| Full name: heparan sulfate 6-O-sulfotransferase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q32.1 | ||
| Entrez ID: 266722 | HGNC ID: HGNC:19134 | Ensembl Gene: ENSG00000185352 | OMIM ID: 609401 |
| Drug and gene relationship at DGIdb | |||
Expression of HS6ST3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HS6ST3 | 266722 | 232276_at | -0.3184 | 0.6439 | |
| GSE26886 | HS6ST3 | 266722 | 1552842_at | 0.0592 | 0.5430 | |
| GSE45670 | HS6ST3 | 266722 | 232276_at | -0.3363 | 0.0015 | |
| GSE53622 | HS6ST3 | 266722 | 11945 | -0.8908 | 0.0000 | |
| GSE53624 | HS6ST3 | 266722 | 11945 | -0.3395 | 0.0093 | |
| GSE63941 | HS6ST3 | 266722 | 232276_at | 0.1088 | 0.5654 | |
| GSE77861 | HS6ST3 | 266722 | 1552842_at | -0.2320 | 0.0716 | |
| GSE97050 | HS6ST3 | 266722 | A_23_P32629 | -0.8950 | 0.3584 | |
| SRP133303 | HS6ST3 | 266722 | RNAseq | 1.9742 | 0.0608 | |
| TCGA | HS6ST3 | 266722 | RNAseq | -2.0609 | 0.0016 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by HS6ST3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HS6ST3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HS6ST3 | 266722 | 4 | 9 | 17 | |
| GSE20123 | HS6ST3 | 266722 | 4 | 8 | 18 | |
| GSE43470 | HS6ST3 | 266722 | 4 | 12 | 27 | |
| GSE46452 | HS6ST3 | 266722 | 0 | 32 | 27 | |
| GSE47630 | HS6ST3 | 266722 | 3 | 26 | 11 | |
| GSE54993 | HS6ST3 | 266722 | 11 | 3 | 56 | |
| GSE54994 | HS6ST3 | 266722 | 3 | 13 | 37 | |
| GSE60625 | HS6ST3 | 266722 | 0 | 3 | 8 | |
| GSE74703 | HS6ST3 | 266722 | 3 | 10 | 23 | |
| GSE74704 | HS6ST3 | 266722 | 2 | 8 | 10 | |
| TCGA | HS6ST3 | 266722 | 12 | 35 | 49 |
Total number of gains: 46; Total number of losses: 159; Total Number of normals: 283.
Somatic mutations of HS6ST3:
Generating mutation plots.
Highly correlated genes for HS6ST3:
Showing top 20/265 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HS6ST3 | PDE4DIP | 0.735533 | 3 | 0 | 3 |
| HS6ST3 | CITED1 | 0.717198 | 3 | 0 | 3 |
| HS6ST3 | MYOM2 | 0.709056 | 3 | 0 | 3 |
| HS6ST3 | PLA2G5 | 0.704962 | 3 | 0 | 3 |
| HS6ST3 | NRXN3 | 0.70305 | 4 | 0 | 4 |
| HS6ST3 | TMEM8B | 0.702654 | 5 | 0 | 3 |
| HS6ST3 | DENND2A | 0.701536 | 5 | 0 | 5 |
| HS6ST3 | SMAD9 | 0.700975 | 4 | 0 | 4 |
| HS6ST3 | MYOM1 | 0.699194 | 5 | 0 | 5 |
| HS6ST3 | RYR2 | 0.698019 | 4 | 0 | 4 |
| HS6ST3 | STK33 | 0.696642 | 4 | 0 | 3 |
| HS6ST3 | STK32A | 0.693733 | 4 | 0 | 3 |
| HS6ST3 | KCNN3 | 0.68792 | 4 | 0 | 3 |
| HS6ST3 | CADPS2 | 0.686689 | 3 | 0 | 3 |
| HS6ST3 | SLC22A17 | 0.685564 | 3 | 0 | 3 |
| HS6ST3 | ZMAT4 | 0.682818 | 4 | 0 | 3 |
| HS6ST3 | EEPD1 | 0.679416 | 3 | 0 | 3 |
| HS6ST3 | P2RX2 | 0.678875 | 4 | 0 | 3 |
| HS6ST3 | TTLL7 | 0.678568 | 4 | 0 | 3 |
| HS6ST3 | WFDC3 | 0.678067 | 3 | 0 | 3 |
For details and further investigation, click here
