C7orf26

 

Full name: chromosome 7 open reading frame 26 Alias Symbol: MGC2718
Type: protein-coding gene Cytoband: 7p22.1
Entrez ID: 79034 HGNC ID: HGNC:21702 Ensembl Gene: ENSG00000146576 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of C7orf26:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C7orf26 79034 47083_at 0.1436 0.6533
GSE20347 C7orf26 79034 47083_at 0.1398 0.1556
GSE23400 C7orf26 79034 47083_at -0.0185 0.6137
GSE26886 C7orf26 79034 47083_at 0.7046 0.0001
GSE29001 C7orf26 79034 47083_at 0.0500 0.7126
GSE38129 C7orf26 79034 47083_at 0.1095 0.1257
GSE45670 C7orf26 79034 47083_at 0.0094 0.9237
GSE53622 C7orf26 79034 59503 -0.3017 0.0000
GSE53624 C7orf26 79034 59503 -0.2378 0.0000
GSE63941 C7orf26 79034 47083_at 0.0033 0.9921
GSE77861 C7orf26 79034 47083_at -0.0346 0.7928
GSE97050 C7orf26 79034 A_23_P168541 0.1771 0.4446
SRP007169 C7orf26 79034 RNAseq -0.0547 0.8896
SRP008496 C7orf26 79034 RNAseq 0.2358 0.4108
SRP064894 C7orf26 79034 RNAseq 0.5189 0.0349
SRP133303 C7orf26 79034 RNAseq 0.3033 0.0356
SRP159526 C7orf26 79034 RNAseq 0.4542 0.0163
SRP193095 C7orf26 79034 RNAseq 0.2741 0.0092
SRP219564 C7orf26 79034 RNAseq 0.2780 0.4864
TCGA C7orf26 79034 RNAseq 0.0437 0.4007

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by C7orf26 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C7orf26:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C7orf26 79034 14 1 15
GSE20123 C7orf26 79034 14 1 15
GSE43470 C7orf26 79034 7 1 35
GSE46452 C7orf26 79034 13 1 45
GSE47630 C7orf26 79034 9 1 30
GSE54993 C7orf26 79034 0 6 64
GSE54994 C7orf26 79034 20 1 32
GSE60625 C7orf26 79034 0 0 11
GSE74703 C7orf26 79034 7 0 29
GSE74704 C7orf26 79034 9 0 11
TCGA C7orf26 79034 56 4 36

Total number of gains: 149; Total number of losses: 16; Total Number of normals: 323.  


 

Somatic mutations of C7orf26:

 

Generating mutation plots.

 

Highly correlated genes for C7orf26:

 

Showing top 20/102 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C7orf26ZNF6870.837829303
C7orf26PARS20.800928303
C7orf26ZNF5260.799388303
C7orf26THAP30.772179303
C7orf26MIB20.765391303
C7orf26POC1A0.76489303
C7orf26KAT80.76403303
C7orf26IRAK10.758958303
C7orf26CHP20.756374303
C7orf26BCL2L120.749852303
C7orf26MIIP0.748484303
C7orf26MRPS20.747369303
C7orf26SDCCAG80.727188303
C7orf26GNB1L0.725524303
C7orf26PIGQ0.722512303
C7orf26FASTK0.71986303
C7orf26SAMD130.717291303
C7orf26C19orf530.715188303
C7orf26TOE10.700154403
C7orf26ZNF8910.698366303

For details and further investigation, click here