| Full name: cell division cycle associated 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 113130 | HGNC ID: HGNC:14626 | Ensembl Gene: ENSG00000146670 | OMIM ID: 609374 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CDCA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDCA5 | 113130 | 224753_at | 1.6561 | 0.0194 | |
| GSE26886 | CDCA5 | 113130 | 224753_at | 0.7054 | 0.0034 | |
| GSE45670 | CDCA5 | 113130 | 224753_at | 1.5567 | 0.0000 | |
| GSE53622 | CDCA5 | 113130 | 60556 | 2.0469 | 0.0000 | |
| GSE53624 | CDCA5 | 113130 | 60556 | 2.5614 | 0.0000 | |
| GSE63941 | CDCA5 | 113130 | 224753_at | 2.6807 | 0.0003 | |
| GSE77861 | CDCA5 | 113130 | 224753_at | 0.9698 | 0.0036 | |
| GSE97050 | CDCA5 | 113130 | A_33_P3277575 | 0.3346 | 0.3585 | |
| SRP007169 | CDCA5 | 113130 | RNAseq | 2.6280 | 0.0000 | |
| SRP008496 | CDCA5 | 113130 | RNAseq | 1.9490 | 0.0000 | |
| SRP064894 | CDCA5 | 113130 | RNAseq | 2.0316 | 0.0000 | |
| SRP133303 | CDCA5 | 113130 | RNAseq | 2.2765 | 0.0000 | |
| SRP159526 | CDCA5 | 113130 | RNAseq | 2.0623 | 0.0000 | |
| SRP193095 | CDCA5 | 113130 | RNAseq | 1.5497 | 0.0000 | |
| SRP219564 | CDCA5 | 113130 | RNAseq | 2.0046 | 0.0025 | |
| TCGA | CDCA5 | 113130 | RNAseq | 1.3261 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by CDCA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDCA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDCA5 | 113130 | 7 | 6 | 17 | |
| GSE20123 | CDCA5 | 113130 | 7 | 6 | 17 | |
| GSE43470 | CDCA5 | 113130 | 2 | 3 | 38 | |
| GSE46452 | CDCA5 | 113130 | 10 | 4 | 45 | |
| GSE47630 | CDCA5 | 113130 | 5 | 6 | 29 | |
| GSE54993 | CDCA5 | 113130 | 3 | 0 | 67 | |
| GSE54994 | CDCA5 | 113130 | 6 | 5 | 42 | |
| GSE60625 | CDCA5 | 113130 | 0 | 3 | 8 | |
| GSE74703 | CDCA5 | 113130 | 2 | 1 | 33 | |
| GSE74704 | CDCA5 | 113130 | 5 | 4 | 11 | |
| TCGA | CDCA5 | 113130 | 23 | 7 | 66 |
Total number of gains: 70; Total number of losses: 45; Total Number of normals: 373.
Somatic mutations of CDCA5:
Generating mutation plots.
Highly correlated genes for CDCA5:
Showing top 20/747 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDCA5 | RAD51 | 0.88853 | 8 | 0 | 8 |
| CDCA5 | CDC6 | 0.883996 | 6 | 0 | 6 |
| CDCA5 | FEN1 | 0.86585 | 7 | 0 | 7 |
| CDCA5 | CDC45 | 0.864059 | 7 | 0 | 7 |
| CDCA5 | MYBL2 | 0.837969 | 7 | 0 | 7 |
| CDCA5 | KNSTRN | 0.829128 | 7 | 0 | 7 |
| CDCA5 | TPX2 | 0.823629 | 8 | 0 | 7 |
| CDCA5 | MEST | 0.823628 | 5 | 0 | 5 |
| CDCA5 | MTFR2 | 0.822055 | 7 | 0 | 7 |
| CDCA5 | UBE2T | 0.82191 | 8 | 0 | 7 |
| CDCA5 | TRIP13 | 0.821623 | 8 | 0 | 8 |
| CDCA5 | AURKB | 0.821576 | 8 | 0 | 8 |
| CDCA5 | CDK1 | 0.817466 | 7 | 0 | 7 |
| CDCA5 | CDC20 | 0.816892 | 9 | 0 | 9 |
| CDCA5 | NUDT1 | 0.814336 | 7 | 0 | 7 |
| CDCA5 | PNPT1 | 0.813036 | 5 | 0 | 5 |
| CDCA5 | MELK | 0.8085 | 7 | 0 | 7 |
| CDCA5 | KIF4A | 0.806867 | 9 | 0 | 8 |
| CDCA5 | KIF2C | 0.80533 | 8 | 0 | 7 |
| CDCA5 | ORC6 | 0.80299 | 8 | 0 | 8 |
For details and further investigation, click here
