| Full name: transmembrane protein 42 | Alias Symbol: MGC29956 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 131616 | HGNC ID: HGNC:28444 | Ensembl Gene: ENSG00000169964 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM42 | 131616 | 226361_at | -0.2182 | 0.4254 | |
| GSE26886 | TMEM42 | 131616 | 226361_at | -0.1086 | 0.5624 | |
| GSE45670 | TMEM42 | 131616 | 226361_at | -0.0562 | 0.6700 | |
| GSE53622 | TMEM42 | 131616 | 14966 | -0.0486 | 0.5020 | |
| GSE53624 | TMEM42 | 131616 | 14966 | 0.0507 | 0.4602 | |
| GSE63941 | TMEM42 | 131616 | 226361_at | -1.0191 | 0.0063 | |
| GSE77861 | TMEM42 | 131616 | 226361_at | -0.1678 | 0.2487 | |
| GSE97050 | TMEM42 | 131616 | A_23_P29836 | 0.0760 | 0.7635 | |
| SRP007169 | TMEM42 | 131616 | RNAseq | 0.0435 | 0.9330 | |
| SRP008496 | TMEM42 | 131616 | RNAseq | 0.1827 | 0.6310 | |
| SRP064894 | TMEM42 | 131616 | RNAseq | 0.3432 | 0.1694 | |
| SRP133303 | TMEM42 | 131616 | RNAseq | -0.2561 | 0.2044 | |
| SRP159526 | TMEM42 | 131616 | RNAseq | -0.0561 | 0.8029 | |
| SRP193095 | TMEM42 | 131616 | RNAseq | -0.3420 | 0.0087 | |
| SRP219564 | TMEM42 | 131616 | RNAseq | 0.1930 | 0.6688 | |
| TCGA | TMEM42 | 131616 | RNAseq | -0.1014 | 0.2122 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM42 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM42 | 131616 | 0 | 17 | 13 | |
| GSE20123 | TMEM42 | 131616 | 0 | 18 | 12 | |
| GSE43470 | TMEM42 | 131616 | 0 | 21 | 22 | |
| GSE46452 | TMEM42 | 131616 | 2 | 17 | 40 | |
| GSE47630 | TMEM42 | 131616 | 1 | 24 | 15 | |
| GSE54993 | TMEM42 | 131616 | 7 | 2 | 61 | |
| GSE54994 | TMEM42 | 131616 | 0 | 35 | 18 | |
| GSE60625 | TMEM42 | 131616 | 5 | 0 | 6 | |
| GSE74703 | TMEM42 | 131616 | 0 | 16 | 20 | |
| GSE74704 | TMEM42 | 131616 | 0 | 13 | 7 | |
| TCGA | TMEM42 | 131616 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 237; Total Number of normals: 235.
Somatic mutations of TMEM42:
Generating mutation plots.
Highly correlated genes for TMEM42:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM42 | WDR38 | 0.687063 | 3 | 0 | 3 |
| TMEM42 | BCDIN3D | 0.677078 | 3 | 0 | 3 |
| TMEM42 | FENDRR | 0.674017 | 3 | 0 | 3 |
| TMEM42 | HSPB2 | 0.672973 | 3 | 0 | 3 |
| TMEM42 | LINC01082 | 0.655298 | 3 | 0 | 3 |
| TMEM42 | SCN3A | 0.652203 | 3 | 0 | 3 |
| TMEM42 | TCEAL7 | 0.638743 | 3 | 0 | 3 |
| TMEM42 | PDZRN3 | 0.631783 | 3 | 0 | 3 |
| TMEM42 | SHC3 | 0.619337 | 5 | 0 | 4 |
| TMEM42 | CPED1 | 0.618332 | 3 | 0 | 3 |
| TMEM42 | HRCT1 | 0.616194 | 4 | 0 | 3 |
| TMEM42 | CYTL1 | 0.613365 | 3 | 0 | 3 |
| TMEM42 | ZBTB45 | 0.613306 | 3 | 0 | 3 |
| TMEM42 | NPR2 | 0.611233 | 3 | 0 | 3 |
| TMEM42 | PEX12 | 0.608125 | 4 | 0 | 3 |
| TMEM42 | ZNF569 | 0.607044 | 4 | 0 | 4 |
| TMEM42 | MYL4 | 0.603234 | 4 | 0 | 4 |
| TMEM42 | S100A4 | 0.601656 | 3 | 0 | 3 |
| TMEM42 | MAGEL2 | 0.597139 | 4 | 0 | 3 |
| TMEM42 | MAB21L2 | 0.594678 | 4 | 0 | 3 |
For details and further investigation, click here
