| Full name: platelet activating factor acetylhydrolase 2 | Alias Symbol: HSD-PLA2 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 5051 | HGNC ID: HGNC:8579 | Ensembl Gene: ENSG00000158006 | OMIM ID: 602344 |
| Drug and gene relationship at DGIdb | |||
Expression of PAFAH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAFAH2 | 5051 | 205232_s_at | -0.1707 | 0.6143 | |
| GSE20347 | PAFAH2 | 5051 | 205233_s_at | -0.4943 | 0.0001 | |
| GSE23400 | PAFAH2 | 5051 | 205232_s_at | -0.0618 | 0.1236 | |
| GSE26886 | PAFAH2 | 5051 | 205232_s_at | -0.8935 | 0.0000 | |
| GSE29001 | PAFAH2 | 5051 | 205233_s_at | -0.3815 | 0.1048 | |
| GSE38129 | PAFAH2 | 5051 | 205233_s_at | -0.4763 | 0.0003 | |
| GSE45670 | PAFAH2 | 5051 | 205233_s_at | 0.0006 | 0.9974 | |
| GSE53622 | PAFAH2 | 5051 | 91390 | 0.4163 | 0.0470 | |
| GSE53624 | PAFAH2 | 5051 | 87258 | -0.6851 | 0.0000 | |
| GSE63941 | PAFAH2 | 5051 | 205232_s_at | 1.0379 | 0.0028 | |
| GSE77861 | PAFAH2 | 5051 | 205232_s_at | -0.1045 | 0.5137 | |
| GSE97050 | PAFAH2 | 5051 | A_24_P71153 | -0.0069 | 0.9774 | |
| SRP007169 | PAFAH2 | 5051 | RNAseq | -0.9531 | 0.0385 | |
| SRP008496 | PAFAH2 | 5051 | RNAseq | -1.1392 | 0.0000 | |
| SRP064894 | PAFAH2 | 5051 | RNAseq | -0.3863 | 0.0049 | |
| SRP133303 | PAFAH2 | 5051 | RNAseq | -0.2400 | 0.2822 | |
| SRP159526 | PAFAH2 | 5051 | RNAseq | -0.7161 | 0.0004 | |
| SRP193095 | PAFAH2 | 5051 | RNAseq | -0.8698 | 0.0000 | |
| SRP219564 | PAFAH2 | 5051 | RNAseq | -0.7296 | 0.0032 | |
| TCGA | PAFAH2 | 5051 | RNAseq | -0.4921 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PAFAH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAFAH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAFAH2 | 5051 | 0 | 6 | 24 | |
| GSE20123 | PAFAH2 | 5051 | 0 | 5 | 25 | |
| GSE43470 | PAFAH2 | 5051 | 2 | 6 | 35 | |
| GSE46452 | PAFAH2 | 5051 | 5 | 1 | 53 | |
| GSE47630 | PAFAH2 | 5051 | 8 | 3 | 29 | |
| GSE54993 | PAFAH2 | 5051 | 2 | 1 | 67 | |
| GSE54994 | PAFAH2 | 5051 | 10 | 4 | 39 | |
| GSE60625 | PAFAH2 | 5051 | 0 | 0 | 11 | |
| GSE74703 | PAFAH2 | 5051 | 1 | 4 | 31 | |
| GSE74704 | PAFAH2 | 5051 | 0 | 0 | 20 | |
| TCGA | PAFAH2 | 5051 | 9 | 25 | 62 |
Total number of gains: 37; Total number of losses: 55; Total Number of normals: 396.
Somatic mutations of PAFAH2:
Generating mutation plots.
Highly correlated genes for PAFAH2:
Showing top 20/441 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAFAH2 | UQCRC1 | 0.808896 | 3 | 0 | 3 |
| PAFAH2 | TMEM125 | 0.729924 | 5 | 0 | 5 |
| PAFAH2 | RGS12 | 0.701249 | 5 | 0 | 4 |
| PAFAH2 | PRAMEF12 | 0.697686 | 3 | 0 | 3 |
| PAFAH2 | RAB27B | 0.696072 | 7 | 0 | 7 |
| PAFAH2 | DGAT2 | 0.694957 | 4 | 0 | 4 |
| PAFAH2 | S100A16 | 0.690742 | 4 | 0 | 4 |
| PAFAH2 | ZBTB7C | 0.677971 | 4 | 0 | 3 |
| PAFAH2 | KCTD5 | 0.675824 | 4 | 0 | 3 |
| PAFAH2 | EHF | 0.67075 | 7 | 0 | 7 |
| PAFAH2 | OR2H2 | 0.666502 | 4 | 0 | 4 |
| PAFAH2 | OR12D3 | 0.664075 | 3 | 0 | 3 |
| PAFAH2 | RIPK4 | 0.663946 | 8 | 0 | 7 |
| PAFAH2 | EPHA1 | 0.662535 | 9 | 0 | 9 |
| PAFAH2 | PTK6 | 0.6617 | 9 | 0 | 8 |
| PAFAH2 | NEBL | 0.661031 | 9 | 0 | 9 |
| PAFAH2 | ARHGAP32 | 0.660474 | 6 | 0 | 5 |
| PAFAH2 | NLRP13 | 0.659961 | 3 | 0 | 3 |
| PAFAH2 | NMRK1 | 0.658098 | 5 | 0 | 5 |
| PAFAH2 | RAET1E | 0.657666 | 5 | 0 | 4 |
For details and further investigation, click here
