| Full name: S100 calcium binding protein A4 | Alias Symbol: P9KA|18A2|PEL98|42A|FSP1 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6275 | HGNC ID: HGNC:10494 | Ensembl Gene: ENSG00000196154 | OMIM ID: 114210 |
| Drug and gene relationship at DGIdb | |||
Expression of S100A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100A4 | 6275 | 203186_s_at | -0.2330 | 0.7283 | |
| GSE20347 | S100A4 | 6275 | 203186_s_at | -0.3304 | 0.1285 | |
| GSE23400 | S100A4 | 6275 | 203186_s_at | -0.5416 | 0.0000 | |
| GSE26886 | S100A4 | 6275 | 203186_s_at | -0.1421 | 0.7145 | |
| GSE29001 | S100A4 | 6275 | 203186_s_at | -0.4797 | 0.1826 | |
| GSE38129 | S100A4 | 6275 | 203186_s_at | -0.6004 | 0.0429 | |
| GSE45670 | S100A4 | 6275 | 203186_s_at | -0.7987 | 0.0024 | |
| GSE53622 | S100A4 | 6275 | 53914 | -0.5039 | 0.0000 | |
| GSE53624 | S100A4 | 6275 | 53914 | -0.4043 | 0.0000 | |
| GSE63941 | S100A4 | 6275 | 203186_s_at | -2.7427 | 0.0600 | |
| GSE77861 | S100A4 | 6275 | 203186_s_at | 0.4636 | 0.2292 | |
| GSE97050 | S100A4 | 6275 | A_23_P94800 | -0.4352 | 0.3566 | |
| SRP007169 | S100A4 | 6275 | RNAseq | 0.3975 | 0.4191 | |
| SRP008496 | S100A4 | 6275 | RNAseq | 0.1625 | 0.6464 | |
| SRP064894 | S100A4 | 6275 | RNAseq | -0.1349 | 0.7406 | |
| SRP133303 | S100A4 | 6275 | RNAseq | -0.1390 | 0.6559 | |
| SRP159526 | S100A4 | 6275 | RNAseq | -0.4724 | 0.1996 | |
| SRP193095 | S100A4 | 6275 | RNAseq | 0.2885 | 0.0986 | |
| SRP219564 | S100A4 | 6275 | RNAseq | 0.0840 | 0.8615 | |
| TCGA | S100A4 | 6275 | RNAseq | 0.0524 | 0.5961 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by S100A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100A4 | 6275 | 14 | 0 | 16 | |
| GSE20123 | S100A4 | 6275 | 14 | 0 | 16 | |
| GSE43470 | S100A4 | 6275 | 6 | 2 | 35 | |
| GSE46452 | S100A4 | 6275 | 2 | 1 | 56 | |
| GSE47630 | S100A4 | 6275 | 15 | 0 | 25 | |
| GSE54993 | S100A4 | 6275 | 0 | 4 | 66 | |
| GSE54994 | S100A4 | 6275 | 16 | 0 | 37 | |
| GSE60625 | S100A4 | 6275 | 0 | 0 | 11 | |
| GSE74703 | S100A4 | 6275 | 6 | 1 | 29 | |
| GSE74704 | S100A4 | 6275 | 7 | 0 | 13 | |
| TCGA | S100A4 | 6275 | 39 | 1 | 56 |
Total number of gains: 119; Total number of losses: 9; Total Number of normals: 360.
Somatic mutations of S100A4:
Generating mutation plots.
Highly correlated genes for S100A4:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100A4 | CDH2 | 0.788276 | 3 | 0 | 3 |
| S100A4 | PAG1 | 0.679126 | 4 | 0 | 4 |
| S100A4 | MEF2C | 0.678307 | 7 | 0 | 7 |
| S100A4 | SCARA5 | 0.675983 | 4 | 0 | 3 |
| S100A4 | LAMA2 | 0.673244 | 9 | 0 | 7 |
| S100A4 | PRAF2 | 0.672582 | 3 | 0 | 3 |
| S100A4 | NAT14 | 0.664447 | 3 | 0 | 3 |
| S100A4 | LAMB2 | 0.658437 | 8 | 0 | 8 |
| S100A4 | YPEL4 | 0.657916 | 3 | 0 | 3 |
| S100A4 | PENK | 0.655427 | 3 | 0 | 3 |
| S100A4 | FCGR2B | 0.653209 | 7 | 0 | 6 |
| S100A4 | VWF | 0.64942 | 7 | 0 | 7 |
| S100A4 | MMP23B | 0.633664 | 3 | 0 | 3 |
| S100A4 | CPQ | 0.633486 | 6 | 0 | 5 |
| S100A4 | TBX2 | 0.633247 | 6 | 0 | 6 |
| S100A4 | APOL4 | 0.633135 | 3 | 0 | 3 |
| S100A4 | SHC3 | 0.631826 | 5 | 0 | 3 |
| S100A4 | SEMA3G | 0.629383 | 5 | 0 | 4 |
| S100A4 | SMIM10 | 0.627333 | 4 | 0 | 4 |
| S100A4 | NACAD | 0.626988 | 4 | 0 | 3 |
For details and further investigation, click here
