| Full name: thioredoxin related transmembrane protein 4 | Alias Symbol: DJ971N18.2|KIAA1162|PDIA14 | ||
| Type: protein-coding gene | Cytoband: 20p12.3 | ||
| Entrez ID: 56255 | HGNC ID: HGNC:25237 | Ensembl Gene: ENSG00000125827 | OMIM ID: 616766 |
| Drug and gene relationship at DGIdb | |||
Expression of TMX4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMX4 | 56255 | 201581_at | -1.4351 | 0.1557 | |
| GSE20347 | TMX4 | 56255 | 201580_s_at | -0.7849 | 0.0006 | |
| GSE23400 | TMX4 | 56255 | 201580_s_at | -0.2061 | 0.0032 | |
| GSE26886 | TMX4 | 56255 | 201581_at | -0.2521 | 0.6398 | |
| GSE29001 | TMX4 | 56255 | 201581_at | -0.5895 | 0.3547 | |
| GSE38129 | TMX4 | 56255 | 201581_at | -1.1513 | 0.0008 | |
| GSE45670 | TMX4 | 56255 | 201581_at | -1.3383 | 0.0000 | |
| GSE53622 | TMX4 | 56255 | 125151 | -0.4812 | 0.0001 | |
| GSE53624 | TMX4 | 56255 | 125151 | -0.4116 | 0.0000 | |
| GSE63941 | TMX4 | 56255 | 201580_s_at | -1.8761 | 0.0136 | |
| GSE77861 | TMX4 | 56255 | 201580_s_at | -0.4571 | 0.1473 | |
| GSE97050 | TMX4 | 56255 | A_24_P250535 | -0.0796 | 0.8836 | |
| SRP007169 | TMX4 | 56255 | RNAseq | -0.8645 | 0.0541 | |
| SRP008496 | TMX4 | 56255 | RNAseq | -0.1464 | 0.6239 | |
| SRP064894 | TMX4 | 56255 | RNAseq | -0.2056 | 0.2153 | |
| SRP133303 | TMX4 | 56255 | RNAseq | -0.3062 | 0.1036 | |
| SRP159526 | TMX4 | 56255 | RNAseq | 0.6107 | 0.1222 | |
| SRP193095 | TMX4 | 56255 | RNAseq | -0.3715 | 0.0077 | |
| SRP219564 | TMX4 | 56255 | RNAseq | -0.2545 | 0.6437 | |
| TCGA | TMX4 | 56255 | RNAseq | -0.2992 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMX4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMX4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMX4 | 56255 | 10 | 2 | 18 | |
| GSE20123 | TMX4 | 56255 | 10 | 2 | 18 | |
| GSE43470 | TMX4 | 56255 | 12 | 1 | 30 | |
| GSE46452 | TMX4 | 56255 | 26 | 1 | 32 | |
| GSE47630 | TMX4 | 56255 | 18 | 4 | 18 | |
| GSE54993 | TMX4 | 56255 | 1 | 14 | 55 | |
| GSE54994 | TMX4 | 56255 | 25 | 2 | 26 | |
| GSE60625 | TMX4 | 56255 | 0 | 0 | 11 | |
| GSE74703 | TMX4 | 56255 | 9 | 1 | 26 | |
| GSE74704 | TMX4 | 56255 | 5 | 1 | 14 | |
| TCGA | TMX4 | 56255 | 40 | 11 | 45 |
Total number of gains: 156; Total number of losses: 39; Total Number of normals: 293.
Somatic mutations of TMX4:
Generating mutation plots.
Highly correlated genes for TMX4:
Showing top 20/1309 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMX4 | FIBIN | 0.777785 | 5 | 0 | 5 |
| TMX4 | UBE2R2 | 0.767723 | 3 | 0 | 3 |
| TMX4 | ZNF583 | 0.765644 | 3 | 0 | 3 |
| TMX4 | GPRASP2 | 0.757955 | 3 | 0 | 3 |
| TMX4 | CYP4V2 | 0.753954 | 4 | 0 | 4 |
| TMX4 | SNX25 | 0.749381 | 4 | 0 | 4 |
| TMX4 | AFF3 | 0.743764 | 4 | 0 | 4 |
| TMX4 | DLD | 0.742747 | 3 | 0 | 3 |
| TMX4 | C11orf96 | 0.732187 | 4 | 0 | 3 |
| TMX4 | PPID | 0.728191 | 3 | 0 | 3 |
| TMX4 | ZNF25 | 0.7133 | 7 | 0 | 7 |
| TMX4 | ENG | 0.708224 | 3 | 0 | 3 |
| TMX4 | ARHGAP31 | 0.707644 | 6 | 0 | 6 |
| TMX4 | LRRN4CL | 0.706599 | 6 | 0 | 6 |
| TMX4 | MAP3K8 | 0.704625 | 3 | 0 | 3 |
| TMX4 | GALNT11 | 0.702948 | 4 | 0 | 4 |
| TMX4 | ECSCR | 0.702006 | 4 | 0 | 4 |
| TMX4 | KCNJ2 | 0.698891 | 3 | 0 | 3 |
| TMX4 | CNRIP1 | 0.695641 | 6 | 0 | 5 |
| TMX4 | C1QTNF7 | 0.695379 | 5 | 0 | 5 |
For details and further investigation, click here
