| Full name: TM2 domain containing 3 | Alias Symbol: BLP2|FLJ22604 | ||
| Type: protein-coding gene | Cytoband: 15q26.3 | ||
| Entrez ID: 80213 | HGNC ID: HGNC:24128 | Ensembl Gene: ENSG00000184277 | OMIM ID: 610014 |
| Drug and gene relationship at DGIdb | |||
Expression of TM2D3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM2D3 | 80213 | 221702_s_at | 0.1635 | 0.7291 | |
| GSE20347 | TM2D3 | 80213 | 221702_s_at | 0.4657 | 0.0019 | |
| GSE23400 | TM2D3 | 80213 | 221702_s_at | 0.3612 | 0.0000 | |
| GSE26886 | TM2D3 | 80213 | 221702_s_at | 0.3615 | 0.3144 | |
| GSE29001 | TM2D3 | 80213 | 221702_s_at | 0.5613 | 0.0473 | |
| GSE38129 | TM2D3 | 80213 | 221702_s_at | 0.3703 | 0.0006 | |
| GSE45670 | TM2D3 | 80213 | 221702_s_at | 0.0867 | 0.5774 | |
| GSE53622 | TM2D3 | 80213 | 71364 | 0.1521 | 0.0289 | |
| GSE53624 | TM2D3 | 80213 | 71364 | 0.2011 | 0.0513 | |
| GSE63941 | TM2D3 | 80213 | 221702_s_at | -0.4957 | 0.2336 | |
| GSE77861 | TM2D3 | 80213 | 221702_s_at | 0.1916 | 0.3906 | |
| GSE97050 | TM2D3 | 80213 | A_24_P193498 | -0.3676 | 0.1397 | |
| SRP007169 | TM2D3 | 80213 | RNAseq | -0.2245 | 0.5481 | |
| SRP008496 | TM2D3 | 80213 | RNAseq | -0.1256 | 0.6154 | |
| SRP064894 | TM2D3 | 80213 | RNAseq | 0.2522 | 0.0711 | |
| SRP133303 | TM2D3 | 80213 | RNAseq | 0.2521 | 0.1043 | |
| SRP159526 | TM2D3 | 80213 | RNAseq | 0.4655 | 0.0136 | |
| SRP193095 | TM2D3 | 80213 | RNAseq | 0.1430 | 0.2222 | |
| SRP219564 | TM2D3 | 80213 | RNAseq | 0.2874 | 0.4176 | |
| TCGA | TM2D3 | 80213 | RNAseq | 0.0134 | 0.8046 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TM2D3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM2D3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM2D3 | 80213 | 6 | 2 | 22 | |
| GSE20123 | TM2D3 | 80213 | 6 | 2 | 22 | |
| GSE43470 | TM2D3 | 80213 | 6 | 5 | 32 | |
| GSE46452 | TM2D3 | 80213 | 3 | 7 | 49 | |
| GSE47630 | TM2D3 | 80213 | 9 | 10 | 21 | |
| GSE54993 | TM2D3 | 80213 | 4 | 7 | 59 | |
| GSE54994 | TM2D3 | 80213 | 8 | 7 | 38 | |
| GSE60625 | TM2D3 | 80213 | 4 | 0 | 7 | |
| GSE74703 | TM2D3 | 80213 | 5 | 4 | 27 | |
| GSE74704 | TM2D3 | 80213 | 3 | 3 | 14 | |
| TCGA | TM2D3 | 80213 | 19 | 10 | 67 |
Total number of gains: 73; Total number of losses: 57; Total Number of normals: 358.
Somatic mutations of TM2D3:
Generating mutation plots.
Highly correlated genes for TM2D3:
Showing top 20/932 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM2D3 | HYLS1 | 0.812865 | 3 | 0 | 3 |
| TM2D3 | MRPL32 | 0.752302 | 3 | 0 | 3 |
| TM2D3 | FAM76B | 0.751854 | 3 | 0 | 3 |
| TM2D3 | CHM | 0.747762 | 3 | 0 | 3 |
| TM2D3 | CREBL2 | 0.736923 | 4 | 0 | 4 |
| TM2D3 | CYTH3 | 0.736048 | 3 | 0 | 3 |
| TM2D3 | GNA11 | 0.735717 | 3 | 0 | 3 |
| TM2D3 | CREB5 | 0.734981 | 3 | 0 | 3 |
| TM2D3 | FARS2 | 0.730133 | 3 | 0 | 3 |
| TM2D3 | FAM118B | 0.728945 | 3 | 0 | 3 |
| TM2D3 | ARL13B | 0.722674 | 3 | 0 | 3 |
| TM2D3 | TMEM17 | 0.720473 | 3 | 0 | 3 |
| TM2D3 | TATDN1 | 0.713466 | 4 | 0 | 4 |
| TM2D3 | ZNF641 | 0.712783 | 4 | 0 | 4 |
| TM2D3 | SNAPIN | 0.706959 | 3 | 0 | 3 |
| TM2D3 | COG2 | 0.701694 | 6 | 0 | 5 |
| TM2D3 | ORAI1 | 0.700868 | 3 | 0 | 3 |
| TM2D3 | C16orf87 | 0.700488 | 3 | 0 | 3 |
| TM2D3 | KLHL15 | 0.698295 | 4 | 0 | 3 |
| TM2D3 | OSBPL6 | 0.697917 | 3 | 0 | 3 |
For details and further investigation, click here
