| Full name: TDP-glucose 4,6-dehydratase | Alias Symbol: TDPGD|SDR2E1 | ||
| Type: protein-coding gene | Cytoband: 13q32.1 | ||
| Entrez ID: 23483 | HGNC ID: HGNC:20324 | Ensembl Gene: ENSG00000088451 | OMIM ID: 616146 |
| Drug and gene relationship at DGIdb | |||
Expression of TGDS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGDS | 23483 | 208249_s_at | 0.0150 | 0.9742 | |
| GSE20347 | TGDS | 23483 | 208249_s_at | 0.2512 | 0.1289 | |
| GSE23400 | TGDS | 23483 | 208249_s_at | 0.1698 | 0.0220 | |
| GSE26886 | TGDS | 23483 | 208249_s_at | 0.5439 | 0.0283 | |
| GSE29001 | TGDS | 23483 | 208249_s_at | 0.0257 | 0.9478 | |
| GSE38129 | TGDS | 23483 | 208249_s_at | 0.3412 | 0.0017 | |
| GSE45670 | TGDS | 23483 | 208249_s_at | 0.2134 | 0.1619 | |
| GSE53622 | TGDS | 23483 | 120952 | 0.0598 | 0.5947 | |
| GSE53624 | TGDS | 23483 | 87538 | 0.2002 | 0.0325 | |
| GSE63941 | TGDS | 23483 | 208249_s_at | 0.3402 | 0.5458 | |
| GSE77861 | TGDS | 23483 | 208249_s_at | 0.3128 | 0.3282 | |
| GSE97050 | TGDS | 23483 | A_23_P65217 | 0.0755 | 0.8194 | |
| SRP007169 | TGDS | 23483 | RNAseq | 0.5942 | 0.1334 | |
| SRP008496 | TGDS | 23483 | RNAseq | 0.6426 | 0.0719 | |
| SRP064894 | TGDS | 23483 | RNAseq | 0.1581 | 0.4482 | |
| SRP133303 | TGDS | 23483 | RNAseq | 0.2824 | 0.1116 | |
| SRP159526 | TGDS | 23483 | RNAseq | -0.0093 | 0.9758 | |
| SRP193095 | TGDS | 23483 | RNAseq | -0.3280 | 0.0118 | |
| SRP219564 | TGDS | 23483 | RNAseq | 0.2974 | 0.3908 | |
| TCGA | TGDS | 23483 | RNAseq | 0.0390 | 0.5400 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TGDS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGDS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGDS | 23483 | 4 | 9 | 17 | |
| GSE20123 | TGDS | 23483 | 4 | 8 | 18 | |
| GSE43470 | TGDS | 23483 | 2 | 12 | 29 | |
| GSE46452 | TGDS | 23483 | 0 | 32 | 27 | |
| GSE47630 | TGDS | 23483 | 3 | 27 | 10 | |
| GSE54993 | TGDS | 23483 | 11 | 3 | 56 | |
| GSE54994 | TGDS | 23483 | 3 | 14 | 36 | |
| GSE60625 | TGDS | 23483 | 0 | 3 | 8 | |
| GSE74703 | TGDS | 23483 | 2 | 10 | 24 | |
| GSE74704 | TGDS | 23483 | 2 | 8 | 10 | |
| TCGA | TGDS | 23483 | 14 | 33 | 49 |
Total number of gains: 45; Total number of losses: 159; Total Number of normals: 284.
Somatic mutations of TGDS:
Generating mutation plots.
Highly correlated genes for TGDS:
Showing top 20/814 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGDS | TTC30B | 0.836476 | 3 | 0 | 3 |
| TGDS | ACBD5 | 0.8004 | 3 | 0 | 3 |
| TGDS | ATP6V1G1 | 0.781605 | 3 | 0 | 3 |
| TGDS | LACTB | 0.781023 | 3 | 0 | 3 |
| TGDS | SLC39A9 | 0.756339 | 3 | 0 | 3 |
| TGDS | POLG | 0.739492 | 3 | 0 | 3 |
| TGDS | SGTB | 0.737163 | 3 | 0 | 3 |
| TGDS | EID2 | 0.733866 | 3 | 0 | 3 |
| TGDS | ZNF260 | 0.726512 | 3 | 0 | 3 |
| TGDS | BIVM | 0.713383 | 5 | 0 | 5 |
| TGDS | TMEM65 | 0.70867 | 3 | 0 | 3 |
| TGDS | TM2D2 | 0.707615 | 3 | 0 | 3 |
| TGDS | SFT2D3 | 0.702493 | 4 | 0 | 3 |
| TGDS | TRAF3 | 0.699878 | 3 | 0 | 3 |
| TGDS | XXYLT1 | 0.699066 | 3 | 0 | 3 |
| TGDS | ESCO1 | 0.697304 | 4 | 0 | 3 |
| TGDS | PPP1R8 | 0.697166 | 4 | 0 | 3 |
| TGDS | HOXD8 | 0.696185 | 3 | 0 | 3 |
| TGDS | VANGL1 | 0.695382 | 4 | 0 | 3 |
| TGDS | RRM2B | 0.69485 | 4 | 0 | 4 |
For details and further investigation, click here
