| Full name: BRCA2 and CDKN1A interacting protein | Alias Symbol: BCCIPalpha|TOK-1 | ||
| Type: protein-coding gene | Cytoband: 10q26.2 | ||
| Entrez ID: 56647 | HGNC ID: HGNC:978 | Ensembl Gene: ENSG00000107949 | OMIM ID: 611883 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BCCIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCCIP | 56647 | 227322_s_at | 0.4212 | 0.2893 | |
| GSE20347 | BCCIP | 56647 | 218264_at | 0.6025 | 0.0018 | |
| GSE23400 | BCCIP | 56647 | 218264_at | 0.4597 | 0.0000 | |
| GSE26886 | BCCIP | 56647 | 227322_s_at | 0.4506 | 0.0734 | |
| GSE29001 | BCCIP | 56647 | 218264_at | 0.6522 | 0.0592 | |
| GSE38129 | BCCIP | 56647 | 218264_at | 0.5578 | 0.0001 | |
| GSE45670 | BCCIP | 56647 | 227322_s_at | 0.2885 | 0.0481 | |
| GSE53622 | BCCIP | 56647 | 43656 | 0.2143 | 0.0015 | |
| GSE53624 | BCCIP | 56647 | 43656 | 0.4516 | 0.0000 | |
| GSE63941 | BCCIP | 56647 | 227322_s_at | 0.5322 | 0.1359 | |
| GSE77861 | BCCIP | 56647 | 227322_s_at | 0.2274 | 0.4942 | |
| GSE97050 | BCCIP | 56647 | A_24_P30206 | 0.2269 | 0.4827 | |
| SRP007169 | BCCIP | 56647 | RNAseq | 1.7675 | 0.0018 | |
| SRP008496 | BCCIP | 56647 | RNAseq | 1.3597 | 0.0001 | |
| SRP064894 | BCCIP | 56647 | RNAseq | -0.0501 | 0.6773 | |
| SRP133303 | BCCIP | 56647 | RNAseq | 0.4179 | 0.0045 | |
| SRP159526 | BCCIP | 56647 | RNAseq | 0.0470 | 0.8926 | |
| SRP193095 | BCCIP | 56647 | RNAseq | 0.1112 | 0.2915 | |
| SRP219564 | BCCIP | 56647 | RNAseq | 0.3032 | 0.2913 | |
| TCGA | BCCIP | 56647 | RNAseq | 0.0201 | 0.6847 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BCCIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCCIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCCIP | 56647 | 2 | 6 | 22 | |
| GSE20123 | BCCIP | 56647 | 2 | 6 | 22 | |
| GSE43470 | BCCIP | 56647 | 0 | 10 | 33 | |
| GSE46452 | BCCIP | 56647 | 0 | 11 | 48 | |
| GSE47630 | BCCIP | 56647 | 2 | 14 | 24 | |
| GSE54993 | BCCIP | 56647 | 8 | 1 | 61 | |
| GSE54994 | BCCIP | 56647 | 1 | 9 | 43 | |
| GSE60625 | BCCIP | 56647 | 0 | 0 | 11 | |
| GSE74703 | BCCIP | 56647 | 0 | 6 | 30 | |
| GSE74704 | BCCIP | 56647 | 2 | 2 | 16 | |
| TCGA | BCCIP | 56647 | 7 | 27 | 62 |
Total number of gains: 24; Total number of losses: 92; Total Number of normals: 372.
Somatic mutations of BCCIP:
Generating mutation plots.
Highly correlated genes for BCCIP:
Showing top 20/1326 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCCIP | CCDC15 | 0.774974 | 3 | 0 | 3 |
| BCCIP | ARL13B | 0.757953 | 3 | 0 | 3 |
| BCCIP | ROMO1 | 0.743113 | 3 | 0 | 3 |
| BCCIP | MMP15 | 0.741404 | 3 | 0 | 3 |
| BCCIP | CYBA | 0.740425 | 3 | 0 | 3 |
| BCCIP | KBTBD6 | 0.72788 | 3 | 0 | 3 |
| BCCIP | HRH1 | 0.724432 | 3 | 0 | 3 |
| BCCIP | CCNB1IP1 | 0.719651 | 6 | 0 | 6 |
| BCCIP | NUDT11 | 0.718338 | 3 | 0 | 3 |
| BCCIP | MTFMT | 0.717175 | 3 | 0 | 3 |
| BCCIP | ADAT2 | 0.715785 | 3 | 0 | 3 |
| BCCIP | DOCK7 | 0.705382 | 4 | 0 | 3 |
| BCCIP | HYLS1 | 0.70483 | 4 | 0 | 4 |
| BCCIP | LYAR | 0.704803 | 8 | 0 | 7 |
| BCCIP | MAP4K4 | 0.703397 | 3 | 0 | 3 |
| BCCIP | USP28 | 0.703161 | 3 | 0 | 3 |
| BCCIP | NIF3L1 | 0.701313 | 7 | 0 | 7 |
| BCCIP | GOLPH3 | 0.699666 | 3 | 0 | 3 |
| BCCIP | WDR75 | 0.698015 | 5 | 0 | 4 |
| BCCIP | FAM98A | 0.697343 | 4 | 0 | 3 |
For details and further investigation, click here
