| Full name: transmembrane protein 80 | Alias Symbol: FLJ38216 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 283232 | HGNC ID: HGNC:27453 | Ensembl Gene: ENSG00000177042 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM80 | 283232 | 65630_at | -0.6497 | 0.2171 | |
| GSE20347 | TMEM80 | 283232 | 221951_at | -0.9836 | 0.0000 | |
| GSE23400 | TMEM80 | 283232 | 221951_at | -0.6033 | 0.0000 | |
| GSE26886 | TMEM80 | 283232 | 1559132_at | -2.3650 | 0.0000 | |
| GSE29001 | TMEM80 | 283232 | 221951_at | -0.9074 | 0.0000 | |
| GSE38129 | TMEM80 | 283232 | 65630_at | -0.9723 | 0.0000 | |
| GSE45670 | TMEM80 | 283232 | 221951_at | -0.6360 | 0.0028 | |
| GSE53622 | TMEM80 | 283232 | 33523 | -1.4948 | 0.0000 | |
| GSE53624 | TMEM80 | 283232 | 33523 | -1.5604 | 0.0000 | |
| GSE63941 | TMEM80 | 283232 | 65630_at | -0.2849 | 0.6071 | |
| GSE77861 | TMEM80 | 283232 | 221951_at | -0.7071 | 0.0389 | |
| GSE97050 | TMEM80 | 283232 | A_23_P332960 | -0.6937 | 0.0891 | |
| SRP007169 | TMEM80 | 283232 | RNAseq | -3.1137 | 0.0000 | |
| SRP008496 | TMEM80 | 283232 | RNAseq | -2.7135 | 0.0000 | |
| SRP064894 | TMEM80 | 283232 | RNAseq | -1.5160 | 0.0000 | |
| SRP133303 | TMEM80 | 283232 | RNAseq | -1.3352 | 0.0000 | |
| SRP159526 | TMEM80 | 283232 | RNAseq | -1.4981 | 0.0000 | |
| SRP193095 | TMEM80 | 283232 | RNAseq | -1.4151 | 0.0000 | |
| SRP219564 | TMEM80 | 283232 | RNAseq | -1.1629 | 0.0140 | |
| TCGA | TMEM80 | 283232 | RNAseq | -0.2979 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by TMEM80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM80 | 283232 | 1 | 11 | 18 | |
| GSE20123 | TMEM80 | 283232 | 1 | 12 | 17 | |
| GSE43470 | TMEM80 | 283232 | 1 | 10 | 32 | |
| GSE46452 | TMEM80 | 283232 | 7 | 8 | 44 | |
| GSE47630 | TMEM80 | 283232 | 4 | 12 | 24 | |
| GSE54993 | TMEM80 | 283232 | 3 | 1 | 66 | |
| GSE54994 | TMEM80 | 283232 | 1 | 12 | 40 | |
| GSE60625 | TMEM80 | 283232 | 0 | 0 | 11 | |
| GSE74703 | TMEM80 | 283232 | 1 | 8 | 27 | |
| GSE74704 | TMEM80 | 283232 | 0 | 8 | 12 | |
| TCGA | TMEM80 | 283232 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of TMEM80:
Generating mutation plots.
Highly correlated genes for TMEM80:
Showing top 20/1708 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM80 | MTHFR | 0.795572 | 3 | 0 | 3 |
| TMEM80 | SH3BGRL2 | 0.787438 | 7 | 0 | 7 |
| TMEM80 | SLC10A5 | 0.786662 | 3 | 0 | 3 |
| TMEM80 | CGNL1 | 0.785019 | 7 | 0 | 7 |
| TMEM80 | HPGD | 0.7825 | 11 | 0 | 11 |
| TMEM80 | CASC3 | 0.77988 | 3 | 0 | 3 |
| TMEM80 | SCNN1B | 0.779403 | 10 | 0 | 10 |
| TMEM80 | RMND5B | 0.779303 | 11 | 0 | 11 |
| TMEM80 | SMIM5 | 0.777745 | 6 | 0 | 6 |
| TMEM80 | CA13 | 0.777529 | 3 | 0 | 3 |
| TMEM80 | CPEB3 | 0.770956 | 10 | 0 | 10 |
| TMEM80 | PAQR8 | 0.767935 | 7 | 0 | 7 |
| TMEM80 | MGLL | 0.766096 | 11 | 0 | 10 |
| TMEM80 | VSIG10L | 0.761429 | 5 | 0 | 5 |
| TMEM80 | SASH1 | 0.761317 | 11 | 0 | 11 |
| TMEM80 | C18orf25 | 0.761104 | 11 | 0 | 11 |
| TMEM80 | WDR26 | 0.75678 | 10 | 0 | 10 |
| TMEM80 | SORT1 | 0.756745 | 11 | 0 | 11 |
| TMEM80 | GYS2 | 0.753193 | 10 | 0 | 10 |
| TMEM80 | EPS8L1 | 0.75143 | 10 | 0 | 10 |
For details and further investigation, click here
