SLBP

 

Full name: stem-loop binding protein Alias Symbol: HBP
Type: protein-coding gene Cytoband: 4p16.3
Entrez ID: 7884 HGNC ID: HGNC:10904 Ensembl Gene: ENSG00000163950 OMIM ID: 602422
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of SLBP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLBP 7884 206052_s_at 0.5898 0.0584
GSE20347 SLBP 7884 206052_s_at 0.4537 0.0075
GSE23400 SLBP 7884 206052_s_at 0.7213 0.0000
GSE26886 SLBP 7884 206052_s_at 0.4237 0.0445
GSE29001 SLBP 7884 206052_s_at 0.6458 0.0944
GSE38129 SLBP 7884 206052_s_at 0.6087 0.0000
GSE45670 SLBP 7884 206052_s_at 0.2871 0.1170
GSE53622 SLBP 7884 973 0.5376 0.0000
GSE53624 SLBP 7884 973 0.5440 0.0000
GSE63941 SLBP 7884 206052_s_at -0.0185 0.9602
GSE77861 SLBP 7884 206052_s_at 0.3138 0.2061
GSE97050 SLBP 7884 A_23_P7101 0.5664 0.1567
SRP007169 SLBP 7884 RNAseq 0.1691 0.6214
SRP008496 SLBP 7884 RNAseq 0.1710 0.4500
SRP064894 SLBP 7884 RNAseq 0.5773 0.0026
SRP133303 SLBP 7884 RNAseq 0.5111 0.0004
SRP159526 SLBP 7884 RNAseq 0.5516 0.0396
SRP193095 SLBP 7884 RNAseq 0.0845 0.4345
SRP219564 SLBP 7884 RNAseq 0.3845 0.2622
TCGA SLBP 7884 RNAseq 0.2366 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SLBP expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLBP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLBP 7884 0 16 14
GSE20123 SLBP 7884 0 16 14
GSE43470 SLBP 7884 1 16 26
GSE46452 SLBP 7884 1 36 22
GSE47630 SLBP 7884 2 19 19
GSE54993 SLBP 7884 11 0 59
GSE54994 SLBP 7884 3 12 38
GSE60625 SLBP 7884 0 0 11
GSE74703 SLBP 7884 1 12 23
GSE74704 SLBP 7884 0 8 12
TCGA SLBP 7884 9 47 40

Total number of gains: 28; Total number of losses: 182; Total Number of normals: 278.  

 

Somatic mutations of SLBP:

 

Generating mutation plots.

 

Highly correlated genes for SLBP:

 

Showing top 20/1838 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLBPMMS22L0.802692303
SLBPPPP2R1B0.763966303
SLBPUHMK10.76181505
SLBPPTGES0.759006404
SLBPABCF30.748484505
SLBPBRMS1L0.739182303
SLBPROMO10.733489303
SLBPCPNE80.730607403
SLBPWDR750.726535404
SLBPLRRC580.72492403
SLBPSLC36A40.724319303
SLBPABCB100.723109404
SLBPPAICS0.72280311011
SLBPUBR70.720312606
SLBPMEX3B0.720134303
SLBPSUMO30.717902808
SLBPDBF40.71668611011
SLBPTOPBP10.713369907
SLBPFLVCR10.71141606
SLBPGMPS0.711117908

For details and further investigation, click here