COL12A1

 

Full name: collagen type XII alpha 1 chain Alias Symbol: 
Type: protein-coding gene Cytoband: 6q13-q14.1
Entrez ID: 1303 HGNC ID: HGNC:2188 Ensembl Gene: ENSG00000111799 OMIM ID: 120320
Drug and gene relationship at DGIdb

 

Expression of COL12A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 COL12A1 1303 225664_at 0.2683 0.8571
GSE26886 COL12A1 1303 225664_at 3.3770 0.0000
GSE45670 COL12A1 1303 225664_at -0.4065 0.5604
GSE53622 COL12A1 1303 6598 2.0705 0.0000
GSE53624 COL12A1 1303 6598 2.2437 0.0000
GSE63941 COL12A1 1303 225664_at -6.1155 0.0015
GSE77861 COL12A1 1303 225664_at 2.2807 0.0121
GSE97050 COL12A1 1303 A_23_P214168 0.8433 0.2994
SRP007169 COL12A1 1303 RNAseq 6.2200 0.0000
SRP008496 COL12A1 1303 RNAseq 6.5219 0.0000
SRP064894 COL12A1 1303 RNAseq 1.1963 0.0005
SRP133303 COL12A1 1303 RNAseq 2.5142 0.0000
SRP159526 COL12A1 1303 RNAseq 1.0067 0.0029
SRP193095 COL12A1 1303 RNAseq 4.7636 0.0000
SRP219564 COL12A1 1303 RNAseq 0.1758 0.7971
TCGA COL12A1 1303 RNAseq 0.3415 0.0010

Upregulated datasets: 10; Downregulated datasets: 1.  

 

Survival by COL12A1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of COL12A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 COL12A1 1303 1 3 26
GSE20123 COL12A1 1303 1 2 27
GSE43470 COL12A1 1303 3 0 40
GSE46452 COL12A1 1303 2 11 46
GSE47630 COL12A1 1303 8 4 28
GSE54993 COL12A1 1303 3 2 65
GSE54994 COL12A1 1303 8 6 39
GSE60625 COL12A1 1303 0 1 10
GSE74703 COL12A1 1303 3 0 33
GSE74704 COL12A1 1303 0 1 19
TCGA COL12A1 1303 9 20 67

Total number of gains: 38; Total number of losses: 50; Total Number of normals: 400.  

 

Somatic mutations of COL12A1:

 

Generating mutation plots.

 

Highly correlated genes for COL12A1:

 

Showing top 20/1083 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
COL12A1COL6A10.854825909
COL12A1SPARC0.842311909
COL12A1FN10.837008808
COL12A1COL6A30.824193909
COL12A1COL6A20.82047909
COL12A1VCAN0.817562909
COL12A1HTRA10.814179909
COL12A1LUM0.811025909
COL12A1FSTL10.809993909
COL12A1ANTXR10.800817909
COL12A1LGALS10.795251908
COL12A1CTSK0.792429909
COL12A1MMP20.791376807
COL12A1AEBP10.78889909
COL12A1COL3A10.785639908
COL12A1COL5A20.78475909
COL12A1COL8A10.781252909
COL12A1COL5A10.777426909
COL12A1MICAL20.77641606
COL12A1CALU0.775829808

For details and further investigation, click here