SAC3D1

 

Full name: SAC3 domain containing 1 Alias Symbol: HSU79266|SHD1
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 29901 HGNC ID: HGNC:30179 Ensembl Gene: ENSG00000168061 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SAC3D1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SAC3D1 29901 205449_at 1.2576 0.0240
GSE20347 SAC3D1 29901 205449_at 0.8978 0.0000
GSE23400 SAC3D1 29901 205449_at 1.0607 0.0000
GSE26886 SAC3D1 29901 205449_at 1.5312 0.0000
GSE29001 SAC3D1 29901 205449_at 1.1294 0.0028
GSE38129 SAC3D1 29901 205449_at 1.0247 0.0000
GSE45670 SAC3D1 29901 205449_at 0.8986 0.0000
GSE53622 SAC3D1 29901 89979 0.6608 0.0000
GSE53624 SAC3D1 29901 89979 1.1665 0.0000
GSE63941 SAC3D1 29901 205449_at 0.4469 0.3686
GSE77861 SAC3D1 29901 205449_at 1.0647 0.0020
GSE97050 SAC3D1 29901 A_23_P348298 0.4012 0.2653
SRP007169 SAC3D1 29901 RNAseq 0.3256 0.4842
SRP008496 SAC3D1 29901 RNAseq 1.1959 0.0010
SRP064894 SAC3D1 29901 RNAseq 1.7686 0.0001
SRP133303 SAC3D1 29901 RNAseq 0.6221 0.0055
SRP159526 SAC3D1 29901 RNAseq 1.1234 0.0001
SRP193095 SAC3D1 29901 RNAseq 0.5395 0.0002
SRP219564 SAC3D1 29901 RNAseq 0.8412 0.0761
TCGA SAC3D1 29901 RNAseq 0.4900 0.0000

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by SAC3D1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SAC3D1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SAC3D1 29901 7 6 17
GSE20123 SAC3D1 29901 7 6 17
GSE43470 SAC3D1 29901 2 3 38
GSE46452 SAC3D1 29901 10 4 45
GSE47630 SAC3D1 29901 5 6 29
GSE54993 SAC3D1 29901 3 0 67
GSE54994 SAC3D1 29901 6 5 42
GSE60625 SAC3D1 29901 0 3 8
GSE74703 SAC3D1 29901 2 1 33
GSE74704 SAC3D1 29901 5 4 11
TCGA SAC3D1 29901 23 7 66

Total number of gains: 70; Total number of losses: 45; Total Number of normals: 373.  

 

Somatic mutations of SAC3D1:

 

Generating mutation plots.

 

Highly correlated genes for SAC3D1:

 

Showing top 20/1815 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SAC3D1IPO90.768113808
SAC3D1FEN10.76366411011
SAC3D1EIF3B0.75978410010
SAC3D1CMSS10.757633606
SAC3D1MCM80.7504606
SAC3D1CDCA50.745666908
SAC3D1CKAP50.74465810010
SAC3D1SSRP10.74332211010
SAC3D1TOR3A0.74331610010
SAC3D1RUVBL10.739783909
SAC3D1NUF20.739016606
SAC3D1TMC80.737881303
SAC3D1MRGBP0.73616110010
SAC3D1CKS1B0.73596511010
SAC3D1DNMT10.73465211010
SAC3D1MTBP0.732709404
SAC3D1UBE2T0.730937706
SAC3D1WDR740.7306541009
SAC3D1KNSTRN0.72995606
SAC3D1AGRN0.72907910010

For details and further investigation, click here