| Full name: ganglioside induced differentiation associated protein 1 | Alias Symbol: CMT4|CMT2K | ||
| Type: protein-coding gene | Cytoband: 8q21.11 | ||
| Entrez ID: 54332 | HGNC ID: HGNC:15968 | Ensembl Gene: ENSG00000104381 | OMIM ID: 606598 |
| Drug and gene relationship at DGIdb | |||
Expression of GDAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDAP1 | 54332 | 226271_at | 0.9728 | 0.2653 | |
| GSE20347 | GDAP1 | 54332 | 221279_at | 0.1395 | 0.0494 | |
| GSE23400 | GDAP1 | 54332 | 221279_at | 0.1094 | 0.0028 | |
| GSE26886 | GDAP1 | 54332 | 226271_at | 0.5836 | 0.1350 | |
| GSE29001 | GDAP1 | 54332 | 221279_at | 0.0538 | 0.6478 | |
| GSE38129 | GDAP1 | 54332 | 221279_at | 0.2428 | 0.0002 | |
| GSE45670 | GDAP1 | 54332 | 226269_at | 0.6588 | 0.0439 | |
| GSE63941 | GDAP1 | 54332 | 226269_at | 0.7878 | 0.3086 | |
| GSE77861 | GDAP1 | 54332 | 226271_at | 0.6599 | 0.1408 | |
| GSE97050 | GDAP1 | 54332 | A_33_P3422659 | 0.4024 | 0.2066 | |
| SRP007169 | GDAP1 | 54332 | RNAseq | 1.4273 | 0.0469 | |
| SRP008496 | GDAP1 | 54332 | RNAseq | 1.8130 | 0.0013 | |
| SRP064894 | GDAP1 | 54332 | RNAseq | 1.2346 | 0.0000 | |
| SRP133303 | GDAP1 | 54332 | RNAseq | 0.7664 | 0.0129 | |
| SRP159526 | GDAP1 | 54332 | RNAseq | 0.9458 | 0.0000 | |
| SRP193095 | GDAP1 | 54332 | RNAseq | 0.8952 | 0.0000 | |
| SRP219564 | GDAP1 | 54332 | RNAseq | 0.8635 | 0.0248 | |
| TCGA | GDAP1 | 54332 | RNAseq | 0.3729 | 0.0023 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by GDAP1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GDAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDAP1 | 54332 | 15 | 1 | 14 | |
| GSE20123 | GDAP1 | 54332 | 16 | 1 | 13 | |
| GSE43470 | GDAP1 | 54332 | 19 | 1 | 23 | |
| GSE46452 | GDAP1 | 54332 | 22 | 0 | 37 | |
| GSE47630 | GDAP1 | 54332 | 23 | 0 | 17 | |
| GSE54993 | GDAP1 | 54332 | 0 | 19 | 51 | |
| GSE54994 | GDAP1 | 54332 | 30 | 0 | 23 | |
| GSE60625 | GDAP1 | 54332 | 0 | 4 | 7 | |
| GSE74703 | GDAP1 | 54332 | 16 | 1 | 19 | |
| GSE74704 | GDAP1 | 54332 | 11 | 0 | 9 | |
| TCGA | GDAP1 | 54332 | 50 | 2 | 44 |
Total number of gains: 202; Total number of losses: 29; Total Number of normals: 257.
Somatic mutations of GDAP1:
Generating mutation plots.
Highly correlated genes for GDAP1:
Showing top 20/632 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDAP1 | ELOF1 | 0.79243 | 3 | 0 | 3 |
| GDAP1 | TMEM65 | 0.791237 | 3 | 0 | 3 |
| GDAP1 | TRIM35 | 0.758718 | 3 | 0 | 3 |
| GDAP1 | SLCO4C1 | 0.758322 | 3 | 0 | 3 |
| GDAP1 | HAUS2 | 0.745388 | 3 | 0 | 3 |
| GDAP1 | ZFP90 | 0.742965 | 3 | 0 | 3 |
| GDAP1 | DHTKD1 | 0.734484 | 3 | 0 | 3 |
| GDAP1 | PUM1 | 0.733458 | 3 | 0 | 3 |
| GDAP1 | NLK | 0.73231 | 3 | 0 | 3 |
| GDAP1 | SCN8A | 0.725642 | 3 | 0 | 3 |
| GDAP1 | ZNF787 | 0.722218 | 3 | 0 | 3 |
| GDAP1 | MRPL41 | 0.720899 | 3 | 0 | 3 |
| GDAP1 | SLC35E1 | 0.718006 | 3 | 0 | 3 |
| GDAP1 | MCM8 | 0.716756 | 3 | 0 | 3 |
| GDAP1 | DHX36 | 0.714694 | 4 | 0 | 4 |
| GDAP1 | EXOSC4 | 0.71426 | 5 | 0 | 4 |
| GDAP1 | TBC1D16 | 0.713093 | 3 | 0 | 3 |
| GDAP1 | NUDT5 | 0.710077 | 3 | 0 | 3 |
| GDAP1 | MZT2B | 0.709883 | 3 | 0 | 3 |
| GDAP1 | COX16 | 0.706745 | 3 | 0 | 3 |
For details and further investigation, click here
