| Full name: cell division cycle 123 | Alias Symbol: D123 | ||
| Type: protein-coding gene | Cytoband: 10p14-p13 | ||
| Entrez ID: 8872 | HGNC ID: HGNC:16827 | Ensembl Gene: ENSG00000151465 | OMIM ID: 617708 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC123:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC123 | 8872 | 201725_at | 0.2156 | 0.6105 | |
| GSE20347 | CDC123 | 8872 | 201725_at | 0.2808 | 0.0753 | |
| GSE23400 | CDC123 | 8872 | 201725_at | 0.2965 | 0.0000 | |
| GSE26886 | CDC123 | 8872 | 201725_at | -0.5120 | 0.0347 | |
| GSE29001 | CDC123 | 8872 | 201725_at | 0.0613 | 0.9246 | |
| GSE38129 | CDC123 | 8872 | 201725_at | 0.4021 | 0.0019 | |
| GSE45670 | CDC123 | 8872 | 201725_at | 0.1500 | 0.3579 | |
| GSE53622 | CDC123 | 8872 | 98706 | 0.1359 | 0.0343 | |
| GSE53624 | CDC123 | 8872 | 98706 | 0.2274 | 0.0062 | |
| GSE63941 | CDC123 | 8872 | 201725_at | 0.7523 | 0.0647 | |
| GSE77861 | CDC123 | 8872 | 201725_at | -0.0443 | 0.9012 | |
| GSE97050 | CDC123 | 8872 | A_24_P303974 | 0.4722 | 0.1552 | |
| SRP007169 | CDC123 | 8872 | RNAseq | -0.2221 | 0.6079 | |
| SRP008496 | CDC123 | 8872 | RNAseq | -0.2607 | 0.2705 | |
| SRP064894 | CDC123 | 8872 | RNAseq | 0.0978 | 0.5385 | |
| SRP133303 | CDC123 | 8872 | RNAseq | 0.0663 | 0.6366 | |
| SRP159526 | CDC123 | 8872 | RNAseq | -0.1181 | 0.7463 | |
| SRP193095 | CDC123 | 8872 | RNAseq | -0.0960 | 0.4095 | |
| SRP219564 | CDC123 | 8872 | RNAseq | -0.1759 | 0.5905 | |
| TCGA | CDC123 | 8872 | RNAseq | 0.2546 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDC123 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC123:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC123 | 8872 | 6 | 7 | 17 | |
| GSE20123 | CDC123 | 8872 | 6 | 6 | 18 | |
| GSE43470 | CDC123 | 8872 | 3 | 5 | 35 | |
| GSE46452 | CDC123 | 8872 | 2 | 14 | 43 | |
| GSE47630 | CDC123 | 8872 | 6 | 14 | 20 | |
| GSE54993 | CDC123 | 8872 | 11 | 1 | 58 | |
| GSE54994 | CDC123 | 8872 | 4 | 9 | 40 | |
| GSE60625 | CDC123 | 8872 | 0 | 0 | 11 | |
| GSE74703 | CDC123 | 8872 | 2 | 3 | 31 | |
| GSE74704 | CDC123 | 8872 | 1 | 5 | 14 | |
| TCGA | CDC123 | 8872 | 20 | 24 | 52 |
Total number of gains: 61; Total number of losses: 88; Total Number of normals: 339.
Somatic mutations of CDC123:
Generating mutation plots.
Highly correlated genes for CDC123:
Showing top 20/820 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC123 | NUDT5 | 0.823908 | 8 | 0 | 8 |
| CDC123 | WDR36 | 0.81271 | 3 | 0 | 3 |
| CDC123 | NUP50 | 0.801274 | 3 | 0 | 3 |
| CDC123 | NDUFA13 | 0.767398 | 3 | 0 | 3 |
| CDC123 | REST | 0.766883 | 3 | 0 | 3 |
| CDC123 | INTS12 | 0.766339 | 4 | 0 | 4 |
| CDC123 | IRAK2 | 0.759601 | 3 | 0 | 3 |
| CDC123 | POLB | 0.748851 | 4 | 0 | 3 |
| CDC123 | TYW3 | 0.738399 | 3 | 0 | 3 |
| CDC123 | PRELID1 | 0.738205 | 4 | 0 | 4 |
| CDC123 | NDUFA10 | 0.734862 | 4 | 0 | 4 |
| CDC123 | TMEM218 | 0.73303 | 3 | 0 | 3 |
| CDC123 | SAMM50 | 0.732231 | 6 | 0 | 6 |
| CDC123 | TMEM126B | 0.728863 | 4 | 0 | 4 |
| CDC123 | CSNK2A2 | 0.724499 | 4 | 0 | 3 |
| CDC123 | ALAS1 | 0.720449 | 4 | 0 | 4 |
| CDC123 | ADAT1 | 0.719191 | 4 | 0 | 3 |
| CDC123 | TNFAIP8 | 0.718933 | 3 | 0 | 3 |
| CDC123 | FRMD6 | 0.718113 | 3 | 0 | 3 |
| CDC123 | FARS2 | 0.717248 | 3 | 0 | 3 |
For details and further investigation, click here
