TMEM230

 

Full name: transmembrane protein 230 Alias Symbol: HSPC274
Type: protein-coding gene Cytoband: 20p13-p12.3
Entrez ID: 29058 HGNC ID: HGNC:15876 Ensembl Gene: ENSG00000089063 OMIM ID: 617019
Screen Evidence:

 

Expression of TMEM230:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM230 29058 224584_at 0.1368 0.7430
GSE20347 TMEM230 29058 220477_s_at 0.6274 0.0274
GSE23400 TMEM230 29058 220477_s_at 0.6416 0.0000
GSE26886 TMEM230 29058 224584_at 0.6639 0.0072
GSE29001 TMEM230 29058 220477_s_at 0.7101 0.0119
GSE38129 TMEM230 29058 220477_s_at 0.7684 0.0012
GSE45670 TMEM230 29058 224584_at 0.2156 0.2547
GSE53622 TMEM230 29058 100835 0.6758 0.0000
GSE53624 TMEM230 29058 82280 0.6042 0.0000
GSE63941 TMEM230 29058 224584_at -0.5080 0.1179
GSE77861 TMEM230 29058 224584_at 0.7811 0.0071
SRP007169 TMEM230 29058 RNAseq 0.5485 0.1540
SRP008496 TMEM230 29058 RNAseq 0.7824 0.0006
SRP064894 TMEM230 29058 RNAseq 0.5487 0.0012
SRP133303 TMEM230 29058 RNAseq 0.5462 0.0000
SRP159526 TMEM230 29058 RNAseq 0.7428 0.0000
SRP193095 TMEM230 29058 RNAseq 0.2538 0.0842
SRP219564 TMEM230 29058 RNAseq 0.1814 0.7229

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TMEM230 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of TMEM230:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM230 29058 10 3 17
GSE20123 TMEM230 29058 10 3 17
GSE43470 TMEM230 29058 10 1 32
GSE46452 TMEM230 29058 26 1 32
GSE47630 TMEM230 29058 18 4 18
GSE54993 TMEM230 29058 2 14 54
GSE54994 TMEM230 29058 25 2 26
GSE60625 TMEM230 29058 0 0 11
GSE74703 TMEM230 29058 9 1 26
GSE74704 TMEM230 29058 5 1 14
TCGA TMEM230 29058 40 11 45

Total number of gains: 155; Total number of losses: 41; Total Number of normals: 292.  

 

Somatic mutations of TMEM230:

 

Generating mutation plots.

 

Highly correlated genes for TMEM230:

 

Showing top 20/760 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM230TNRC180.74476303
TMEM230ZNF3430.712436404
TMEM230ENKD10.703976303
TMEM230CALU0.688269908
TMEM230KATNA10.671402303
TMEM230VKORC10.667403706
TMEM230TBL1XR10.665079707
TMEM230MAPRE10.664754807
TMEM230RILPL20.6607403
TMEM230LAMA50.65433403
TMEM230PXYLP10.653267403
TMEM230STARD3NL0.650019403
TMEM230COL4A10.649916909
TMEM230COL12A10.649247504
TMEM230PGRMC10.648176505
TMEM230CRLS10.648062706
TMEM230XRN20.647355605
TMEM230APMAP0.6458311109
TMEM230SENP30.64421706
TMEM230COPRS0.642902404

For details and further investigation, click here