INHBB

 

Full name: inhibin subunit beta B Alias Symbol: 
Type: protein-coding gene Cytoband: 2q14.2
Entrez ID: 3625 HGNC ID: HGNC:6067 Ensembl Gene: ENSG00000163083 OMIM ID: 147390
Drug and gene relationship at DGIdb

 

INHBB involved pathways:

KEGG pathway Description View
hsa04350TGF-beta signaling pathway
hsa04550Signaling pathways regulating pluripotency of stem cells

 

Expression of INHBB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 INHBB 3625 205258_at 0.3001 0.7249
GSE20347 INHBB 3625 205258_at 0.9176 0.0010
GSE23400 INHBB 3625 205258_at 0.3834 0.0002
GSE26886 INHBB 3625 205258_at 1.5219 0.0001
GSE29001 INHBB 3625 205258_at 0.8074 0.0795
GSE38129 INHBB 3625 205258_at 0.9534 0.0069
GSE45670 INHBB 3625 205258_at 0.6114 0.0757
GSE53622 INHBB 3625 99451 0.7431 0.0015
GSE53624 INHBB 3625 99451 1.0212 0.0000
GSE63941 INHBB 3625 205258_at 1.7946 0.1311
GSE77861 INHBB 3625 205258_at 1.3458 0.0013
GSE97050 INHBB 3625 A_23_P153964 0.7244 0.1566
SRP064894 INHBB 3625 RNAseq 1.5512 0.0001
SRP133303 INHBB 3625 RNAseq 1.5382 0.0068
SRP159526 INHBB 3625 RNAseq 2.2808 0.0000
SRP219564 INHBB 3625 RNAseq 1.3795 0.0249
TCGA INHBB 3625 RNAseq 0.0995 0.5932

Upregulated datasets: 7; Downregulated datasets: 0.  

 

Survival by INHBB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of INHBB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 INHBB 3625 6 2 22
GSE20123 INHBB 3625 6 2 22
GSE43470 INHBB 3625 3 1 39
GSE46452 INHBB 3625 2 3 54
GSE47630 INHBB 3625 6 0 34
GSE54993 INHBB 3625 0 6 64
GSE54994 INHBB 3625 12 0 41
GSE60625 INHBB 3625 0 3 8
GSE74703 INHBB 3625 3 1 32
GSE74704 INHBB 3625 3 1 16
TCGA INHBB 3625 32 6 58

Total number of gains: 73; Total number of losses: 25; Total Number of normals: 390.  

 

Somatic mutations of INHBB:

 

Generating mutation plots.

 

Highly correlated genes for INHBB:

 

Showing top 20/940 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
INHBBTNFSF130.779214303
INHBBOCIAD20.761196404
INHBBRAVER10.750634303
INHBBZCCHC70.749102303
INHBBLTF0.743099303
INHBBRPL190.729073303
INHBBPCYT1A0.725649404
INHBBTOP1MT0.721495404
INHBBYWHAG0.718197303
INHBBZNF6220.71341404
INHBBNACC10.711879303
INHBBNUP2050.711636303
INHBBC1QC0.706797303
INHBBMIEN10.705478303
INHBBMTRR0.700303303
INHBBPSMD140.697147504
INHBBVMA210.693848403
INHBBLANCL20.688707303
INHBBACBD60.685434303
INHBBAGK0.684052303

For details and further investigation, click here