| Full name: tumor protein p53 inducible nuclear protein 1 | Alias Symbol: DKFZp434M1317|FLJ22139|P53DINP1|SIP|TP53INP1A|TP53INP1B|Teap | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 94241 | HGNC ID: HGNC:18022 | Ensembl Gene: ENSG00000164938 | OMIM ID: 606185 |
| Drug and gene relationship at DGIdb | |||
Expression of TP53INP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TP53INP1 | 94241 | 225912_at | 0.1829 | 0.8452 | |
| GSE26886 | TP53INP1 | 94241 | 225912_at | -0.9722 | 0.0033 | |
| GSE45670 | TP53INP1 | 94241 | 225912_at | -0.2982 | 0.1280 | |
| GSE53622 | TP53INP1 | 94241 | 31970 | -0.0779 | 0.4229 | |
| GSE53624 | TP53INP1 | 94241 | 4554 | -0.3329 | 0.0000 | |
| GSE63941 | TP53INP1 | 94241 | 225912_at | -2.7755 | 0.0060 | |
| GSE77861 | TP53INP1 | 94241 | 225912_at | -0.1181 | 0.6632 | |
| GSE97050 | TP53INP1 | 94241 | A_23_P168882 | 0.1124 | 0.5442 | |
| SRP007169 | TP53INP1 | 94241 | RNAseq | -0.4590 | 0.1818 | |
| SRP008496 | TP53INP1 | 94241 | RNAseq | -0.0713 | 0.8037 | |
| SRP064894 | TP53INP1 | 94241 | RNAseq | 0.1092 | 0.6433 | |
| SRP133303 | TP53INP1 | 94241 | RNAseq | 0.1814 | 0.4987 | |
| SRP159526 | TP53INP1 | 94241 | RNAseq | 0.1663 | 0.7556 | |
| SRP193095 | TP53INP1 | 94241 | RNAseq | -0.1699 | 0.3615 | |
| SRP219564 | TP53INP1 | 94241 | RNAseq | 0.0328 | 0.9245 | |
| TCGA | TP53INP1 | 94241 | RNAseq | -0.3319 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TP53INP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TP53INP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TP53INP1 | 94241 | 16 | 0 | 14 | |
| GSE20123 | TP53INP1 | 94241 | 17 | 0 | 13 | |
| GSE43470 | TP53INP1 | 94241 | 21 | 1 | 21 | |
| GSE46452 | TP53INP1 | 94241 | 23 | 0 | 36 | |
| GSE47630 | TP53INP1 | 94241 | 24 | 0 | 16 | |
| GSE54993 | TP53INP1 | 94241 | 0 | 20 | 50 | |
| GSE54994 | TP53INP1 | 94241 | 34 | 1 | 18 | |
| GSE60625 | TP53INP1 | 94241 | 0 | 4 | 7 | |
| GSE74703 | TP53INP1 | 94241 | 18 | 1 | 17 | |
| GSE74704 | TP53INP1 | 94241 | 12 | 0 | 8 | |
| TCGA | TP53INP1 | 94241 | 56 | 1 | 39 |
Total number of gains: 221; Total number of losses: 28; Total Number of normals: 239.
Somatic mutations of TP53INP1:
Generating mutation plots.
Highly correlated genes for TP53INP1:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TP53INP1 | RIT1 | 0.76092 | 3 | 0 | 3 |
| TP53INP1 | IL22RA2 | 0.748242 | 3 | 0 | 3 |
| TP53INP1 | LIMD1 | 0.697801 | 3 | 0 | 3 |
| TP53INP1 | PRKCB | 0.672897 | 4 | 0 | 3 |
| TP53INP1 | ZNF682 | 0.668592 | 4 | 0 | 4 |
| TP53INP1 | NISCH | 0.655838 | 4 | 0 | 4 |
| TP53INP1 | ZNF831 | 0.649113 | 4 | 0 | 3 |
| TP53INP1 | TJP2 | 0.64777 | 3 | 0 | 3 |
| TP53INP1 | RBM43 | 0.632748 | 5 | 0 | 4 |
| TP53INP1 | MYCL | 0.628102 | 3 | 0 | 3 |
| TP53INP1 | TMCO3 | 0.625816 | 4 | 0 | 3 |
| TP53INP1 | TNFRSF14 | 0.622664 | 4 | 0 | 3 |
| TP53INP1 | ZNF763 | 0.622267 | 5 | 0 | 3 |
| TP53INP1 | SLC26A2 | 0.618362 | 4 | 0 | 3 |
| TP53INP1 | SETDB2 | 0.613795 | 4 | 0 | 3 |
| TP53INP1 | CD72 | 0.601592 | 4 | 0 | 3 |
| TP53INP1 | CYTIP | 0.59429 | 4 | 0 | 3 |
| TP53INP1 | IKBKB | 0.593142 | 5 | 0 | 4 |
| TP53INP1 | SHC3 | 0.592381 | 4 | 0 | 3 |
| TP53INP1 | ZC3H6 | 0.591885 | 4 | 0 | 3 |
For details and further investigation, click here
