| Full name: histocompatibility minor HB-1 | Alias Symbol: HB-1|HB-1Y | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 57824 | HGNC ID: HGNC:29677 | Ensembl Gene: ENSG00000158497 | OMIM ID: 609961 |
| Drug and gene relationship at DGIdb | |||
Expression of HMHB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMHB1 | 57824 | 208302_at | -0.0110 | 0.9698 | |
| GSE20347 | HMHB1 | 57824 | 208302_at | -0.0690 | 0.2617 | |
| GSE23400 | HMHB1 | 57824 | 208302_at | -0.0432 | 0.0425 | |
| GSE26886 | HMHB1 | 57824 | 208302_at | 0.1277 | 0.2946 | |
| GSE29001 | HMHB1 | 57824 | 208302_at | -0.0215 | 0.9056 | |
| GSE38129 | HMHB1 | 57824 | 208302_at | -0.0705 | 0.1507 | |
| GSE45670 | HMHB1 | 57824 | 208302_at | 0.0599 | 0.4904 | |
| GSE53622 | HMHB1 | 57824 | 133628 | -1.5652 | 0.0000 | |
| GSE53624 | HMHB1 | 57824 | 133628 | -1.2986 | 0.0000 | |
| GSE63941 | HMHB1 | 57824 | 208302_at | -0.0086 | 0.9541 | |
| GSE77861 | HMHB1 | 57824 | 208302_at | -0.1701 | 0.2057 | |
| GSE97050 | HMHB1 | 57824 | A_23_P30204 | -1.2394 | 0.1084 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HMHB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMHB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HMHB1 | 57824 | 1 | 12 | 17 | |
| GSE20123 | HMHB1 | 57824 | 1 | 12 | 17 | |
| GSE43470 | HMHB1 | 57824 | 2 | 10 | 31 | |
| GSE46452 | HMHB1 | 57824 | 0 | 27 | 32 | |
| GSE47630 | HMHB1 | 57824 | 0 | 20 | 20 | |
| GSE54993 | HMHB1 | 57824 | 9 | 1 | 60 | |
| GSE54994 | HMHB1 | 57824 | 2 | 14 | 37 | |
| GSE60625 | HMHB1 | 57824 | 0 | 0 | 11 | |
| GSE74703 | HMHB1 | 57824 | 2 | 7 | 27 | |
| GSE74704 | HMHB1 | 57824 | 1 | 6 | 13 | |
| TCGA | HMHB1 | 57824 | 3 | 38 | 55 |
Total number of gains: 21; Total number of losses: 147; Total Number of normals: 320.
Somatic mutations of HMHB1:
Generating mutation plots.
Highly correlated genes for HMHB1:
Showing top 20/479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMHB1 | MYOCD | 0.864393 | 3 | 0 | 3 |
| HMHB1 | DES | 0.851969 | 3 | 0 | 3 |
| HMHB1 | ATP1A2 | 0.830712 | 3 | 0 | 3 |
| HMHB1 | RBPMS | 0.829346 | 3 | 0 | 3 |
| HMHB1 | ACTBL2 | 0.82619 | 3 | 0 | 3 |
| HMHB1 | VMAC | 0.82195 | 3 | 0 | 3 |
| HMHB1 | SCN7A | 0.772283 | 4 | 0 | 4 |
| HMHB1 | RAB9B | 0.764778 | 3 | 0 | 3 |
| HMHB1 | MEIS1 | 0.763284 | 3 | 0 | 3 |
| HMHB1 | PTCHD1 | 0.749999 | 3 | 0 | 3 |
| HMHB1 | SGCA | 0.744389 | 4 | 0 | 4 |
| HMHB1 | MAMDC2 | 0.744184 | 3 | 0 | 3 |
| HMHB1 | CACNB2 | 0.74304 | 4 | 0 | 3 |
| HMHB1 | ADCY5 | 0.741001 | 4 | 0 | 4 |
| HMHB1 | BHMT2 | 0.737506 | 3 | 0 | 3 |
| HMHB1 | PYGM | 0.737315 | 4 | 0 | 3 |
| HMHB1 | SSBP2 | 0.73582 | 3 | 0 | 3 |
| HMHB1 | CYP21A2 | 0.727823 | 3 | 0 | 3 |
| HMHB1 | SORCS1 | 0.718701 | 3 | 0 | 3 |
| HMHB1 | CFL2 | 0.717853 | 3 | 0 | 3 |
For details and further investigation, click here
