| Full name: coiled-coil domain containing 57 | Alias Symbol: FLJ00130|FLJ23754 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 284001 | HGNC ID: HGNC:27564 | Ensembl Gene: ENSG00000176155 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC57:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC57 | 284001 | 227783_at | -0.0951 | 0.8186 | |
| GSE20347 | CCDC57 | 284001 | 214818_at | 0.0497 | 0.5768 | |
| GSE23400 | CCDC57 | 284001 | 214818_at | -0.0087 | 0.7636 | |
| GSE26886 | CCDC57 | 284001 | 214818_at | 0.4023 | 0.0023 | |
| GSE29001 | CCDC57 | 284001 | 214818_at | 0.1076 | 0.5532 | |
| GSE38129 | CCDC57 | 284001 | 214818_at | -0.0596 | 0.5583 | |
| GSE45670 | CCDC57 | 284001 | 227783_at | -0.1316 | 0.3158 | |
| GSE53622 | CCDC57 | 284001 | 18423 | 0.3411 | 0.0000 | |
| GSE53624 | CCDC57 | 284001 | 18423 | 0.0872 | 0.0748 | |
| GSE63941 | CCDC57 | 284001 | 227783_at | 0.5812 | 0.3143 | |
| GSE77861 | CCDC57 | 284001 | 227783_at | -0.1626 | 0.3968 | |
| GSE97050 | CCDC57 | 284001 | A_33_P3351664 | 0.1906 | 0.4194 | |
| SRP007169 | CCDC57 | 284001 | RNAseq | 0.3427 | 0.5465 | |
| SRP008496 | CCDC57 | 284001 | RNAseq | 0.5738 | 0.1232 | |
| SRP064894 | CCDC57 | 284001 | RNAseq | 0.7525 | 0.0000 | |
| SRP133303 | CCDC57 | 284001 | RNAseq | 0.3755 | 0.0049 | |
| SRP159526 | CCDC57 | 284001 | RNAseq | 0.8657 | 0.0409 | |
| SRP193095 | CCDC57 | 284001 | RNAseq | 0.9410 | 0.0000 | |
| SRP219564 | CCDC57 | 284001 | RNAseq | 0.5628 | 0.0076 | |
| TCGA | CCDC57 | 284001 | RNAseq | -0.0477 | 0.4744 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC57 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC57:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC57 | 284001 | 4 | 5 | 21 | |
| GSE20123 | CCDC57 | 284001 | 4 | 5 | 21 | |
| GSE43470 | CCDC57 | 284001 | 3 | 5 | 35 | |
| GSE46452 | CCDC57 | 284001 | 34 | 0 | 25 | |
| GSE47630 | CCDC57 | 284001 | 9 | 2 | 29 | |
| GSE54993 | CCDC57 | 284001 | 2 | 5 | 63 | |
| GSE54994 | CCDC57 | 284001 | 10 | 6 | 37 | |
| GSE60625 | CCDC57 | 284001 | 6 | 0 | 5 | |
| GSE74703 | CCDC57 | 284001 | 3 | 3 | 30 | |
| GSE74704 | CCDC57 | 284001 | 4 | 4 | 12 | |
| TCGA | CCDC57 | 284001 | 24 | 13 | 59 |
Total number of gains: 103; Total number of losses: 48; Total Number of normals: 337.
Somatic mutations of CCDC57:
Generating mutation plots.
Highly correlated genes for CCDC57:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC57 | ADAP1 | 0.756426 | 3 | 0 | 3 |
| CCDC57 | C19orf81 | 0.753952 | 3 | 0 | 3 |
| CCDC57 | SHOX2 | 0.730424 | 3 | 0 | 3 |
| CCDC57 | ARVCF | 0.717942 | 5 | 0 | 5 |
| CCDC57 | KIF26A | 0.709732 | 3 | 0 | 3 |
| CCDC57 | TMEM63A | 0.708336 | 3 | 0 | 3 |
| CCDC57 | PAQR6 | 0.698292 | 3 | 0 | 3 |
| CCDC57 | RAB3IL1 | 0.693581 | 4 | 0 | 3 |
| CCDC57 | AICDA | 0.681718 | 3 | 0 | 3 |
| CCDC57 | COL20A1 | 0.679368 | 3 | 0 | 3 |
| CCDC57 | CLECL1 | 0.677028 | 3 | 0 | 3 |
| CCDC57 | NLRP6 | 0.675541 | 3 | 0 | 3 |
| CCDC57 | PLCH2 | 0.670699 | 4 | 0 | 4 |
| CCDC57 | RASGEF1A | 0.664616 | 3 | 0 | 3 |
| CCDC57 | LELP1 | 0.66162 | 4 | 0 | 3 |
| CCDC57 | CCL27 | 0.6605 | 4 | 0 | 3 |
| CCDC57 | CHRNA10 | 0.654632 | 5 | 0 | 5 |
| CCDC57 | WRNIP1 | 0.653166 | 4 | 0 | 3 |
| CCDC57 | SPINT3 | 0.651975 | 4 | 0 | 3 |
| CCDC57 | ZIC1 | 0.65098 | 4 | 0 | 3 |
For details and further investigation, click here
