| Full name: transmembrane protein with EGF like and two follistatin like domains 2 | Alias Symbol: TENB2|HPP1|TR|TPEF|CT120.2 | ||
| Type: protein-coding gene | Cytoband: 2q32.3 | ||
| Entrez ID: 23671 | HGNC ID: HGNC:11867 | Ensembl Gene: ENSG00000144339 | OMIM ID: 605734 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEFF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEFF2 | 23671 | 224321_at | 0.8477 | 0.2669 | |
| GSE26886 | TMEFF2 | 23671 | 224321_at | -0.5348 | 0.1010 | |
| GSE45670 | TMEFF2 | 23671 | 224321_at | -0.1061 | 0.7477 | |
| GSE53622 | TMEFF2 | 23671 | 155456 | -2.8247 | 0.0000 | |
| GSE53624 | TMEFF2 | 23671 | 155456 | -2.7872 | 0.0000 | |
| GSE63941 | TMEFF2 | 23671 | 224321_at | -0.8769 | 0.1504 | |
| GSE77861 | TMEFF2 | 23671 | 224321_at | -0.1299 | 0.3803 | |
| SRP133303 | TMEFF2 | 23671 | RNAseq | -2.1095 | 0.0011 | |
| TCGA | TMEFF2 | 23671 | RNAseq | -3.4272 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMEFF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEFF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEFF2 | 23671 | 9 | 3 | 18 | |
| GSE20123 | TMEFF2 | 23671 | 9 | 3 | 18 | |
| GSE43470 | TMEFF2 | 23671 | 3 | 1 | 39 | |
| GSE46452 | TMEFF2 | 23671 | 1 | 4 | 54 | |
| GSE47630 | TMEFF2 | 23671 | 4 | 5 | 31 | |
| GSE54993 | TMEFF2 | 23671 | 0 | 5 | 65 | |
| GSE54994 | TMEFF2 | 23671 | 12 | 6 | 35 | |
| GSE60625 | TMEFF2 | 23671 | 0 | 3 | 8 | |
| GSE74703 | TMEFF2 | 23671 | 2 | 1 | 33 | |
| GSE74704 | TMEFF2 | 23671 | 4 | 2 | 14 | |
| TCGA | TMEFF2 | 23671 | 25 | 7 | 64 |
Total number of gains: 69; Total number of losses: 40; Total Number of normals: 379.
Somatic mutations of TMEFF2:
Generating mutation plots.
Highly correlated genes for TMEFF2:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEFF2 | TNXB | 0.724518 | 3 | 0 | 3 |
| TMEFF2 | FAIM2 | 0.687757 | 3 | 0 | 3 |
| TMEFF2 | YTHDF2 | 0.666535 | 3 | 0 | 3 |
| TMEFF2 | SVIP | 0.625921 | 3 | 0 | 3 |
| TMEFF2 | NFATC4 | 0.615866 | 3 | 0 | 3 |
| TMEFF2 | IL34 | 0.608894 | 3 | 0 | 3 |
| TMEFF2 | ZNF366 | 0.607977 | 3 | 0 | 3 |
| TMEFF2 | TCAIM | 0.606219 | 4 | 0 | 3 |
| TMEFF2 | FDFT1 | 0.604501 | 3 | 0 | 3 |
| TMEFF2 | RCHY1 | 0.603447 | 4 | 0 | 3 |
| TMEFF2 | TIGD2 | 0.603018 | 3 | 0 | 3 |
| TMEFF2 | TMA7 | 0.601169 | 3 | 0 | 3 |
| TMEFF2 | SHMT1 | 0.594323 | 3 | 0 | 3 |
| TMEFF2 | RMST | 0.590249 | 4 | 0 | 3 |
| TMEFF2 | ZNF135 | 0.575456 | 5 | 0 | 4 |
| TMEFF2 | PHF10 | 0.571819 | 4 | 0 | 3 |
| TMEFF2 | SLC16A7 | 0.56688 | 4 | 0 | 3 |
| TMEFF2 | CMPK1 | 0.564874 | 4 | 0 | 4 |
| TMEFF2 | OXER1 | 0.56415 | 3 | 0 | 3 |
| TMEFF2 | TMEM80 | 0.560695 | 4 | 0 | 3 |
For details and further investigation, click here
