 | 37 | |
| GSE47630 | SUMO3 | 6612 | 6 | 17 | 17 | |
| GSE54993 | SUMO3 | 6612 | 8 | 1 | 61 | |
| GSE54994 | SUMO3 | 6612 | 4 | 8 | 41 | |
| GSE60625 | SUMO3 | 6612 | 0 | 0 | 11 | |
| GSE74703 | SUMO3 | 6612 | 0 | 10 | 26 | |
| GSE74704 | SUMO3 | 6612 | 1 | 5 | 14 | |
| TCGA | SUMO3 | 6612 | 9 | 38 | 49 |
Total number of gains: 33; Total number of losses: 131; Total Number of normals: 324.
Somatic mutations of SUMO3:
Generating mutation plots.
Highly correlated genes for SUMO3:
Showing top 20/1208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUMO3 | TATDN2 | 0.846799 | 3 | 0 | 3 |
| SUMO3 | FAM161A | 0.798981 | 3 | 0 | 3 |
| SUMO3 | TTI2 | 0.78524 | 3 | 0 | 3 |
| SUMO3 | COMMD7 | 0.760971 | 3 | 0 | 3 |
| SUMO3 | HPS3 | 0.757546 | 3 | 0 | 3 |
| SUMO3 | CDC42EP1 | 0.755928 | 3 | 0 | 3 |
| SUMO3 | UHRF1BP1 | 0.752806 | 3 | 0 | 3 |
| SUMO3 | CNOT10 | 0.75018 | 3 | 0 | 3 |
| SUMO3 | MRPS11 | 0.748236 | 3 | 0 | 3 |
| SUMO3 | REST | 0.747512 | 3 | 0 | 3 |
| SUMO3 | C2CD2 | 0.745306 | 3 | 0 | 3 |
| SUMO3 | NFXL1 | 0.735097 | 3 | 0 | 3 |
| SUMO3 | DYRK2 | 0.731124 | 3 | 0 | 3 |
| SUMO3 | RWDD4 | 0.719849 | 3 | 0 | 3 |
| SUMO3 | SLBP | 0.717902 | 8 | 0 | 8 |
| SUMO3 | CWF19L1 | 0.715208 | 4 | 0 | 3 |
| SUMO3 | ECT2 | 0.710475 | 8 | 0 | 8 |
| SUMO3 | POLR2K | 0.704377 | 7 | 0 | 7 |
| SUMO3 | WDR70 | 0.70424 | 4 | 0 | 4 |
| SUMO3 | C1orf131 | 0.702394 | 5 | 0 | 5 |
For details and further investigation, click here
