| Full name: SFT2 domain containing 1 | Alias Symbol: MGC19825|pRGR1 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 113402 | HGNC ID: HGNC:21102 | Ensembl Gene: ENSG00000198818 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SFT2D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFT2D1 | 113402 | 225849_s_at | 0.3356 | 0.3522 | |
| GSE26886 | SFT2D1 | 113402 | 225849_s_at | -0.3618 | 0.0127 | |
| GSE45670 | SFT2D1 | 113402 | 225849_s_at | 0.5805 | 0.0001 | |
| GSE53622 | SFT2D1 | 113402 | 76801 | 0.2674 | 0.0000 | |
| GSE53624 | SFT2D1 | 113402 | 76801 | 0.2467 | 0.0021 | |
| GSE63941 | SFT2D1 | 113402 | 225849_s_at | 0.1414 | 0.6819 | |
| GSE77861 | SFT2D1 | 113402 | 225849_s_at | 0.2562 | 0.2562 | |
| GSE97050 | SFT2D1 | 113402 | A_23_P321959 | 0.4451 | 0.2479 | |
| SRP007169 | SFT2D1 | 113402 | RNAseq | 0.4605 | 0.2119 | |
| SRP008496 | SFT2D1 | 113402 | RNAseq | 0.3336 | 0.1772 | |
| SRP064894 | SFT2D1 | 113402 | RNAseq | 0.3405 | 0.0208 | |
| SRP133303 | SFT2D1 | 113402 | RNAseq | 0.3849 | 0.0055 | |
| SRP159526 | SFT2D1 | 113402 | RNAseq | 0.1126 | 0.6600 | |
| SRP193095 | SFT2D1 | 113402 | RNAseq | -0.1565 | 0.2391 | |
| SRP219564 | SFT2D1 | 113402 | RNAseq | 0.1256 | 0.6596 | |
| TCGA | SFT2D1 | 113402 | RNAseq | -0.0047 | 0.9391 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SFT2D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFT2D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFT2D1 | 113402 | 2 | 6 | 22 | |
| GSE20123 | SFT2D1 | 113402 | 2 | 6 | 22 | |
| GSE43470 | SFT2D1 | 113402 | 3 | 0 | 40 | |
| GSE46452 | SFT2D1 | 113402 | 3 | 10 | 46 | |
| GSE47630 | SFT2D1 | 113402 | 7 | 7 | 26 | |
| GSE54993 | SFT2D1 | 113402 | 4 | 3 | 63 | |
| GSE54994 | SFT2D1 | 113402 | 9 | 8 | 36 | |
| GSE60625 | SFT2D1 | 113402 | 1 | 1 | 9 | |
| GSE74703 | SFT2D1 | 113402 | 3 | 0 | 33 | |
| GSE74704 | SFT2D1 | 113402 | 1 | 3 | 16 | |
| TCGA | SFT2D1 | 113402 | 13 | 21 | 62 |
Total number of gains: 48; Total number of losses: 65; Total Number of normals: 375.
Somatic mutations of SFT2D1:
Generating mutation plots.
Highly correlated genes for SFT2D1:
Showing top 20/233 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFT2D1 | PSMB5 | 0.709419 | 5 | 0 | 5 |
| SFT2D1 | CYB561D2 | 0.705064 | 3 | 0 | 3 |
| SFT2D1 | ERN1 | 0.695366 | 3 | 0 | 3 |
| SFT2D1 | FEN1 | 0.693848 | 4 | 0 | 3 |
| SFT2D1 | CHEK2 | 0.691387 | 3 | 0 | 3 |
| SFT2D1 | FBXO22 | 0.680485 | 5 | 0 | 4 |
| SFT2D1 | MYO10 | 0.666889 | 4 | 0 | 4 |
| SFT2D1 | G3BP1 | 0.657624 | 4 | 0 | 3 |
| SFT2D1 | CD3G | 0.653457 | 3 | 0 | 3 |
| SFT2D1 | REXO4 | 0.647794 | 4 | 0 | 3 |
| SFT2D1 | VMA21 | 0.644214 | 3 | 0 | 3 |
| SFT2D1 | FANCG | 0.643183 | 4 | 0 | 3 |
| SFT2D1 | MFSD3 | 0.635307 | 3 | 0 | 3 |
| SFT2D1 | CDC20 | 0.634785 | 5 | 0 | 3 |
| SFT2D1 | DHX9 | 0.63034 | 5 | 0 | 5 |
| SFT2D1 | C4orf46 | 0.626663 | 4 | 0 | 3 |
| SFT2D1 | GART | 0.626414 | 4 | 0 | 3 |
| SFT2D1 | CSTF3 | 0.625087 | 3 | 0 | 3 |
| SFT2D1 | SDC1 | 0.622643 | 3 | 0 | 3 |
| SFT2D1 | TMEM182 | 0.622221 | 5 | 0 | 4 |
For details and further investigation, click here
