| Full name: proteasome 26S subunit, non-ATPase 12 | Alias Symbol: p55|Rpn5 | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 5718 | HGNC ID: HGNC:9557 | Ensembl Gene: ENSG00000197170 | OMIM ID: 604450 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMD12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMD12 | 5718 | 202352_s_at | 0.3084 | 0.3960 | |
| GSE20347 | PSMD12 | 5718 | 202352_s_at | 0.4022 | 0.0218 | |
| GSE23400 | PSMD12 | 5718 | 202352_s_at | 0.6703 | 0.0000 | |
| GSE26886 | PSMD12 | 5718 | 202352_s_at | -0.1923 | 0.2818 | |
| GSE29001 | PSMD12 | 5718 | 202352_s_at | 0.4845 | 0.1172 | |
| GSE38129 | PSMD12 | 5718 | 202352_s_at | 0.6104 | 0.0000 | |
| GSE45670 | PSMD12 | 5718 | 202352_s_at | 0.5458 | 0.0020 | |
| GSE53622 | PSMD12 | 5718 | 23066 | 0.2832 | 0.0000 | |
| GSE53624 | PSMD12 | 5718 | 23066 | 0.4944 | 0.0000 | |
| GSE63941 | PSMD12 | 5718 | 202352_s_at | 0.7566 | 0.0267 | |
| GSE77861 | PSMD12 | 5718 | 202352_s_at | 0.7398 | 0.0028 | |
| GSE97050 | PSMD12 | 5718 | A_32_P12639 | 0.1742 | 0.5041 | |
| SRP007169 | PSMD12 | 5718 | RNAseq | 0.3168 | 0.3633 | |
| SRP008496 | PSMD12 | 5718 | RNAseq | 0.4919 | 0.0130 | |
| SRP064894 | PSMD12 | 5718 | RNAseq | 0.3592 | 0.0291 | |
| SRP133303 | PSMD12 | 5718 | RNAseq | 0.5997 | 0.0003 | |
| SRP159526 | PSMD12 | 5718 | RNAseq | 0.2494 | 0.3181 | |
| SRP193095 | PSMD12 | 5718 | RNAseq | 0.0744 | 0.4026 | |
| SRP219564 | PSMD12 | 5718 | RNAseq | 0.2714 | 0.4150 | |
| TCGA | PSMD12 | 5718 | RNAseq | 0.1842 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMD12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMD12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMD12 | 5718 | 3 | 2 | 25 | |
| GSE20123 | PSMD12 | 5718 | 3 | 2 | 25 | |
| GSE43470 | PSMD12 | 5718 | 5 | 0 | 38 | |
| GSE46452 | PSMD12 | 5718 | 31 | 1 | 27 | |
| GSE47630 | PSMD12 | 5718 | 7 | 1 | 32 | |
| GSE54993 | PSMD12 | 5718 | 2 | 5 | 63 | |
| GSE54994 | PSMD12 | 5718 | 9 | 4 | 40 | |
| GSE60625 | PSMD12 | 5718 | 4 | 2 | 5 | |
| GSE74703 | PSMD12 | 5718 | 5 | 0 | 31 | |
| GSE74704 | PSMD12 | 5718 | 3 | 1 | 16 | |
| TCGA | PSMD12 | 5718 | 28 | 8 | 60 |
Total number of gains: 100; Total number of losses: 26; Total Number of normals: 362.
Somatic mutations of PSMD12:
Generating mutation plots.
Highly correlated genes for PSMD12:
Showing top 20/1311 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMD12 | LRRC58 | 0.796933 | 3 | 0 | 3 |
| PSMD12 | NOL11 | 0.772453 | 11 | 0 | 11 |
| PSMD12 | LRRC59 | 0.745878 | 8 | 0 | 8 |
| PSMD12 | TMEM65 | 0.734105 | 3 | 0 | 3 |
| PSMD12 | NMT1 | 0.734009 | 12 | 0 | 11 |
| PSMD12 | RNF130 | 0.731956 | 3 | 0 | 3 |
| PSMD12 | EBNA1BP2 | 0.730836 | 3 | 0 | 3 |
| PSMD12 | PSMD14 | 0.729008 | 11 | 0 | 11 |
| PSMD12 | C14orf119 | 0.728043 | 3 | 0 | 3 |
| PSMD12 | RPA2 | 0.726975 | 3 | 0 | 3 |
| PSMD12 | RNF145 | 0.721691 | 4 | 0 | 4 |
| PSMD12 | ANKRD13C | 0.721104 | 3 | 0 | 3 |
| PSMD12 | PPWD1 | 0.71588 | 3 | 0 | 3 |
| PSMD12 | KPNA2 | 0.708834 | 9 | 0 | 8 |
| PSMD12 | TRADD | 0.708501 | 4 | 0 | 3 |
| PSMD12 | RRP36 | 0.706584 | 4 | 0 | 4 |
| PSMD12 | PTRH2 | 0.704338 | 11 | 0 | 11 |
| PSMD12 | PSMD11 | 0.701982 | 11 | 0 | 10 |
| PSMD12 | KTI12 | 0.700366 | 3 | 0 | 3 |
| PSMD12 | PHB | 0.699054 | 9 | 0 | 8 |
For details and further investigation, click here
