| Full name: RAB17, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 64284 | HGNC ID: HGNC:16523 | Ensembl Gene: ENSG00000124839 | OMIM ID: 602206 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB17 | 64284 | 218931_at | -0.2885 | 0.3817 | |
| GSE20347 | RAB17 | 64284 | 218931_at | -0.2855 | 0.0577 | |
| GSE23400 | RAB17 | 64284 | 218931_at | -0.2889 | 0.0000 | |
| GSE26886 | RAB17 | 64284 | 218931_at | -0.4008 | 0.1461 | |
| GSE29001 | RAB17 | 64284 | 218931_at | -0.4946 | 0.0044 | |
| GSE38129 | RAB17 | 64284 | 218931_at | -0.2453 | 0.1577 | |
| GSE45670 | RAB17 | 64284 | 218931_at | -0.1494 | 0.5177 | |
| GSE53622 | RAB17 | 64284 | 82247 | -1.7081 | 0.0000 | |
| GSE53624 | RAB17 | 64284 | 82247 | -1.5432 | 0.0000 | |
| GSE63941 | RAB17 | 64284 | 218931_at | 1.0805 | 0.1403 | |
| GSE77861 | RAB17 | 64284 | 218931_at | -0.2692 | 0.3710 | |
| GSE97050 | RAB17 | 64284 | A_23_P5778 | 0.3597 | 0.1406 | |
| SRP064894 | RAB17 | 64284 | RNAseq | -0.4243 | 0.4908 | |
| SRP133303 | RAB17 | 64284 | RNAseq | -1.0382 | 0.0191 | |
| SRP193095 | RAB17 | 64284 | RNAseq | -1.0271 | 0.0287 | |
| SRP219564 | RAB17 | 64284 | RNAseq | -0.7519 | 0.2798 | |
| TCGA | RAB17 | 64284 | RNAseq | -1.6026 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by RAB17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB17 | 64284 | 1 | 12 | 17 | |
| GSE20123 | RAB17 | 64284 | 1 | 12 | 17 | |
| GSE43470 | RAB17 | 64284 | 1 | 9 | 33 | |
| GSE46452 | RAB17 | 64284 | 0 | 5 | 54 | |
| GSE47630 | RAB17 | 64284 | 4 | 5 | 31 | |
| GSE54993 | RAB17 | 64284 | 3 | 2 | 65 | |
| GSE54994 | RAB17 | 64284 | 8 | 10 | 35 | |
| GSE60625 | RAB17 | 64284 | 0 | 3 | 8 | |
| GSE74703 | RAB17 | 64284 | 1 | 7 | 28 | |
| GSE74704 | RAB17 | 64284 | 1 | 5 | 14 | |
| TCGA | RAB17 | 64284 | 12 | 27 | 57 |
Total number of gains: 32; Total number of losses: 97; Total Number of normals: 359.
Somatic mutations of RAB17:
Generating mutation plots.
Highly correlated genes for RAB17:
Showing top 20/106 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB17 | TGM6 | 0.729936 | 3 | 0 | 3 |
| RAB17 | ZNF568 | 0.725601 | 3 | 0 | 3 |
| RAB17 | IZUMO2 | 0.701984 | 3 | 0 | 3 |
| RAB17 | TMEM217 | 0.70152 | 3 | 0 | 3 |
| RAB17 | POLL | 0.678318 | 4 | 0 | 3 |
| RAB17 | PIWIL2 | 0.672813 | 3 | 0 | 3 |
| RAB17 | UCK1 | 0.668741 | 4 | 0 | 3 |
| RAB17 | LRTM2 | 0.657388 | 3 | 0 | 3 |
| RAB17 | GRIPAP1 | 0.65256 | 3 | 0 | 3 |
| RAB17 | THRSP | 0.645577 | 4 | 0 | 3 |
| RAB17 | CRELD1 | 0.641675 | 3 | 0 | 3 |
| RAB17 | LRFN2 | 0.629746 | 4 | 0 | 3 |
| RAB17 | PNPLA7 | 0.621786 | 4 | 0 | 3 |
| RAB17 | TDRD10 | 0.619501 | 3 | 0 | 3 |
| RAB17 | AKR7A3 | 0.618848 | 5 | 0 | 4 |
| RAB17 | MYH13 | 0.613417 | 5 | 0 | 3 |
| RAB17 | VIPR2 | 0.61337 | 4 | 0 | 3 |
| RAB17 | RGR | 0.6125 | 5 | 0 | 4 |
| RAB17 | CHMP6 | 0.609832 | 4 | 0 | 3 |
| RAB17 | CCL17 | 0.606771 | 5 | 0 | 4 |
For details and further investigation, click here
