| Full name: TBC1 domain family member 2B | Alias Symbol: KIAA1055 | ||
| Type: protein-coding gene | Cytoband: 15q24.3-q25.1 | ||
| Entrez ID: 23102 | HGNC ID: HGNC:29183 | Ensembl Gene: ENSG00000167202 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D2B | 23102 | 212796_s_at | 0.2615 | 0.5344 | |
| GSE20347 | TBC1D2B | 23102 | 212796_s_at | 0.2589 | 0.0554 | |
| GSE23400 | TBC1D2B | 23102 | 212796_s_at | -0.0307 | 0.6188 | |
| GSE26886 | TBC1D2B | 23102 | 212796_s_at | 0.2784 | 0.0556 | |
| GSE29001 | TBC1D2B | 23102 | 212796_s_at | 0.3886 | 0.0866 | |
| GSE38129 | TBC1D2B | 23102 | 212796_s_at | 0.0227 | 0.8956 | |
| GSE45670 | TBC1D2B | 23102 | 212796_s_at | -0.2695 | 0.1204 | |
| GSE63941 | TBC1D2B | 23102 | 212796_s_at | -1.4783 | 0.0057 | |
| GSE77861 | TBC1D2B | 23102 | 212796_s_at | 0.0537 | 0.7763 | |
| GSE97050 | TBC1D2B | 23102 | A_23_P396666 | 0.0107 | 0.9729 | |
| SRP007169 | TBC1D2B | 23102 | RNAseq | 1.0094 | 0.0170 | |
| SRP008496 | TBC1D2B | 23102 | RNAseq | 0.9553 | 0.0028 | |
| SRP064894 | TBC1D2B | 23102 | RNAseq | 0.5276 | 0.0062 | |
| SRP133303 | TBC1D2B | 23102 | RNAseq | 0.1092 | 0.4173 | |
| SRP159526 | TBC1D2B | 23102 | RNAseq | 0.2269 | 0.3574 | |
| SRP193095 | TBC1D2B | 23102 | RNAseq | 0.3267 | 0.0143 | |
| SRP219564 | TBC1D2B | 23102 | RNAseq | 0.4613 | 0.0714 | |
| TCGA | TBC1D2B | 23102 | RNAseq | -0.1523 | 0.0013 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by TBC1D2B expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D2B | 23102 | 7 | 1 | 22 | |
| GSE20123 | TBC1D2B | 23102 | 7 | 1 | 22 | |
| GSE43470 | TBC1D2B | 23102 | 4 | 5 | 34 | |
| GSE46452 | TBC1D2B | 23102 | 3 | 7 | 49 | |
| GSE47630 | TBC1D2B | 23102 | 8 | 10 | 22 | |
| GSE54993 | TBC1D2B | 23102 | 5 | 6 | 59 | |
| GSE54994 | TBC1D2B | 23102 | 5 | 6 | 42 | |
| GSE60625 | TBC1D2B | 23102 | 4 | 0 | 7 | |
| GSE74703 | TBC1D2B | 23102 | 4 | 3 | 29 | |
| GSE74704 | TBC1D2B | 23102 | 3 | 1 | 16 | |
| TCGA | TBC1D2B | 23102 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of TBC1D2B:
Generating mutation plots.
Highly correlated genes for TBC1D2B:
Showing top 20/649 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D2B | SOX18 | 0.765549 | 3 | 0 | 3 |
| TBC1D2B | TNFRSF19 | 0.764725 | 3 | 0 | 3 |
| TBC1D2B | STOM | 0.735396 | 3 | 0 | 3 |
| TBC1D2B | VPS26B | 0.723601 | 3 | 0 | 3 |
| TBC1D2B | LRP4 | 0.719069 | 3 | 0 | 3 |
| TBC1D2B | MGAT5 | 0.71192 | 3 | 0 | 3 |
| TBC1D2B | GLIPR2 | 0.711177 | 4 | 0 | 4 |
| TBC1D2B | ZNF521 | 0.706789 | 3 | 0 | 3 |
| TBC1D2B | CYTH3 | 0.702203 | 4 | 0 | 4 |
| TBC1D2B | B3GNT9 | 0.698143 | 3 | 0 | 3 |
| TBC1D2B | CLMP | 0.695581 | 3 | 0 | 3 |
| TBC1D2B | KHDRBS1 | 0.690542 | 3 | 0 | 3 |
| TBC1D2B | CNRIP1 | 0.685102 | 3 | 0 | 3 |
| TBC1D2B | ARMCX2 | 0.682589 | 5 | 0 | 5 |
| TBC1D2B | RPS27L | 0.681342 | 6 | 0 | 5 |
| TBC1D2B | DEGS1 | 0.680574 | 4 | 0 | 3 |
| TBC1D2B | MAP3K3 | 0.679452 | 3 | 0 | 3 |
| TBC1D2B | SVEP1 | 0.674027 | 4 | 0 | 4 |
| TBC1D2B | RASGRP3 | 0.671891 | 4 | 0 | 3 |
| TBC1D2B | FIBIN | 0.670174 | 3 | 0 | 3 |
For details and further investigation, click here
