| Full name: PDGFA associated protein 1 | Alias Symbol: PAP1|PAP|HASPP28 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 11333 | HGNC ID: HGNC:14634 | Ensembl Gene: ENSG00000106244 | OMIM ID: 607075 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PDAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDAP1 | 11333 | 202290_at | -0.0210 | 0.9733 | |
| GSE20347 | PDAP1 | 11333 | 202290_at | 0.1545 | 0.4321 | |
| GSE23400 | PDAP1 | 11333 | 202290_at | 0.1880 | 0.0364 | |
| GSE26886 | PDAP1 | 11333 | 202290_at | 0.3904 | 0.0357 | |
| GSE29001 | PDAP1 | 11333 | 202290_at | 0.1508 | 0.6988 | |
| GSE38129 | PDAP1 | 11333 | 202290_at | 0.3523 | 0.1337 | |
| GSE45670 | PDAP1 | 11333 | 202290_at | 0.1471 | 0.5976 | |
| GSE53622 | PDAP1 | 11333 | 83999 | 0.4876 | 0.0000 | |
| GSE53624 | PDAP1 | 11333 | 83999 | 0.5428 | 0.0000 | |
| GSE63941 | PDAP1 | 11333 | 202290_at | 1.9834 | 0.0003 | |
| GSE77861 | PDAP1 | 11333 | 202290_at | 0.4290 | 0.0893 | |
| GSE97050 | PDAP1 | 11333 | A_23_P123256 | 0.1218 | 0.6682 | |
| SRP007169 | PDAP1 | 11333 | RNAseq | 0.8608 | 0.1031 | |
| SRP008496 | PDAP1 | 11333 | RNAseq | 0.9794 | 0.0012 | |
| SRP064894 | PDAP1 | 11333 | RNAseq | 0.2499 | 0.2185 | |
| SRP133303 | PDAP1 | 11333 | RNAseq | 0.5738 | 0.0015 | |
| SRP159526 | PDAP1 | 11333 | RNAseq | 0.1104 | 0.5778 | |
| SRP193095 | PDAP1 | 11333 | RNAseq | 0.5879 | 0.0020 | |
| SRP219564 | PDAP1 | 11333 | RNAseq | 0.2037 | 0.5645 | |
| TCGA | PDAP1 | 11333 | RNAseq | 0.2051 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PDAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDAP1 | 11333 | 13 | 0 | 17 | |
| GSE20123 | PDAP1 | 11333 | 13 | 0 | 17 | |
| GSE43470 | PDAP1 | 11333 | 6 | 1 | 36 | |
| GSE46452 | PDAP1 | 11333 | 11 | 1 | 47 | |
| GSE47630 | PDAP1 | 11333 | 8 | 3 | 29 | |
| GSE54993 | PDAP1 | 11333 | 1 | 9 | 60 | |
| GSE54994 | PDAP1 | 11333 | 16 | 3 | 34 | |
| GSE60625 | PDAP1 | 11333 | 0 | 0 | 11 | |
| GSE74703 | PDAP1 | 11333 | 6 | 1 | 29 | |
| GSE74704 | PDAP1 | 11333 | 9 | 0 | 11 | |
| TCGA | PDAP1 | 11333 | 54 | 4 | 38 |
Total number of gains: 137; Total number of losses: 22; Total Number of normals: 329.
Somatic mutations of PDAP1:
Generating mutation plots.
Highly correlated genes for PDAP1:
Showing top 20/799 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDAP1 | MRPL38 | 0.803672 | 4 | 0 | 4 |
| PDAP1 | PTCD1 | 0.792155 | 3 | 0 | 3 |
| PDAP1 | SLC38A5 | 0.766489 | 3 | 0 | 3 |
| PDAP1 | SCAF1 | 0.733786 | 3 | 0 | 3 |
| PDAP1 | FAM200A | 0.726206 | 4 | 0 | 4 |
| PDAP1 | THAP4 | 0.726122 | 4 | 0 | 4 |
| PDAP1 | EPPK1 | 0.723169 | 3 | 0 | 3 |
| PDAP1 | DHX40 | 0.715765 | 4 | 0 | 4 |
| PDAP1 | FBXO16 | 0.711259 | 3 | 0 | 3 |
| PDAP1 | FADS1 | 0.709639 | 3 | 0 | 3 |
| PDAP1 | HELB | 0.70708 | 3 | 0 | 3 |
| PDAP1 | RAB34 | 0.704381 | 3 | 0 | 3 |
| PDAP1 | RPL41 | 0.701224 | 4 | 0 | 4 |
| PDAP1 | HES4 | 0.699569 | 3 | 0 | 3 |
| PDAP1 | MTBP | 0.697816 | 4 | 0 | 4 |
| PDAP1 | ORAI1 | 0.695899 | 3 | 0 | 3 |
| PDAP1 | ZNF414 | 0.694805 | 3 | 0 | 3 |
| PDAP1 | MMS22L | 0.692352 | 3 | 0 | 3 |
| PDAP1 | NIT1 | 0.686448 | 3 | 0 | 3 |
| PDAP1 | CCDC124 | 0.684599 | 5 | 0 | 3 |
For details and further investigation, click here
