| Full name: keratin 25 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 147183 | HGNC ID: HGNC:30839 | Ensembl Gene: ENSG00000204897 | OMIM ID: 616646 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT25 | 147183 | 237905_at | 0.2024 | 0.2872 | |
| GSE26886 | KRT25 | 147183 | 237905_at | 0.0490 | 0.6988 | |
| GSE45670 | KRT25 | 147183 | 237905_at | 0.0948 | 0.1708 | |
| GSE53622 | KRT25 | 147183 | 8292 | 0.0995 | 0.3026 | |
| GSE53624 | KRT25 | 147183 | 8292 | 0.1102 | 0.2546 | |
| GSE63941 | KRT25 | 147183 | 237905_at | 0.0962 | 0.5345 | |
| GSE77861 | KRT25 | 147183 | 237905_at | 0.0488 | 0.5936 | |
| GSE97050 | KRT25 | 147183 | A_23_P15786 | 0.1298 | 0.6214 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRT25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT25 | 147183 | 7 | 1 | 22 | |
| GSE20123 | KRT25 | 147183 | 7 | 1 | 22 | |
| GSE43470 | KRT25 | 147183 | 1 | 2 | 40 | |
| GSE46452 | KRT25 | 147183 | 34 | 0 | 25 | |
| GSE47630 | KRT25 | 147183 | 8 | 1 | 31 | |
| GSE54993 | KRT25 | 147183 | 3 | 4 | 63 | |
| GSE54994 | KRT25 | 147183 | 8 | 5 | 40 | |
| GSE60625 | KRT25 | 147183 | 4 | 0 | 7 | |
| GSE74703 | KRT25 | 147183 | 1 | 1 | 34 | |
| GSE74704 | KRT25 | 147183 | 5 | 1 | 14 | |
| TCGA | KRT25 | 147183 | 22 | 8 | 66 |
Total number of gains: 100; Total number of losses: 24; Total Number of normals: 364.
Somatic mutations of KRT25:
Generating mutation plots.
Highly correlated genes for KRT25:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT25 | CELF4 | 0.831091 | 3 | 0 | 3 |
| KRT25 | OR4C6 | 0.750394 | 3 | 0 | 3 |
| KRT25 | RELB | 0.739753 | 3 | 0 | 3 |
| KRT25 | TMEM89 | 0.735164 | 3 | 0 | 3 |
| KRT25 | BMF | 0.721068 | 3 | 0 | 3 |
| KRT25 | C8G | 0.717528 | 3 | 0 | 3 |
| KRT25 | OR4A15 | 0.712815 | 3 | 0 | 3 |
| KRT25 | LAYN | 0.704212 | 3 | 0 | 3 |
| KRT25 | FAM71A | 0.700496 | 3 | 0 | 3 |
| KRT25 | FAM181B | 0.688921 | 3 | 0 | 3 |
| KRT25 | TM6SF2 | 0.678443 | 3 | 0 | 3 |
| KRT25 | C2orf81 | 0.676214 | 3 | 0 | 3 |
| KRT25 | ITPKA | 0.67448 | 3 | 0 | 3 |
| KRT25 | SSX3 | 0.667037 | 3 | 0 | 3 |
| KRT25 | ALPL | 0.664781 | 3 | 0 | 3 |
| KRT25 | SALL4 | 0.658584 | 3 | 0 | 3 |
| KRT25 | CLEC1B | 0.651924 | 4 | 0 | 3 |
| KRT25 | RUNDC3A | 0.651048 | 3 | 0 | 3 |
| KRT25 | DBF4B | 0.650136 | 4 | 0 | 3 |
| KRT25 | PLA2G2C | 0.649899 | 3 | 0 | 3 |
For details and further investigation, click here
