| Full name: intraflagellar transport 27 | Alias Symbol: RAYL|BBS19 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 11020 | HGNC ID: HGNC:18626 | Ensembl Gene: ENSG00000100360 | OMIM ID: 615870 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT27 | 11020 | 205037_at | 0.5615 | 0.2556 | |
| GSE20347 | IFT27 | 11020 | 205037_at | 0.5187 | 0.0067 | |
| GSE23400 | IFT27 | 11020 | 213784_at | -0.1890 | 0.0000 | |
| GSE26886 | IFT27 | 11020 | 205037_at | 0.5866 | 0.0768 | |
| GSE29001 | IFT27 | 11020 | 213784_at | -0.1776 | 0.2635 | |
| GSE38129 | IFT27 | 11020 | 205037_at | 0.5170 | 0.0193 | |
| GSE45670 | IFT27 | 11020 | 205037_at | 0.3755 | 0.1204 | |
| GSE53622 | IFT27 | 11020 | 70399 | 0.3003 | 0.0000 | |
| GSE53624 | IFT27 | 11020 | 70399 | 0.2045 | 0.0001 | |
| GSE63941 | IFT27 | 11020 | 205037_at | 0.5552 | 0.5075 | |
| GSE77861 | IFT27 | 11020 | 205037_at | 0.2550 | 0.3649 | |
| GSE97050 | IFT27 | 11020 | A_33_P3399560 | -0.0825 | 0.7429 | |
| SRP007169 | IFT27 | 11020 | RNAseq | 0.7647 | 0.0869 | |
| SRP008496 | IFT27 | 11020 | RNAseq | 0.8225 | 0.0075 | |
| SRP064894 | IFT27 | 11020 | RNAseq | 0.7933 | 0.0528 | |
| SRP133303 | IFT27 | 11020 | RNAseq | 0.3948 | 0.0259 | |
| SRP159526 | IFT27 | 11020 | RNAseq | 1.2656 | 0.0000 | |
| SRP193095 | IFT27 | 11020 | RNAseq | 0.3409 | 0.0547 | |
| SRP219564 | IFT27 | 11020 | RNAseq | 0.0827 | 0.8759 | |
| TCGA | IFT27 | 11020 | RNAseq | -0.1320 | 0.1847 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IFT27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT27 | 11020 | 6 | 6 | 18 | |
| GSE20123 | IFT27 | 11020 | 6 | 5 | 19 | |
| GSE43470 | IFT27 | 11020 | 4 | 6 | 33 | |
| GSE46452 | IFT27 | 11020 | 31 | 1 | 27 | |
| GSE47630 | IFT27 | 11020 | 8 | 5 | 27 | |
| GSE54993 | IFT27 | 11020 | 3 | 6 | 61 | |
| GSE54994 | IFT27 | 11020 | 10 | 9 | 34 | |
| GSE60625 | IFT27 | 11020 | 5 | 0 | 6 | |
| GSE74703 | IFT27 | 11020 | 4 | 4 | 28 | |
| GSE74704 | IFT27 | 11020 | 3 | 2 | 15 | |
| TCGA | IFT27 | 11020 | 27 | 16 | 53 |
Total number of gains: 107; Total number of losses: 60; Total Number of normals: 321.
Somatic mutations of IFT27:
Generating mutation plots.
Highly correlated genes for IFT27:
Showing top 20/151 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT27 | ZFPM1 | 0.747253 | 4 | 0 | 4 |
| IFT27 | CCL26 | 0.701307 | 4 | 0 | 4 |
| IFT27 | AGPAT1 | 0.691616 | 4 | 0 | 3 |
| IFT27 | DACH1 | 0.686465 | 3 | 0 | 3 |
| IFT27 | P4HA3 | 0.685975 | 3 | 0 | 3 |
| IFT27 | RASL10A | 0.681475 | 4 | 0 | 3 |
| IFT27 | GP9 | 0.680213 | 3 | 0 | 3 |
| IFT27 | ZBTB24 | 0.677534 | 3 | 0 | 3 |
| IFT27 | SIMC1 | 0.668765 | 3 | 0 | 3 |
| IFT27 | RIMS3 | 0.665745 | 4 | 0 | 4 |
| IFT27 | ZNF821 | 0.651756 | 4 | 0 | 3 |
| IFT27 | ALDH16A1 | 0.645761 | 3 | 0 | 3 |
| IFT27 | SDHAF1 | 0.644451 | 4 | 0 | 3 |
| IFT27 | DNM1 | 0.643204 | 4 | 0 | 3 |
| IFT27 | OSGIN1 | 0.641442 | 4 | 0 | 3 |
| IFT27 | PKDCC | 0.632385 | 4 | 0 | 3 |
| IFT27 | PEF1 | 0.630274 | 5 | 0 | 4 |
| IFT27 | ASTN2 | 0.623094 | 5 | 0 | 3 |
| IFT27 | SDCCAG8 | 0.620428 | 3 | 0 | 3 |
| IFT27 | TMCO3 | 0.620232 | 6 | 0 | 4 |
For details and further investigation, click here
