| Full name: transglutaminase 4 | Alias Symbol: TGP | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 7047 | HGNC ID: HGNC:11780 | Ensembl Gene: ENSG00000163810 | OMIM ID: 600585 |
| Drug and gene relationship at DGIdb | |||
Expression of TGM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGM4 | 7047 | 217567_at | -0.1020 | 0.6168 | |
| GSE20347 | TGM4 | 7047 | 217567_at | -0.0247 | 0.7334 | |
| GSE23400 | TGM4 | 7047 | 206260_at | -0.2242 | 0.0000 | |
| GSE26886 | TGM4 | 7047 | 217567_at | 0.0671 | 0.6061 | |
| GSE29001 | TGM4 | 7047 | 206260_at | -0.1877 | 0.3927 | |
| GSE38129 | TGM4 | 7047 | 217567_at | -0.0755 | 0.1805 | |
| GSE45670 | TGM4 | 7047 | 206260_at | 0.2037 | 0.1149 | |
| GSE53622 | TGM4 | 7047 | 75045 | 0.9639 | 0.0000 | |
| GSE53624 | TGM4 | 7047 | 91630 | 0.7552 | 0.0000 | |
| GSE63941 | TGM4 | 7047 | 217567_at | 0.2898 | 0.0739 | |
| GSE77861 | TGM4 | 7047 | 217567_at | -0.1760 | 0.1488 | |
| TCGA | TGM4 | 7047 | RNAseq | 2.5304 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TGM4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGM4 | 7047 | 0 | 17 | 13 | |
| GSE20123 | TGM4 | 7047 | 0 | 18 | 12 | |
| GSE43470 | TGM4 | 7047 | 0 | 21 | 22 | |
| GSE46452 | TGM4 | 7047 | 2 | 17 | 40 | |
| GSE47630 | TGM4 | 7047 | 1 | 24 | 15 | |
| GSE54993 | TGM4 | 7047 | 7 | 2 | 61 | |
| GSE54994 | TGM4 | 7047 | 0 | 35 | 18 | |
| GSE60625 | TGM4 | 7047 | 5 | 0 | 6 | |
| GSE74703 | TGM4 | 7047 | 0 | 16 | 20 | |
| GSE74704 | TGM4 | 7047 | 0 | 13 | 7 | |
| TCGA | TGM4 | 7047 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 237; Total Number of normals: 235.
Somatic mutations of TGM4:
Generating mutation plots.
Highly correlated genes for TGM4:
Showing top 20/849 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGM4 | CST8 | 0.708068 | 6 | 0 | 6 |
| TGM4 | OOSP2 | 0.699695 | 3 | 0 | 3 |
| TGM4 | IFT122 | 0.695128 | 4 | 0 | 4 |
| TGM4 | ADM2 | 0.692531 | 7 | 0 | 7 |
| TGM4 | CEACAM21 | 0.686437 | 6 | 0 | 6 |
| TGM4 | HRH4 | 0.680772 | 3 | 0 | 3 |
| TGM4 | LMAN1L | 0.679501 | 6 | 0 | 6 |
| TGM4 | INSL5 | 0.6785 | 5 | 0 | 4 |
| TGM4 | S100A1 | 0.676458 | 6 | 0 | 5 |
| TGM4 | NPBWR2 | 0.675264 | 3 | 0 | 3 |
| TGM4 | ZMAT4 | 0.672256 | 4 | 0 | 4 |
| TGM4 | AICDA | 0.671582 | 3 | 0 | 3 |
| TGM4 | MUC8 | 0.669224 | 6 | 0 | 6 |
| TGM4 | MPO | 0.665731 | 3 | 0 | 3 |
| TGM4 | BFSP2 | 0.663248 | 4 | 0 | 4 |
| TGM4 | RGR | 0.662273 | 4 | 0 | 4 |
| TGM4 | OR10C1 | 0.662256 | 4 | 0 | 4 |
| TGM4 | GNRHR | 0.660135 | 4 | 0 | 4 |
| TGM4 | CBLN1 | 0.659002 | 5 | 0 | 3 |
| TGM4 | KCNMB2 | 0.657176 | 7 | 0 | 7 |
For details and further investigation, click here
