| Full name: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase | Alias Symbol: GNT-V|MGAT5A | ||
| Type: protein-coding gene | Cytoband: 2q21.2-q21.3 | ||
| Entrez ID: 4249 | HGNC ID: HGNC:7049 | Ensembl Gene: ENSG00000152127 | OMIM ID: 601774 |
| Drug and gene relationship at DGIdb | |||
Expression of MGAT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MGAT5 | 4249 | 212098_at | 0.5253 | 0.3681 | |
| GSE20347 | MGAT5 | 4249 | 212098_at | 0.2663 | 0.0632 | |
| GSE23400 | MGAT5 | 4249 | 212098_at | 0.0438 | 0.5705 | |
| GSE26886 | MGAT5 | 4249 | 212098_at | 0.1704 | 0.4477 | |
| GSE29001 | MGAT5 | 4249 | 212098_at | 0.0594 | 0.9020 | |
| GSE38129 | MGAT5 | 4249 | 212098_at | 0.4061 | 0.0587 | |
| GSE45670 | MGAT5 | 4249 | 212098_at | 0.2804 | 0.2224 | |
| GSE53622 | MGAT5 | 4249 | 14560 | 0.2366 | 0.0214 | |
| GSE53624 | MGAT5 | 4249 | 14560 | 0.3284 | 0.0000 | |
| GSE63941 | MGAT5 | 4249 | 212098_at | -2.3553 | 0.0003 | |
| GSE77861 | MGAT5 | 4249 | 212098_at | 0.8133 | 0.0658 | |
| GSE97050 | MGAT5 | 4249 | A_33_P3255209 | 0.0945 | 0.6737 | |
| SRP007169 | MGAT5 | 4249 | RNAseq | 0.5636 | 0.1276 | |
| SRP008496 | MGAT5 | 4249 | RNAseq | 0.7017 | 0.0337 | |
| SRP064894 | MGAT5 | 4249 | RNAseq | 0.1072 | 0.4485 | |
| SRP133303 | MGAT5 | 4249 | RNAseq | 0.0234 | 0.8280 | |
| SRP159526 | MGAT5 | 4249 | RNAseq | 0.4804 | 0.0913 | |
| SRP193095 | MGAT5 | 4249 | RNAseq | -0.0691 | 0.7245 | |
| SRP219564 | MGAT5 | 4249 | RNAseq | -0.2541 | 0.5493 | |
| TCGA | MGAT5 | 4249 | RNAseq | -0.3027 | 0.0023 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MGAT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MGAT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MGAT5 | 4249 | 2 | 4 | 24 | |
| GSE20123 | MGAT5 | 4249 | 2 | 4 | 24 | |
| GSE43470 | MGAT5 | 4249 | 2 | 1 | 40 | |
| GSE46452 | MGAT5 | 4249 | 1 | 4 | 54 | |
| GSE47630 | MGAT5 | 4249 | 5 | 2 | 33 | |
| GSE54993 | MGAT5 | 4249 | 0 | 6 | 64 | |
| GSE54994 | MGAT5 | 4249 | 9 | 0 | 44 | |
| GSE60625 | MGAT5 | 4249 | 0 | 3 | 8 | |
| GSE74703 | MGAT5 | 4249 | 2 | 1 | 33 | |
| GSE74704 | MGAT5 | 4249 | 1 | 1 | 18 | |
| TCGA | MGAT5 | 4249 | 22 | 11 | 63 |
Total number of gains: 46; Total number of losses: 37; Total Number of normals: 405.
Somatic mutations of MGAT5:
Generating mutation plots.
Highly correlated genes for MGAT5:
Showing top 20/636 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MGAT5 | ANTXR2 | 0.792973 | 3 | 0 | 3 |
| MGAT5 | G0S2 | 0.788149 | 3 | 0 | 3 |
| MGAT5 | HMCN1 | 0.774572 | 3 | 0 | 3 |
| MGAT5 | RSRC2 | 0.771927 | 3 | 0 | 3 |
| MGAT5 | DPP4 | 0.770881 | 3 | 0 | 3 |
| MGAT5 | HAS2 | 0.765005 | 4 | 0 | 4 |
| MGAT5 | AIDA | 0.763937 | 3 | 0 | 3 |
| MGAT5 | A2M | 0.761874 | 3 | 0 | 3 |
| MGAT5 | TNFAIP6 | 0.761198 | 4 | 0 | 4 |
| MGAT5 | RFTN2 | 0.756552 | 3 | 0 | 3 |
| MGAT5 | MPP1 | 0.754499 | 3 | 0 | 3 |
| MGAT5 | ZNF25 | 0.751134 | 3 | 0 | 3 |
| MGAT5 | CCL8 | 0.749482 | 3 | 0 | 3 |
| MGAT5 | BMP4 | 0.749416 | 3 | 0 | 3 |
| MGAT5 | BMPR2 | 0.748418 | 4 | 0 | 3 |
| MGAT5 | NBR1 | 0.746114 | 3 | 0 | 3 |
| MGAT5 | CCS | 0.739962 | 3 | 0 | 3 |
| MGAT5 | TM2D2 | 0.736126 | 3 | 0 | 3 |
| MGAT5 | BCL2A1 | 0.735267 | 4 | 0 | 3 |
| MGAT5 | TNFRSF19 | 0.734799 | 3 | 0 | 3 |
For details and further investigation, click here
