| Full name: transmembrane protein 63A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q42.12 | ||
| Entrez ID: 9725 | HGNC ID: HGNC:29118 | Ensembl Gene: ENSG00000196187 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM63A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE20347 | TMEM63A | 9725 | 202700_s_at | 0.1127 | 0.2410 | |
| GSE23400 | TMEM63A | 9725 | 202699_s_at | -0.1314 | 0.0038 | |
| GSE29001 | TMEM63A | 9725 | 214833_at | 0.5691 | 0.0315 | |
| GSE38129 | TMEM63A | 9725 | 202700_s_at | -0.0234 | 0.7988 | |
| GSE53622 | TMEM63A | 9725 | 88705 | -0.0168 | 0.7990 | |
| GSE53624 | TMEM63A | 9725 | 88705 | -0.0550 | 0.3917 | |
| GSE63941 | TMEM63A | 9725 | 202699_s_at | 0.7433 | 0.0796 | |
| GSE77861 | TMEM63A | 9725 | 215583_at | -0.0292 | 0.8649 | |
| GSE97050 | TMEM63A | 9725 | A_23_P200489 | 0.0639 | 0.8111 | |
| SRP007169 | TMEM63A | 9725 | RNAseq | 0.4477 | 0.2483 | |
| SRP008496 | TMEM63A | 9725 | RNAseq | 0.3902 | 0.1500 | |
| SRP064894 | TMEM63A | 9725 | RNAseq | -0.0233 | 0.8985 | |
| SRP133303 | TMEM63A | 9725 | RNAseq | -0.4063 | 0.0092 | |
| SRP159526 | TMEM63A | 9725 | RNAseq | 0.2815 | 0.5859 | |
| SRP193095 | TMEM63A | 9725 | RNAseq | 0.3432 | 0.2380 | |
| SRP219564 | TMEM63A | 9725 | RNAseq | -0.0708 | 0.8145 | |
| TCGA | TMEM63A | 9725 | RNAseq | -0.2815 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM63A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM63A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM63A | 9725 | 11 | 0 | 19 | |
| GSE20123 | TMEM63A | 9725 | 11 | 0 | 19 | |
| GSE43470 | TMEM63A | 9725 | 7 | 1 | 35 | |
| GSE46452 | TMEM63A | 9725 | 3 | 1 | 55 | |
| GSE47630 | TMEM63A | 9725 | 15 | 0 | 25 | |
| GSE54993 | TMEM63A | 9725 | 0 | 6 | 64 | |
| GSE54994 | TMEM63A | 9725 | 16 | 0 | 37 | |
| GSE60625 | TMEM63A | 9725 | 0 | 0 | 11 | |
| GSE74703 | TMEM63A | 9725 | 7 | 1 | 28 | |
| GSE74704 | TMEM63A | 9725 | 5 | 0 | 15 | |
| TCGA | TMEM63A | 9725 | 46 | 3 | 47 |
Total number of gains: 121; Total number of losses: 12; Total Number of normals: 355.
Somatic mutations of TMEM63A:
Generating mutation plots.
Highly correlated genes for TMEM63A:
Showing top 20/56 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM63A | ASRGL1 | 0.786279 | 3 | 0 | 3 |
| TMEM63A | TMEM102 | 0.774504 | 3 | 0 | 3 |
| TMEM63A | ANGPT4 | 0.759158 | 3 | 0 | 3 |
| TMEM63A | RCOR2 | 0.758773 | 3 | 0 | 3 |
| TMEM63A | LRFN2 | 0.750149 | 3 | 0 | 3 |
| TMEM63A | CNTD2 | 0.749063 | 3 | 0 | 3 |
| TMEM63A | RGP1 | 0.7468 | 3 | 0 | 3 |
| TMEM63A | RASSF7 | 0.724963 | 3 | 0 | 3 |
| TMEM63A | CCDC57 | 0.708336 | 3 | 0 | 3 |
| TMEM63A | KAT2A | 0.702103 | 3 | 0 | 3 |
| TMEM63A | NPR1 | 0.699935 | 3 | 0 | 3 |
| TMEM63A | NEFH | 0.697405 | 3 | 0 | 3 |
| TMEM63A | HOXD9 | 0.694258 | 4 | 0 | 3 |
| TMEM63A | CYP2A13 | 0.693183 | 4 | 0 | 4 |
| TMEM63A | HAUS5 | 0.678562 | 3 | 0 | 3 |
| TMEM63A | GDPD5 | 0.67101 | 3 | 0 | 3 |
| TMEM63A | SNTG2 | 0.66527 | 3 | 0 | 3 |
| TMEM63A | GPR39 | 0.658049 | 3 | 0 | 3 |
| TMEM63A | KCNN4 | 0.657909 | 4 | 0 | 3 |
| TMEM63A | PCP2 | 0.657804 | 3 | 0 | 3 |
For details and further investigation, click here
