| Full name: progesterone receptor membrane component 1 | Alias Symbol: HPR6.6 | ||
| Type: protein-coding gene | Cytoband: Xq24 | ||
| Entrez ID: 10857 | HGNC ID: HGNC:16090 | Ensembl Gene: ENSG00000101856 | OMIM ID: 300435 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PGRMC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGRMC1 | 10857 | 201121_s_at | -0.0250 | 0.9345 | |
| GSE20347 | PGRMC1 | 10857 | 201121_s_at | 0.3748 | 0.0084 | |
| GSE23400 | PGRMC1 | 10857 | 201121_s_at | 0.3862 | 0.0000 | |
| GSE26886 | PGRMC1 | 10857 | 201121_s_at | 0.3905 | 0.0882 | |
| GSE29001 | PGRMC1 | 10857 | 201121_s_at | 0.4822 | 0.0714 | |
| GSE38129 | PGRMC1 | 10857 | 201121_s_at | 0.4356 | 0.0001 | |
| GSE45670 | PGRMC1 | 10857 | 201121_s_at | 0.1608 | 0.3597 | |
| GSE53622 | PGRMC1 | 10857 | 105868 | 0.1150 | 0.1114 | |
| GSE53624 | PGRMC1 | 10857 | 105868 | 0.5369 | 0.0000 | |
| GSE63941 | PGRMC1 | 10857 | 201121_s_at | -0.2731 | 0.4676 | |
| GSE77861 | PGRMC1 | 10857 | 201121_s_at | 0.3323 | 0.2314 | |
| GSE97050 | PGRMC1 | 10857 | A_33_P3332130 | -0.1644 | 0.5183 | |
| SRP007169 | PGRMC1 | 10857 | RNAseq | 0.4438 | 0.2332 | |
| SRP008496 | PGRMC1 | 10857 | RNAseq | 0.7188 | 0.0078 | |
| SRP064894 | PGRMC1 | 10857 | RNAseq | 0.2619 | 0.0752 | |
| SRP133303 | PGRMC1 | 10857 | RNAseq | 0.6987 | 0.0017 | |
| SRP159526 | PGRMC1 | 10857 | RNAseq | 0.7096 | 0.0015 | |
| SRP193095 | PGRMC1 | 10857 | RNAseq | 0.0481 | 0.7794 | |
| SRP219564 | PGRMC1 | 10857 | RNAseq | 0.0975 | 0.8121 | |
| TCGA | PGRMC1 | 10857 | RNAseq | 0.0381 | 0.4141 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PGRMC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGRMC1:
No record found for this gene.
Somatic mutations of PGRMC1:
Generating mutation plots.
Highly correlated genes for PGRMC1:
Showing top 20/939 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGRMC1 | STAT5B | 0.810518 | 3 | 0 | 3 |
| PGRMC1 | TMEM205 | 0.808813 | 3 | 0 | 3 |
| PGRMC1 | UTP23 | 0.790695 | 3 | 0 | 3 |
| PGRMC1 | ZNRF3 | 0.769695 | 3 | 0 | 3 |
| PGRMC1 | RNASE4 | 0.75612 | 3 | 0 | 3 |
| PGRMC1 | RGMB | 0.7535 | 3 | 0 | 3 |
| PGRMC1 | DHRSX | 0.752824 | 3 | 0 | 3 |
| PGRMC1 | ZSCAN21 | 0.746403 | 3 | 0 | 3 |
| PGRMC1 | ITPK1 | 0.740367 | 3 | 0 | 3 |
| PGRMC1 | TOP2B | 0.735544 | 3 | 0 | 3 |
| PGRMC1 | TRIM28 | 0.733492 | 3 | 0 | 3 |
| PGRMC1 | RHOU | 0.731553 | 3 | 0 | 3 |
| PGRMC1 | MYLIP | 0.729057 | 3 | 0 | 3 |
| PGRMC1 | LIX1L | 0.721188 | 3 | 0 | 3 |
| PGRMC1 | ZNF627 | 0.721072 | 3 | 0 | 3 |
| PGRMC1 | KLHL20 | 0.716119 | 3 | 0 | 3 |
| PGRMC1 | TRIM44 | 0.715729 | 4 | 0 | 4 |
| PGRMC1 | DIP2C | 0.703786 | 3 | 0 | 3 |
| PGRMC1 | LRRC58 | 0.69892 | 3 | 0 | 3 |
| PGRMC1 | GAPDH | 0.697575 | 3 | 0 | 3 |
For details and further investigation, click here
