CHST11

 

Full name: carbohydrate sulfotransferase 11 Alias Symbol: C4ST1|C4St-1|C4ST|HSA269537
Type: protein-coding gene Cytoband: 12q23.3
Entrez ID: 50515 HGNC ID: HGNC:17422 Ensembl Gene: ENSG00000171310 OMIM ID: 610128
Drug and gene relationship at DGIdb

 

Expression of CHST11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CHST11 50515 226372_at 1.2105 0.0895
GSE20347 CHST11 50515 219634_at 0.7676 0.0043
GSE23400 CHST11 50515 219634_at 0.3976 0.0000
GSE26886 CHST11 50515 226372_at 1.2847 0.0037
GSE29001 CHST11 50515 219634_at 0.4488 0.0286
GSE38129 CHST11 50515 219634_at 1.0720 0.0000
GSE45670 CHST11 50515 226372_at 1.2939 0.0014
GSE53622 CHST11 50515 2765 1.5235 0.0000
GSE53624 CHST11 50515 30408 1.4271 0.0000
GSE63941 CHST11 50515 226372_at 1.1486 0.3057
GSE77861 CHST11 50515 226372_at 0.2728 0.4797
GSE97050 CHST11 50515 A_23_P139919 1.2450 0.0948
SRP007169 CHST11 50515 RNAseq 2.8456 0.0001
SRP008496 CHST11 50515 RNAseq 2.3483 0.0000
SRP064894 CHST11 50515 RNAseq 2.1076 0.0000
SRP133303 CHST11 50515 RNAseq 1.8776 0.0000
SRP193095 CHST11 50515 RNAseq 1.8859 0.0000
TCGA CHST11 50515 RNAseq 0.4849 0.0002

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by CHST11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CHST11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CHST11 50515 4 2 24
GSE20123 CHST11 50515 4 3 23
GSE43470 CHST11 50515 2 0 41
GSE46452 CHST11 50515 9 1 49
GSE47630 CHST11 50515 9 1 30
GSE54993 CHST11 50515 0 5 65
GSE54994 CHST11 50515 4 2 47
GSE60625 CHST11 50515 0 0 11
GSE74703 CHST11 50515 2 0 34
GSE74704 CHST11 50515 1 2 17
TCGA CHST11 50515 19 11 66

Total number of gains: 54; Total number of losses: 27; Total Number of normals: 407.  

 

Somatic mutations of CHST11:

 

Generating mutation plots.

 

Highly correlated genes for CHST11:

 

Showing top 20/1709 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CHST11ALPK20.804387303
CHST11TMC80.759357303
CHST11ST8SIA40.75577303
CHST11C17orf670.74909303
CHST11IKBIP0.744035606
CHST11TTYH30.743408707
CHST11MAD2L20.738864504
CHST11FCGR3A0.738168303
CHST11FMNL20.737862707
CHST11TNFSF130.732804303
CHST11ZBTB90.731801303
CHST11RAB340.729773303
CHST11PDE7A0.729514706
CHST11AGTRAP0.727356505
CHST11SPON20.727041303
CHST11PREX10.726633303
CHST11SH3PXD2B0.725767706
CHST11ZNF6280.725554303
CHST11LRRC8C0.722156303
CHST11WDR540.721969706

For details and further investigation, click here