| Full name: transmembrane protein 89 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 440955 | HGNC ID: HGNC:32372 | Ensembl Gene: ENSG00000183396 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM89:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TMEM89 | 440955 | 4958 | 0.1797 | 0.0020 | |
| GSE53624 | TMEM89 | 440955 | 4958 | 0.1192 | 0.1101 | |
| GSE97050 | TMEM89 | 440955 | A_23_P121282 | -0.0049 | 0.9848 | |
| TCGA | TMEM89 | 440955 | RNAseq | -2.0457 | 0.0303 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM89 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM89:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM89 | 440955 | 0 | 18 | 12 | |
| GSE20123 | TMEM89 | 440955 | 0 | 19 | 11 | |
| GSE43470 | TMEM89 | 440955 | 0 | 19 | 24 | |
| GSE46452 | TMEM89 | 440955 | 3 | 16 | 40 | |
| GSE47630 | TMEM89 | 440955 | 1 | 24 | 15 | |
| GSE54993 | TMEM89 | 440955 | 6 | 2 | 62 | |
| GSE54994 | TMEM89 | 440955 | 0 | 36 | 17 | |
| GSE60625 | TMEM89 | 440955 | 5 | 0 | 6 | |
| GSE74703 | TMEM89 | 440955 | 0 | 15 | 21 | |
| GSE74704 | TMEM89 | 440955 | 0 | 12 | 8 | |
| TCGA | TMEM89 | 440955 | 0 | 78 | 18 |
Total number of gains: 15; Total number of losses: 239; Total Number of normals: 234.
Somatic mutations of TMEM89:
Generating mutation plots.
Highly correlated genes for TMEM89:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM89 | VWA5B2 | 0.747638 | 3 | 0 | 3 |
| TMEM89 | C1QL2 | 0.742407 | 3 | 0 | 3 |
| TMEM89 | SHISA7 | 0.740866 | 3 | 0 | 3 |
| TMEM89 | NPPB | 0.735551 | 3 | 0 | 3 |
| TMEM89 | KRT25 | 0.735164 | 3 | 0 | 3 |
| TMEM89 | FFAR1 | 0.734241 | 3 | 0 | 3 |
| TMEM89 | MEGF11 | 0.733719 | 3 | 0 | 3 |
| TMEM89 | SLC26A1 | 0.721111 | 3 | 0 | 3 |
| TMEM89 | PLA2G2C | 0.719747 | 3 | 0 | 3 |
| TMEM89 | GPR32 | 0.718834 | 3 | 0 | 3 |
| TMEM89 | MC3R | 0.718686 | 3 | 0 | 3 |
| TMEM89 | PNLIPRP1 | 0.714265 | 3 | 0 | 3 |
| TMEM89 | ATCAY | 0.708539 | 3 | 0 | 3 |
| TMEM89 | PRDM13 | 0.705547 | 3 | 0 | 3 |
| TMEM89 | GRIK4 | 0.705281 | 3 | 0 | 3 |
| TMEM89 | STAC3 | 0.705137 | 3 | 0 | 3 |
| TMEM89 | FOXA3 | 0.701934 | 3 | 0 | 3 |
| TMEM89 | SLC6A3 | 0.701542 | 3 | 0 | 3 |
| TMEM89 | MS4A18 | 0.699863 | 3 | 0 | 3 |
| TMEM89 | AQP4 | 0.697895 | 3 | 0 | 3 |
For details and further investigation, click here
