| Full name: transglutaminase 5 | Alias Symbol: TGX|TGMX | ||
| Type: protein-coding gene | Cytoband: 15q15.2 | ||
| Entrez ID: 9333 | HGNC ID: HGNC:11781 | Ensembl Gene: ENSG00000104055 | OMIM ID: 603805 |
| Drug and gene relationship at DGIdb | |||
Expression of TGM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGM5 | 9333 | 207911_s_at | -0.9621 | 0.1852 | |
| GSE20347 | TGM5 | 9333 | 207911_s_at | -1.0077 | 0.0000 | |
| GSE23400 | TGM5 | 9333 | 207911_s_at | -0.5838 | 0.0000 | |
| GSE26886 | TGM5 | 9333 | 207911_s_at | -1.9237 | 0.0000 | |
| GSE29001 | TGM5 | 9333 | 207911_s_at | -0.9435 | 0.0051 | |
| GSE38129 | TGM5 | 9333 | 207911_s_at | -0.8174 | 0.0000 | |
| GSE45670 | TGM5 | 9333 | 207911_s_at | -0.0280 | 0.9323 | |
| GSE53622 | TGM5 | 9333 | 106334 | -1.3157 | 0.0000 | |
| GSE53624 | TGM5 | 9333 | 106334 | -2.0965 | 0.0000 | |
| GSE63941 | TGM5 | 9333 | 207911_s_at | 0.2786 | 0.2202 | |
| GSE77861 | TGM5 | 9333 | 207911_s_at | -0.2873 | 0.1870 | |
| GSE97050 | TGM5 | 9333 | A_23_P129291 | -0.6500 | 0.2089 | |
| SRP007169 | TGM5 | 9333 | RNAseq | -6.3940 | 0.0000 | |
| SRP008496 | TGM5 | 9333 | RNAseq | -3.4121 | 0.0011 | |
| SRP064894 | TGM5 | 9333 | RNAseq | -2.3365 | 0.0000 | |
| SRP133303 | TGM5 | 9333 | RNAseq | -1.7806 | 0.0042 | |
| SRP159526 | TGM5 | 9333 | RNAseq | -2.8901 | 0.0000 | |
| SRP219564 | TGM5 | 9333 | RNAseq | -2.1810 | 0.0289 | |
| TCGA | TGM5 | 9333 | RNAseq | 0.8079 | 0.1103 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by TGM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGM5 | 9333 | 4 | 4 | 22 | |
| GSE20123 | TGM5 | 9333 | 4 | 5 | 21 | |
| GSE43470 | TGM5 | 9333 | 3 | 5 | 35 | |
| GSE46452 | TGM5 | 9333 | 3 | 7 | 49 | |
| GSE47630 | TGM5 | 9333 | 8 | 10 | 22 | |
| GSE54993 | TGM5 | 9333 | 4 | 6 | 60 | |
| GSE54994 | TGM5 | 9333 | 5 | 7 | 41 | |
| GSE60625 | TGM5 | 9333 | 4 | 0 | 7 | |
| GSE74703 | TGM5 | 9333 | 3 | 3 | 30 | |
| GSE74704 | TGM5 | 9333 | 3 | 2 | 15 | |
| TCGA | TGM5 | 9333 | 12 | 17 | 67 |
Total number of gains: 53; Total number of losses: 66; Total Number of normals: 369.
Somatic mutations of TGM5:
Generating mutation plots.
Highly correlated genes for TGM5:
Showing top 20/1085 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGM5 | RAET1E | 0.801049 | 6 | 0 | 6 |
| TGM5 | NCCRP1 | 0.788844 | 4 | 0 | 4 |
| TGM5 | VSIG10L | 0.782963 | 7 | 0 | 7 |
| TGM5 | SULT2B1 | 0.781237 | 10 | 0 | 9 |
| TGM5 | MAB21L3 | 0.780975 | 5 | 0 | 5 |
| TGM5 | RNF222 | 0.780716 | 3 | 0 | 3 |
| TGM5 | OTOP3 | 0.779699 | 3 | 0 | 3 |
| TGM5 | CNFN | 0.778324 | 8 | 0 | 8 |
| TGM5 | LYNX1 | 0.77607 | 8 | 0 | 8 |
| TGM5 | SLURP1 | 0.775291 | 12 | 0 | 11 |
| TGM5 | TGM1 | 0.764476 | 12 | 0 | 11 |
| TGM5 | TMPRSS11E | 0.764424 | 11 | 0 | 10 |
| TGM5 | PADI1 | 0.758078 | 8 | 0 | 7 |
| TGM5 | ACER1 | 0.757627 | 5 | 0 | 5 |
| TGM5 | CYSRT1 | 0.756947 | 6 | 0 | 6 |
| TGM5 | MXD1 | 0.756914 | 11 | 0 | 11 |
| TGM5 | FAM163B | 0.756191 | 3 | 0 | 3 |
| TGM5 | CEACAM5 | 0.754887 | 10 | 0 | 10 |
| TGM5 | TGM3 | 0.754814 | 13 | 0 | 12 |
| TGM5 | EPS8L2 | 0.754442 | 11 | 0 | 11 |
For details and further investigation, click here
