| Full name: CD79b molecule | Alias Symbol: B29 | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 974 | HGNC ID: HGNC:1699 | Ensembl Gene: ENSG00000007312 | OMIM ID: 147245 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
CD79B involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04662 | B cell receptor signaling pathway |
Expression of CD79B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD79B | 974 | 205297_s_at | 0.1915 | 0.8572 | |
| GSE20347 | CD79B | 974 | 205297_s_at | -0.0228 | 0.8537 | |
| GSE23400 | CD79B | 974 | 205297_s_at | -0.2292 | 0.0000 | |
| GSE26886 | CD79B | 974 | 1555748_x_at | 0.0954 | 0.5213 | |
| GSE29001 | CD79B | 974 | 205297_s_at | -0.1491 | 0.2036 | |
| GSE38129 | CD79B | 974 | 205297_s_at | -0.2426 | 0.1643 | |
| GSE45670 | CD79B | 974 | 1555748_x_at | -0.0853 | 0.3950 | |
| GSE53622 | CD79B | 974 | 8698 | -0.9643 | 0.0002 | |
| GSE53624 | CD79B | 974 | 8698 | -1.2470 | 0.0000 | |
| GSE63941 | CD79B | 974 | 1555748_x_at | 0.1229 | 0.4533 | |
| GSE77861 | CD79B | 974 | 1555748_x_at | -0.0868 | 0.6377 | |
| GSE97050 | CD79B | 974 | A_23_P207201 | 0.7795 | 0.1852 | |
| SRP064894 | CD79B | 974 | RNAseq | 0.6246 | 0.1829 | |
| SRP133303 | CD79B | 974 | RNAseq | -1.1842 | 0.0193 | |
| SRP159526 | CD79B | 974 | RNAseq | -1.7033 | 0.0589 | |
| SRP219564 | CD79B | 974 | RNAseq | 0.1153 | 0.7833 | |
| TCGA | CD79B | 974 | RNAseq | -0.5633 | 0.1250 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CD79B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD79B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD79B | 974 | 3 | 1 | 26 | |
| GSE20123 | CD79B | 974 | 3 | 1 | 26 | |
| GSE43470 | CD79B | 974 | 4 | 0 | 39 | |
| GSE46452 | CD79B | 974 | 31 | 0 | 28 | |
| GSE47630 | CD79B | 974 | 7 | 1 | 32 | |
| GSE54993 | CD79B | 974 | 2 | 5 | 63 | |
| GSE54994 | CD79B | 974 | 9 | 4 | 40 | |
| GSE60625 | CD79B | 974 | 4 | 0 | 7 | |
| GSE74703 | CD79B | 974 | 4 | 0 | 32 | |
| GSE74704 | CD79B | 974 | 3 | 1 | 16 | |
| TCGA | CD79B | 974 | 30 | 8 | 58 |
Total number of gains: 100; Total number of losses: 21; Total Number of normals: 367.
Somatic mutations of CD79B:
Generating mutation plots.
Highly correlated genes for CD79B:
Showing top 20/452 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD79B | BTLA | 0.8586 | 4 | 0 | 4 |
| CD79B | FCRLA | 0.841271 | 5 | 0 | 5 |
| CD79B | GAPT | 0.817725 | 4 | 0 | 4 |
| CD79B | TNFAIP8L2 | 0.794462 | 4 | 0 | 4 |
| CD79B | TAGAP | 0.788401 | 5 | 0 | 5 |
| CD79B | CD19 | 0.774987 | 9 | 0 | 9 |
| CD79B | LINC01215 | 0.774953 | 4 | 0 | 4 |
| CD79B | XBP1 | 0.77051 | 3 | 0 | 3 |
| CD79B | SNX20 | 0.768383 | 5 | 0 | 5 |
| CD79B | GIMAP1 | 0.76754 | 5 | 0 | 5 |
| CD79B | POU2AF1 | 0.766186 | 3 | 0 | 3 |
| CD79B | RHOH | 0.751197 | 8 | 0 | 8 |
| CD79B | TCL1A | 0.748976 | 6 | 0 | 6 |
| CD79B | CD180 | 0.746499 | 7 | 0 | 7 |
| CD79B | TIFAB | 0.742066 | 3 | 0 | 3 |
| CD79B | CD22 | 0.738473 | 8 | 0 | 7 |
| CD79B | CLEC17A | 0.737503 | 3 | 0 | 3 |
| CD79B | SUSD3 | 0.732196 | 5 | 0 | 5 |
| CD79B | C16orf58 | 0.727599 | 3 | 0 | 3 |
| CD79B | CD163L1 | 0.722355 | 3 | 0 | 3 |
For details and further investigation, click here
