| Full name: synapse defective Rho GTPase homolog 2 | Alias Symbol: FLJ13815 | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 84144 | HGNC ID: HGNC:25841 | Ensembl Gene: ENSG00000097096 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SYDE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYDE2 | 84144 | 1560101_at | 0.0872 | 0.9243 | |
| GSE26886 | SYDE2 | 84144 | 1560101_at | 0.2644 | 0.1995 | |
| GSE45670 | SYDE2 | 84144 | 1560101_at | -0.1137 | 0.4449 | |
| GSE53622 | SYDE2 | 84144 | 8046 | -0.5112 | 0.0003 | |
| GSE53624 | SYDE2 | 84144 | 8046 | -0.1600 | 0.0994 | |
| GSE63941 | SYDE2 | 84144 | 1560101_at | -0.2091 | 0.7370 | |
| GSE77861 | SYDE2 | 84144 | 1560101_at | -0.0721 | 0.5403 | |
| GSE97050 | SYDE2 | 84144 | A_33_P3412767 | -0.6331 | 0.1826 | |
| SRP007169 | SYDE2 | 84144 | RNAseq | 0.5991 | 0.3858 | |
| SRP008496 | SYDE2 | 84144 | RNAseq | 0.5290 | 0.2462 | |
| SRP133303 | SYDE2 | 84144 | RNAseq | 0.1919 | 0.6236 | |
| SRP159526 | SYDE2 | 84144 | RNAseq | -0.3175 | 0.4190 | |
| SRP193095 | SYDE2 | 84144 | RNAseq | -0.6192 | 0.0098 | |
| TCGA | SYDE2 | 84144 | RNAseq | -0.6481 | 0.0074 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYDE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYDE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYDE2 | 84144 | 0 | 8 | 22 | |
| GSE20123 | SYDE2 | 84144 | 0 | 8 | 22 | |
| GSE43470 | SYDE2 | 84144 | 2 | 2 | 39 | |
| GSE46452 | SYDE2 | 84144 | 0 | 1 | 58 | |
| GSE47630 | SYDE2 | 84144 | 8 | 5 | 27 | |
| GSE54993 | SYDE2 | 84144 | 0 | 0 | 70 | |
| GSE54994 | SYDE2 | 84144 | 6 | 3 | 44 | |
| GSE60625 | SYDE2 | 84144 | 0 | 0 | 11 | |
| GSE74703 | SYDE2 | 84144 | 1 | 2 | 33 | |
| GSE74704 | SYDE2 | 84144 | 0 | 5 | 15 | |
| TCGA | SYDE2 | 84144 | 7 | 23 | 66 |
Total number of gains: 24; Total number of losses: 57; Total Number of normals: 407.
Somatic mutations of SYDE2:
Generating mutation plots.
Highly correlated genes for SYDE2:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYDE2 | ZNF483 | 0.739859 | 3 | 0 | 3 |
| SYDE2 | REPS2 | 0.702054 | 3 | 0 | 3 |
| SYDE2 | ADCY5 | 0.648415 | 3 | 0 | 3 |
| SYDE2 | VIPR2 | 0.639299 | 3 | 0 | 3 |
| SYDE2 | ZNF444 | 0.638925 | 3 | 0 | 3 |
| SYDE2 | SLC8A1 | 0.630724 | 4 | 0 | 3 |
| SYDE2 | VAMP4 | 0.628744 | 3 | 0 | 3 |
| SYDE2 | PTBP2 | 0.623443 | 3 | 0 | 3 |
| SYDE2 | DISP1 | 0.616066 | 4 | 0 | 3 |
| SYDE2 | PPOX | 0.614866 | 3 | 0 | 3 |
| SYDE2 | NPY | 0.599367 | 5 | 0 | 3 |
| SYDE2 | BST1 | 0.585765 | 4 | 0 | 3 |
| SYDE2 | ZFP2 | 0.585167 | 4 | 0 | 3 |
| SYDE2 | UBE2D4 | 0.57937 | 4 | 0 | 3 |
| SYDE2 | SNTB1 | 0.568495 | 3 | 0 | 3 |
| SYDE2 | STMN2 | 0.568295 | 4 | 0 | 3 |
| SYDE2 | BMPR1B | 0.565831 | 5 | 0 | 3 |
| SYDE2 | ZNF501 | 0.565005 | 5 | 0 | 3 |
| SYDE2 | HECTD2 | 0.559789 | 5 | 0 | 3 |
| SYDE2 | CDHR3 | 0.553364 | 6 | 0 | 3 |
For details and further investigation, click here
