| Full name: TNF superfamily member 13 | Alias Symbol: APRIL|CD256 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 8741 | HGNC ID: HGNC:11928 | Ensembl Gene: ENSG00000161955 | OMIM ID: 604472 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFSF13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFSF13 | 8741 | 210314_x_at | 0.1533 | 0.7324 | |
| GSE20347 | TNFSF13 | 8741 | 210314_x_at | 0.2601 | 0.1146 | |
| GSE23400 | TNFSF13 | 8741 | 210314_x_at | 0.0629 | 0.2706 | |
| GSE26886 | TNFSF13 | 8741 | 210314_x_at | 0.7555 | 0.0099 | |
| GSE29001 | TNFSF13 | 8741 | 210314_x_at | 0.4387 | 0.0947 | |
| GSE38129 | TNFSF13 | 8741 | 210314_x_at | 0.2690 | 0.1251 | |
| GSE45670 | TNFSF13 | 8741 | 210314_x_at | -0.2078 | 0.2306 | |
| GSE63941 | TNFSF13 | 8741 | 210314_x_at | 0.8413 | 0.4912 | |
| GSE77861 | TNFSF13 | 8741 | 210314_x_at | 0.1383 | 0.5728 | |
| GSE97050 | TNFSF13 | 8741 | A_23_P152620 | 0.3272 | 0.6563 | |
| SRP007169 | TNFSF13 | 8741 | RNAseq | 1.0242 | 0.0457 | |
| SRP008496 | TNFSF13 | 8741 | RNAseq | 1.2210 | 0.0017 | |
| SRP064894 | TNFSF13 | 8741 | RNAseq | 0.5516 | 0.1290 | |
| SRP133303 | TNFSF13 | 8741 | RNAseq | 0.4890 | 0.0025 | |
| SRP159526 | TNFSF13 | 8741 | RNAseq | 0.4171 | 0.2673 | |
| SRP193095 | TNFSF13 | 8741 | RNAseq | -0.0195 | 0.9501 | |
| SRP219564 | TNFSF13 | 8741 | RNAseq | 1.1943 | 0.0248 | |
| TCGA | TNFSF13 | 8741 | RNAseq | -0.5355 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TNFSF13 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TNFSF13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFSF13 | 8741 | 4 | 2 | 24 | |
| GSE20123 | TNFSF13 | 8741 | 4 | 3 | 23 | |
| GSE43470 | TNFSF13 | 8741 | 1 | 4 | 38 | |
| GSE46452 | TNFSF13 | 8741 | 34 | 1 | 24 | |
| GSE47630 | TNFSF13 | 8741 | 7 | 1 | 32 | |
| GSE54993 | TNFSF13 | 8741 | 4 | 3 | 63 | |
| GSE54994 | TNFSF13 | 8741 | 5 | 8 | 40 | |
| GSE60625 | TNFSF13 | 8741 | 4 | 0 | 7 | |
| GSE74703 | TNFSF13 | 8741 | 1 | 2 | 33 | |
| GSE74704 | TNFSF13 | 8741 | 2 | 1 | 17 | |
| TCGA | TNFSF13 | 8741 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of TNFSF13:
Generating mutation plots.
Highly correlated genes for TNFSF13:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFSF13 | WDR81 | 0.788376 | 3 | 0 | 3 |
| TNFSF13 | INHBB | 0.779214 | 3 | 0 | 3 |
| TNFSF13 | PLCB2 | 0.75269 | 3 | 0 | 3 |
| TNFSF13 | TRIM47 | 0.740875 | 4 | 0 | 4 |
| TNFSF13 | RRNAD1 | 0.735663 | 3 | 0 | 3 |
| TNFSF13 | NPRL3 | 0.733923 | 4 | 0 | 4 |
| TNFSF13 | SORBS3 | 0.733721 | 3 | 0 | 3 |
| TNFSF13 | CHST11 | 0.732804 | 3 | 0 | 3 |
| TNFSF13 | TMEM150A | 0.724697 | 3 | 0 | 3 |
| TNFSF13 | SSBP4 | 0.721891 | 4 | 0 | 4 |
| TNFSF13 | AOAH | 0.720248 | 3 | 0 | 3 |
| TNFSF13 | INO80E | 0.717402 | 3 | 0 | 3 |
| TNFSF13 | PDE4B | 0.715971 | 3 | 0 | 3 |
| TNFSF13 | CMTM7 | 0.715249 | 3 | 0 | 3 |
| TNFSF13 | TTLL1 | 0.713721 | 3 | 0 | 3 |
| TNFSF13 | CNTROB | 0.712904 | 3 | 0 | 3 |
| TNFSF13 | NRSN2 | 0.710887 | 3 | 0 | 3 |
| TNFSF13 | SIDT2 | 0.707071 | 4 | 0 | 3 |
| TNFSF13 | SMARCD2 | 0.703026 | 4 | 0 | 3 |
| TNFSF13 | PIK3AP1 | 0.701814 | 3 | 0 | 3 |
For details and further investigation, click here
