| Full name: ribosomal protein S27 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 51065 | HGNC ID: HGNC:18476 | Ensembl Gene: ENSG00000185088 | OMIM ID: 612055 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS27L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS27L | 51065 | 218007_s_at | -0.4289 | 0.2333 | |
| GSE20347 | RPS27L | 51065 | 218007_s_at | 0.1896 | 0.3186 | |
| GSE23400 | RPS27L | 51065 | 218007_s_at | 0.0440 | 0.7251 | |
| GSE26886 | RPS27L | 51065 | 218007_s_at | 0.5480 | 0.0405 | |
| GSE29001 | RPS27L | 51065 | 218007_s_at | -0.1499 | 0.6260 | |
| GSE38129 | RPS27L | 51065 | 218007_s_at | 0.0196 | 0.9236 | |
| GSE45670 | RPS27L | 51065 | 218007_s_at | -0.3748 | 0.0170 | |
| GSE53622 | RPS27L | 51065 | 154846 | -0.1038 | 0.1772 | |
| GSE53624 | RPS27L | 51065 | 154846 | 0.0017 | 0.9830 | |
| GSE63941 | RPS27L | 51065 | 218007_s_at | -2.1651 | 0.0003 | |
| GSE77861 | RPS27L | 51065 | 218007_s_at | -0.0155 | 0.9619 | |
| GSE97050 | RPS27L | 51065 | A_23_P14734 | -0.3732 | 0.1550 | |
| SRP007169 | RPS27L | 51065 | RNAseq | -0.1356 | 0.7121 | |
| SRP008496 | RPS27L | 51065 | RNAseq | -0.0607 | 0.7560 | |
| SRP064894 | RPS27L | 51065 | RNAseq | 0.1384 | 0.6103 | |
| SRP133303 | RPS27L | 51065 | RNAseq | 0.1281 | 0.3913 | |
| SRP159526 | RPS27L | 51065 | RNAseq | -0.3589 | 0.2430 | |
| SRP193095 | RPS27L | 51065 | RNAseq | -0.3906 | 0.0030 | |
| SRP219564 | RPS27L | 51065 | RNAseq | -0.2084 | 0.6665 | |
| TCGA | RPS27L | 51065 | RNAseq | -0.2880 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPS27L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS27L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS27L | 51065 | 8 | 2 | 20 | |
| GSE20123 | RPS27L | 51065 | 8 | 2 | 20 | |
| GSE43470 | RPS27L | 51065 | 4 | 6 | 33 | |
| GSE46452 | RPS27L | 51065 | 3 | 7 | 49 | |
| GSE47630 | RPS27L | 51065 | 8 | 10 | 22 | |
| GSE54993 | RPS27L | 51065 | 5 | 6 | 59 | |
| GSE54994 | RPS27L | 51065 | 6 | 8 | 39 | |
| GSE60625 | RPS27L | 51065 | 4 | 0 | 7 | |
| GSE74703 | RPS27L | 51065 | 4 | 3 | 29 | |
| GSE74704 | RPS27L | 51065 | 4 | 2 | 14 | |
| TCGA | RPS27L | 51065 | 10 | 17 | 69 |
Total number of gains: 64; Total number of losses: 63; Total Number of normals: 361.
Somatic mutations of RPS27L:
Generating mutation plots.
Highly correlated genes for RPS27L:
Showing top 20/865 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS27L | CYP4V2 | 0.775177 | 3 | 0 | 3 |
| RPS27L | ANPEP | 0.770314 | 3 | 0 | 3 |
| RPS27L | RCBTB2 | 0.752869 | 3 | 0 | 3 |
| RPS27L | CD99L2 | 0.745397 | 4 | 0 | 4 |
| RPS27L | PDCD7 | 0.738193 | 3 | 0 | 3 |
| RPS27L | CD59 | 0.736821 | 3 | 0 | 3 |
| RPS27L | FNDC5 | 0.71955 | 3 | 0 | 3 |
| RPS27L | ZDHHC4 | 0.717776 | 3 | 0 | 3 |
| RPS27L | ZFAND2A | 0.714263 | 3 | 0 | 3 |
| RPS27L | ALPK3 | 0.714232 | 3 | 0 | 3 |
| RPS27L | TMSB4Y | 0.70698 | 3 | 0 | 3 |
| RPS27L | MRC2 | 0.706976 | 4 | 0 | 4 |
| RPS27L | PTPN21 | 0.704093 | 4 | 0 | 3 |
| RPS27L | RHOJ | 0.703897 | 4 | 0 | 4 |
| RPS27L | STOML1 | 0.701078 | 4 | 0 | 3 |
| RPS27L | MXI1 | 0.698592 | 3 | 0 | 3 |
| RPS27L | TNFRSF10D | 0.698536 | 3 | 0 | 3 |
| RPS27L | ROR1 | 0.697003 | 4 | 0 | 4 |
| RPS27L | IGIP | 0.694334 | 5 | 0 | 4 |
| RPS27L | C9orf47 | 0.694089 | 3 | 0 | 3 |
For details and further investigation, click here
