| Full name: mab-21 like 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q31.3 | ||
| Entrez ID: 10586 | HGNC ID: HGNC:6758 | Ensembl Gene: ENSG00000181541 | OMIM ID: 604357 |
| Drug and gene relationship at DGIdb | |||
Expression of MAB21L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAB21L2 | 10586 | 210302_s_at | -1.2731 | 0.2281 | |
| GSE20347 | MAB21L2 | 10586 | 210302_s_at | 0.0058 | 0.9525 | |
| GSE23400 | MAB21L2 | 10586 | 210302_s_at | -0.1689 | 0.0000 | |
| GSE26886 | MAB21L2 | 10586 | 210302_s_at | -0.1107 | 0.3346 | |
| GSE29001 | MAB21L2 | 10586 | 210302_s_at | -0.2304 | 0.1973 | |
| GSE38129 | MAB21L2 | 10586 | 210302_s_at | -0.2373 | 0.0298 | |
| GSE45670 | MAB21L2 | 10586 | 210302_s_at | -0.6266 | 0.0013 | |
| GSE53622 | MAB21L2 | 10586 | 54659 | -0.0276 | 0.7369 | |
| GSE53624 | MAB21L2 | 10586 | 54659 | 0.0799 | 0.4648 | |
| GSE63941 | MAB21L2 | 10586 | 210302_s_at | -0.2106 | 0.0921 | |
| GSE77861 | MAB21L2 | 10586 | 210302_s_at | 0.0311 | 0.8357 | |
| GSE97050 | MAB21L2 | 10586 | A_24_P148907 | 0.0067 | 0.9843 | |
| SRP133303 | MAB21L2 | 10586 | RNAseq | -0.5703 | 0.0134 | |
| SRP159526 | MAB21L2 | 10586 | RNAseq | -2.6595 | 0.0009 | |
| SRP193095 | MAB21L2 | 10586 | RNAseq | -0.4639 | 0.0045 | |
| TCGA | MAB21L2 | 10586 | RNAseq | -1.5838 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MAB21L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAB21L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAB21L2 | 10586 | 0 | 13 | 17 | |
| GSE20123 | MAB21L2 | 10586 | 0 | 13 | 17 | |
| GSE43470 | MAB21L2 | 10586 | 0 | 14 | 29 | |
| GSE46452 | MAB21L2 | 10586 | 1 | 36 | 22 | |
| GSE47630 | MAB21L2 | 10586 | 0 | 23 | 17 | |
| GSE54993 | MAB21L2 | 10586 | 10 | 0 | 60 | |
| GSE54994 | MAB21L2 | 10586 | 1 | 12 | 40 | |
| GSE60625 | MAB21L2 | 10586 | 0 | 1 | 10 | |
| GSE74703 | MAB21L2 | 10586 | 0 | 12 | 24 | |
| GSE74704 | MAB21L2 | 10586 | 0 | 7 | 13 | |
| TCGA | MAB21L2 | 10586 | 10 | 35 | 51 |
Total number of gains: 22; Total number of losses: 166; Total Number of normals: 300.
Somatic mutations of MAB21L2:
Generating mutation plots.
Highly correlated genes for MAB21L2:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAB21L2 | GYPE | 0.721088 | 3 | 0 | 3 |
| MAB21L2 | PLA2G2D | 0.719751 | 4 | 0 | 4 |
| MAB21L2 | TRPM8 | 0.707651 | 3 | 0 | 3 |
| MAB21L2 | ZNF763 | 0.696388 | 5 | 0 | 5 |
| MAB21L2 | OBSL1 | 0.686001 | 4 | 0 | 3 |
| MAB21L2 | DRD2 | 0.684808 | 4 | 0 | 3 |
| MAB21L2 | BTNL2 | 0.681473 | 4 | 0 | 4 |
| MAB21L2 | TMEM108 | 0.681366 | 3 | 0 | 3 |
| MAB21L2 | SLC5A4 | 0.679855 | 4 | 0 | 4 |
| MAB21L2 | LPO | 0.676227 | 3 | 0 | 3 |
| MAB21L2 | BAALC | 0.672997 | 3 | 0 | 3 |
| MAB21L2 | CYP2D6 | 0.672433 | 4 | 0 | 3 |
| MAB21L2 | C16orf89 | 0.665399 | 4 | 0 | 3 |
| MAB21L2 | KRT35 | 0.664509 | 4 | 0 | 3 |
| MAB21L2 | ANKDD1A | 0.662761 | 4 | 0 | 3 |
| MAB21L2 | PAX3 | 0.660637 | 4 | 0 | 3 |
| MAB21L2 | MYO1A | 0.65816 | 4 | 0 | 3 |
| MAB21L2 | RNF180 | 0.657153 | 4 | 0 | 4 |
| MAB21L2 | SCNN1G | 0.656483 | 3 | 0 | 3 |
| MAB21L2 | HRC | 0.652073 | 5 | 0 | 4 |
For details and further investigation, click here
