VANGL1

 

Full name: VANGL planar cell polarity protein 1 Alias Symbol: STB2
Type: protein-coding gene Cytoband: 1p13.1
Entrez ID: 81839 HGNC ID: HGNC:15512 Ensembl Gene: ENSG00000173218 OMIM ID: 610132
Drug and gene relationship at DGIdb

 

VANGL1 involved pathways:

KEGG pathway Description View
hsa04310Wnt signaling pathway

 

Expression of VANGL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 VANGL1 81839 229997_at 0.3394 0.5573
GSE20347 VANGL1 81839 219330_at 0.1658 0.4056
GSE23400 VANGL1 81839 219330_at 0.5213 0.0000
GSE26886 VANGL1 81839 229997_at 0.2638 0.2489
GSE29001 VANGL1 81839 219330_at 0.6333 0.0297
GSE38129 VANGL1 81839 219330_at 0.6620 0.0002
GSE45670 VANGL1 81839 229997_at 0.2042 0.1985
GSE53622 VANGL1 81839 52282 0.1911 0.0488
GSE53624 VANGL1 81839 52282 0.3701 0.0000
GSE63941 VANGL1 81839 229997_at 1.0754 0.0638
GSE77861 VANGL1 81839 229997_at 0.2236 0.4737
GSE97050 VANGL1 81839 A_24_P199655 0.1037 0.7594
SRP007169 VANGL1 81839 RNAseq 0.0930 0.8462
SRP008496 VANGL1 81839 RNAseq 0.1509 0.6379
SRP064894 VANGL1 81839 RNAseq 0.3940 0.0381
SRP133303 VANGL1 81839 RNAseq 0.2564 0.1455
SRP159526 VANGL1 81839 RNAseq -0.2795 0.3298
SRP193095 VANGL1 81839 RNAseq 0.1893 0.1901
SRP219564 VANGL1 81839 RNAseq 0.1246 0.8334
TCGA VANGL1 81839 RNAseq 0.2124 0.0078

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by VANGL1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of VANGL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 VANGL1 81839 0 9 21
GSE20123 VANGL1 81839 0 9 21
GSE43470 VANGL1 81839 0 8 35
GSE46452 VANGL1 81839 2 1 56
GSE47630 VANGL1 81839 9 5 26
GSE54993 VANGL1 81839 0 1 69
GSE54994 VANGL1 81839 8 3 42
GSE60625 VANGL1 81839 0 0 11
GSE74703 VANGL1 81839 0 7 29
GSE74704 VANGL1 81839 0 5 15
TCGA VANGL1 81839 13 29 54

Total number of gains: 32; Total number of losses: 77; Total Number of normals: 379.  

 

Somatic mutations of VANGL1:

 

Generating mutation plots.

 

Highly correlated genes for VANGL1:

 

Showing top 20/720 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
VANGL1NFKBID0.754645303
VANGL1TMEM600.751534303
VANGL1TMEM170A0.737748303
VANGL1SPCS20.724907303
VANGL1FRMD60.719845303
VANGL1RB10.715425303
VANGL1RPUSD30.709248303
VANGL1CCDC590.698785303
VANGL1PTK20.696919403
VANGL1RNF40.696279404
VANGL1TGDS0.695382403
VANGL1SFT2D30.693918303
VANGL1PRDM150.692412303
VANGL1CHCHD10.6915303
VANGL1INPP5E0.688378303
VANGL1CHD10.687316303
VANGL1EIF2AK40.683051403
VANGL1NOL100.67968404
VANGL1ZZZ30.676222403
VANGL1TSN0.675758605

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