PSKH1

 

Full name: protein serine kinase H1 Alias Symbol: 
Type: protein-coding gene Cytoband: 16q22.1
Entrez ID: 5681 HGNC ID: HGNC:9529 Ensembl Gene: ENSG00000159792 OMIM ID: 177015
Drug and gene relationship at DGIdb

 

Expression of PSKH1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSKH1 5681 213141_at 0.3527 0.3066
GSE20347 PSKH1 5681 213141_at -0.0679 0.4488
GSE23400 PSKH1 5681 213141_at -0.1603 0.0001
GSE26886 PSKH1 5681 213141_at 0.2036 0.1073
GSE29001 PSKH1 5681 213141_at -0.2085 0.2520
GSE38129 PSKH1 5681 213141_at -0.0953 0.2513
GSE45670 PSKH1 5681 213141_at -0.0565 0.5490
GSE63941 PSKH1 5681 213141_at -0.4597 0.0525
GSE77861 PSKH1 5681 213141_at -0.1113 0.4807
GSE97050 PSKH1 5681 A_23_P390596 -0.0765 0.7367
SRP007169 PSKH1 5681 RNAseq -0.7666 0.0372
SRP008496 PSKH1 5681 RNAseq -0.4895 0.0716
SRP064894 PSKH1 5681 RNAseq -0.1742 0.4095
SRP133303 PSKH1 5681 RNAseq 0.0738 0.7033
SRP159526 PSKH1 5681 RNAseq -0.0006 0.9980
SRP193095 PSKH1 5681 RNAseq 0.1176 0.3463
SRP219564 PSKH1 5681 RNAseq -0.5815 0.1422
TCGA PSKH1 5681 RNAseq -0.2234 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PSKH1 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of PSKH1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSKH1 5681 9 2 19
GSE20123 PSKH1 5681 9 2 19
GSE43470 PSKH1 5681 1 9 33
GSE46452 PSKH1 5681 38 1 20
GSE47630 PSKH1 5681 11 8 21
GSE54993 PSKH1 5681 2 4 64
GSE54994 PSKH1 5681 8 10 35
GSE60625 PSKH1 5681 4 0 7
GSE74703 PSKH1 5681 1 6 29
GSE74704 PSKH1 5681 5 1 14
TCGA PSKH1 5681 30 12 54

Total number of gains: 118; Total number of losses: 55; Total Number of normals: 315.  


 

Somatic mutations of PSKH1:

 

Generating mutation plots.

 

Highly correlated genes for PSKH1:

 

Showing top 20/335 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSKH1KCND30.798343303
PSKH1ZNF1740.797707303
PSKH1TMEM1290.774973303
PSKH1C16orf580.772609303
PSKH1USP190.769376303
PSKH1GTPBP100.754453303
PSKH1INSRR0.753751303
PSKH1LMO10.73817303
PSKH1RARA0.731009403
PSKH1FLYWCH20.7301303
PSKH1GPA330.728952303
PSKH1ACVRL10.726373403
PSKH1FGF160.724199303
PSKH1SPNS10.719414303
PSKH1DNTTIP10.715748303
PSKH1ZCCHC170.712906303
PSKH1MFSD30.709732303
PSKH1LDHD0.709639303
PSKH1FZR10.708694403
PSKH1TGIF20.706847303

For details and further investigation, click here